Notes

What is the Function regarding Force in Fixing Scaphocephaly By means of Spring-Mediated Cranial Container Expansion for Sagittal Craniosynostosis?
Recent reports on COVID-19 suggest, the susceptibility to COVID-19 and its progression have a genetic predisposition. Majorly associated genetic variants are found in human leukocyte antigen (HLA), angiotensin convertase enzyme (ACE; rs1799752 ACE2; rs73635825), transmembrane protease serine 2 (TMPRSS-2; rs12329760) genes. Identifying highly prone population having these variants is imperative for determining COVID-19 therapeutic strategy. Ayurveda (Indian traditional system of medicine) concept of Prakriti holds potential to predict genomic and phenotypic variations. Reported work on Prakriti correlates HLA-DR alleles with three broad phenotypes (Tridosha) described in Ayurveda (AyuGenomics). This is suggestive of differences in immune responses in individuals with specific constitutions. Therefore, the reported studies provide clues for clinically relevant hypotheses to be tested in systematic studies. The proposed approach of Ayurveda based phenotype screening may offer a way ahead to design customized strategies for management of COVID-19 based on differences in Prakriti, immune response and drug response. However, this needs clinical evaluation of the relation between Prakriti and genetic or phenotypic variants in COVID-19 prone and resistant populations.The COVID 19 pandemic has caused mayhem globally since the beginning of 2020. Due to the immune dysfunction inherent to cirrhosis and the poor general condition, patients with chronic liver disease (CLD) are at higher risk of mortality and morbidity due to COVID-19. Recently a number of vaccines against SARS-Cov-2 have been granted approval for emergency use around the globe. Although the phase 2/3 trials of these vaccines show them to be safe and effective in the general population, data in patients with CLD is scarce. The number of patients with CLD enrolled into these trials is small; no liver related adverse effects have been reported yet. Various liver societies have come up with guidelines on vaccination in this population and recommend vaccination on a priority basis. Trials to assess the safety and efficacy of the COVID vaccines are under way and are likely to provide valuable insight into this matter.
The standard treatment of Aneurysmal bone cyst is curettage and grafting and is associated with high morbidity. Hence minimal invasive alternative treatment methods such as sclerotherapy are gaining much popularity. Though sclerotherapy has been attributed to reasonable cure rates, undetermined tissue diagnosis often impedes with initiation of treatment. This study examines if sclerotherapy with polidocanol based on clinic-radiological picture is comparable with the standard intralesional curettage and bone grafting. Attempting biopsy and treatment simultaneously based on the clinico-radiological presentation makes this study unique.

We divided 48 patients into two treatment groups. Group 1 treated with percutaneous sclerotherapy using polidocanol and group 2 those treated with extended curettage and bone grafting. We assessed time to healing and recurrence, pain relief, and radiological outcome using modified Neer's criteria for the radiological healing of the bone cysts. 31 patients from Group 1 and 17 a highly effective, cost efficient and safe treatment option with good cosmesis and reduced morbidity. In this study, we found comparable outcomes for both treatment methods however this will require confirmation in larger studies.
This study assessed revision characteristics following distal femur tumor endoprosthetic replacement.

Fifty-seven procedures were performed between 2005 and 2019. The cumulative incidence of implant revision was calculated with death as a competing risk.

The all-cause revision rate was 21.1% (n=12) at a mean 65.3±47.3 months. Alizarin Red S purchase Competing risk analysis revealed a cumulative revision incidence of 12.0% (95% CI, 3.6-25.9%) at five years and 36.5% (95% CI, 12.8-61.0%) at ten years.

We provide an accurate assessment of revision risk which is slightly lower than historical controls, with identification of failure modes to reliably inform patient expectations.

III. Retrospective Study.
III. Retrospective Study.
Coronavirus belongs to family of Coronaviridae, which primarily infect the upper respiratory and gastro intestinal tract of birds & mammals. It is an enveloped virus with positive-sense single-stranded RNA. Patients with COVID-19 are usually present with symptoms of fever, dry cough, myalgia, dysgeusia, nausea, diarrhoea, hyposmia and later it progresses into pneumonia. Dentists are at potential risk because they are in consistent exposure of blood and saliva, so they should have knowledge of COVID-19 infection, transmission & prevention for proper infection control practices.

The aim of the study is to assess the knowledge and perception of DHPs toward COVID-19.

A cross-sectional study was undertaken among practicing dental professionals in Lucknow city (U.P) India. A total of 302 Dental Health Practitioners (DHPs) participated in the study. Knowledge was assessed using self-administered, structured questionnaire. The questions were administered online through Google Forms by sending link to thwhile working in their respective field due to COVID-19 impact. DHPs are advised to follow the guidelines for clinical recommendations given by health authorities like WHO, CDC, ADA and IDA."Clean Hands Save Lives," we have heard it numerous times. But are our hands really clean? We realized that the most neglected parts of our hands are the most medial part of the little finger and palm and the most lateral part of the index finger and palm. Putting an emphasis on it, we put forward two additional steps in the routine handwashing technique increasing to 9 steps instead of the previous 7. How to cite this article Bajaj A, Chaurasiya N, Tripathi M. Are Our Hands Still Clean? Indian J Crit Care Med 2021;25(5)601-602.How to cite this article Naaz S, Kumar A, Sahay N, Kumar R, Ozair E, Valiaparambath A. Defecation and Micturition may Cause Syncope in COVID-19 Patients on High Oxygen Requirement. Indian J Crit Care Med 2021;25(5)599-600.
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