Notes

Desorption electrospray ionization (DESI) supply combining range of motion size spectrometry for image resolution fluoropezil (DC20) submission inside rat mind.
Clinical relevance- The automatic monitoring of food intake using wearable devices can play a pivotal role in the treatment and prevention of eating disorders, obesity, malnutrition and other related issues. It can aid in understanding the pattern of nutritional intake and make personalized adjustments to lead a healthy life.Chagas disease is a widely spreaded illness caused by the parasite Trypanosoma cruzi (T. cruzi). Most cases go unnoticed until the accumulated myocardial damage affect the patient. The endomyocardium biopsy is a tool to evaluate sustained myocardial damage, but analyzing histopathological images takes a lot of time and its prone to human error, given its subjective nature. The following work presents a deep learning method to detect T. cruzi amastigotes on histopathological images taken from a endomyocardium biopsy during an experimental murine model. A U-Net convolutional neural network architecture was implemented and trained from the ground up. Oseltamivir Neuraminidase inhibitor An accuracy of 99.19% and Jaccard index of 49.43% were achieved. The obtained results suggest that the proposed approach can be useful for amastigotes detection in histopathological images.Clinical relevance- The proposed method can be incorporated as automatic detection tool of amastigotes nests, it can be useful for the Chagas disease analysis and diagnosis.Machine learning algorithms are progressively assuming important roles as computational tools to support clinical diagnosis, namely in the classification of pigmented skin lesions using RGB images. Most current classification methods rely on common 2D image features derived from shape, colour or texture, which does not always guarantee the best results. This work presents a contribution to this field, by exploiting the lesions' border line characteristics using a new dimension - depth, which has not been thoroughly investigated so far. A selected group of features is extracted from the depth information of 3D images, which are then used for classification using a quadratic Support Vector Machine. Despite class imbalance often present in medical image datasets, the proposed algorithm achieves a top geometric mean of 94.87%, comprising 100.00% sensitivity and 90.00% specificity, using only depth information for the detection of Melanomas. Such results show that potential gains can be achieved by extracting information from this often overlooked dimension, which provides more balanced results in terms of sensitivity and specificity than other settings.Automatic analysis of fetal heart and related components in fetal echocardiography can help cardiologists to reach a diagnosis for Congenital Heart Disease (CHD). Previous studies mainly focused on cardiac chamber segmentation, while few researches deal with the cardiac component detection. In this paper, we tackle the task of simultaneous detection of the fetal heart and descending aorta in four-chamber view of fetal echocardiography, which is useful to analyze some kinds of CHD, such as left/right atrial isomerism, dextroversion of heart, etc. Several CNN-based object detection methods with different backbones are thoroughly evaluated, and finally, the Hybrid Task Cascade method with HRNet is selected as the detection method. Experiments on a fetal echocardiography dataset show that the method can achieve superior performance according to common-used evaluation metrics.Clinical relevance-This can be used to help the cardiologists to estimate the position of the fetal heart and the descending aorta, which is also useful to estimate the direction of the cardiac axis and apex and analyze some kinds of CHD, such as left/right atrial isomerism, dextroversion of heart, etc.In this work we try to address if there is a better way to classify two distributions, rather than using histograms; and answer if we can make a deep learning network learn and classify distributions automatically. These improvements can have wide ranging applications in computer vision and medical image processing. More specifically, we propose a new vessel segmentation method based on pixel distribution learning under multiple scales. In particular, a spatial distribution descriptor named Random Permutation of Spatial Pixels (RPoSP) is derived from vessel images and used as the input to a convolutional neural network for distribution learning. Based on our preliminary experiments we currently believe that a wide network, rather than a deep one, is better for distribution learning. There is only one convolutional layer, one rectified linear layer and one fully connected layer followed by a softmax loss in our network. Furthermore, in order to improve the accuracy of the proposed approach, the RPoSP features are captured at multiple scales and combined together to form the input of the network. Evaluations using standard benchmark datasets demonstrate that the proposed approach achieves promising results compared to the state-of-the-art.Convolutional neural networks are increasingly used in the medical field for the automatic segmentation of several anatomical regions on diagnostic and non-diagnostic images. Such automatic algorithms allow to speed up time-consuming processes and to avoid the presence of expert personnel, reducing time and costs. The present work proposes the use of a convolutional neural network, the U-net architecture, for the segmentation of ear elements. The auricular elements segmentation process is a crucial step of a wider procedure, already automated by the authors, that has as final goal the realization of surgical guides designed to assist surgeons in the reconstruction of the external ear. The segmentation, performed on depth map images of 3D ear models, aims to define of the contour of the helix, antihelix, tragus-antitragus and concha. A dataset of 131 ear depth map was created;70% of the data are used as the training set, 15% composes the validation set, and the remaining 15% is used as testing set. The network showed excellent performance, achieving 97% accuracy on the validation test.Ultrasound (US) imaging is becoming the routine modality for the diagnosis and prognosis of lung pathologies. Lung US imaging relies on artifacts from acoustic impedance (Z) mismatches to distinguish and interpret the normal and pathological lung conditions. The air-pleura interface of the normal lung displays specularity due to the huge Z mismatches. However, in the presence of pathologies, the interface alters exhibiting a diffuse behavior due to increased density and reduced spatial distribution of air in the sub-pleural space. The specular or the diffuse behavior influences the reflected acoustic intensity distribution. This study aims to understand the reflection pattern in a normal and pathological lung through a novel approach of determining pixel-level acoustic intensity vector field (IVF) at high frame rates. Detailed lung modeling procedures using k-Wave US toolbox under normal, edematous, and consolidated conditions are illustrated. The analysis of the IVF maps on the three lung models clearly shows the drifting of the air-pleura interface from specular to diffuse with the severity of the pathology.Clinical Relevance- The presented acoustic simulation lung models are an aid to teaching and research by providing a quick visual and intuitive understanding of lung ultrasound physics. The proposed intensity vector field maps are supplementary information to aid diagnostics and characterization of any tissue composed of specular and diffuse components.As an inverse problem, parallel magnetic resonance imaging (pMRI) reconstruction accelerates imaging speed by interpolating missing k-space data from a group of phased-array coils. Deep learning methods have been used for improving pMRI reconstruction quality in recent years. However, deep learning approaches need a large amount of training data that are acquired from different hardware configurations and anatomical areas. Data distributions may be different between training data and testing data, and a long-time training is needed. In this work, we proposed a broad learning system based parallel MRI reconstruction that exploits approximation capability of one-layer neural network through broadening network structure with expanded nodes. Experimental results show that the proposed method is able to suppress noise in compared to the conventional pMRI reconstruction.Recent studies have shown that Dental Panoramic Radiograph (DPR) images have great potential for prescreening of osteoporosis given the high degree of correlation between the bone density and trabecular bone structure. Most of the research works in these area had used pretrained models for feature extraction and classification with good success. However, when the size of the data set is limited it becomes difficult to use these pretrained networks and gain high confidence scores. In this paper, we evaluated the diagnostic performance of deep convolutional neural networks (DCNN)based computer-assisted diagnosis (CAD) system in the detection of osteoporosis on panoramic radiographs, through a comparison with diagnoses made by oral and maxillofacial radiologists. With the available labelled dataset of 70 images, results were reproduced for the preliminary study model. Furthermore, the model performance was enhanced using different computer vision techniques. Specifically, the age meta data available for each patient was leveraged to obtain more accurate predictions. Lastly, we tried to leverage these images, ages and osteoporotic labels to create a neural network based regression model and predict the Bone Mineral Density (BMD) value for each patient. Experimental results showed that the proposed CAD system was in high accord with experienced oral and maxillofacial radiologists in detecting osteoporosis and achieved 87.86% accuracy.Clinical relevance- This paper presents a method to detect osteoporosis using DPR images and age data with multi-column DCNN and then leverage this data to predict Bone Mineral Density for each patient.The magnetic nanoparticles have been widely explored as an important kind of biomaterial for the treatment and diagnosis of cancer. Imaging of magnetic nanoparticles can greatly facilitate treatment and diagnosis in both preclinical and clinical applications. The magnetoacoustic tomography is a non-invasive imaging modality for the distribution of the magnetic nanoparticles. However, the traditional magnetoacoustic imaging system requires higher power and the large instantaneous current that suffers cost and safety issues. In this paper, we propose a low-power magnetoacoustic tomography system, whose power amplifier only has 30 W peak power. The system used a pulse train of excitation to gain energy accumulation by resonance. The reconstructed algorithm, i.e. universal back-projection, was applied for imaging. To prove the feasibility and potential of the proposed system, we performed the imaging experiments with the gelatin phantom containing the magnetic nanoparticles.Diabetic Retinopathy is a major cause of vision loss caused by retina lesions, including hard and soft exudates, microaneurysms, and hemorrhages. The development of a computational tool capable of detecting these lesions can assist in the early diagnosis of the most severe forms of the lesions and assist in the screening process and definition of the best treatment form. This paper proposes a computational model based on pre-trained convolutional neural networks capable of detecting fundus lesions to promote medical diagnosis support. The model was trained, adjusted, and evaluated using the DDR Diabetic Retinopathy dataset and implemented based on a YOLOv4 architecture and Darknet framework, reaching an mAP of 11.13% and a mIoU of 13.98%. The experimental results show that the proposed model presented results superior to those obtained in related works found in the literature.
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