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This study aims to investigate risk indicators of in-hospital mortality and severity of coronavirus disease-2019 (COVID-19) in patients with diabetes mellitus (DM).
In this retrospective study, we studied patients with COVID-19 referred to Sina Hospital, Tehran, Iran, from February 20 to May 14, 2020. Patients with either a positive real-time reverse-transcriptase polymerase-chain-reaction test of swab specimens or high clinical suspicion according to the World Health Organization interim guidance were included. We accurately divided all patients into two groups based on diabetes affection and followed-up patients with DM based on incurring death, severe COVID-19, and in-hospital complications.
We enrolled 574 patients with COVID-19 in the final analysis, of whom 176 (30.7%) patients had DM. In this study, 104 (18.1%) patients deceased, and 380 (66.2%) patients incurred severe COVID-19. We found that COVID-19 patients with DM had a significantly higher mortality rate (
value<0.001), severe disease (
value<0.001), and in-hospital complications (all
values<0.05). Besides that, in patients with DM, admission temperature (odds ratio (OR) 1.69, P value 0.024), oxygen saturation (OR 0.92, P value 0.004), and urea (OR 1.01, P value 0.048) were independent risk indicators of in-hospital mortality. In addition, subgroup analysis of diabetic patients based on admission glucose level showed significant differences between these groups regarding acute cardiac injury (
value 0.044) and acute liver injury (P value 0.002).
Patients with DM admitted with lower oxygen saturation, elevated temperature, and higher urea are more susceptible to progress to more severe COVID-19 and poor prognosis. This indicates a necessity for more precise care during hospitalization for these patients.
The online version contains supplementary material available at 10.1007/s40200-020-00701-2.
The online version contains supplementary material available at 10.1007/s40200-020-00701-2.Otorhinolaryngologists, particularly dealing with airway cases, are subjected to highest risk of COVID 19 aerosolisation, self infection and transmission. Moreover, airway cases, which mostly present as emergency, cannot be deferred. Being a tertiary airway centre and having received a number of airway cases, most of them requiring prompt surgical intervention, our airway surgery and anaesthesiology team had to work in conjunction to adapt and readapt the practice over the past few months, striving to achieve effective airway surgery protocols, to minimize exposure and prevent transmission of COVID 19. To enlist the encountered airway cases during COVID 19 pandemic and to highlight the important inclusions and adaptations in executing the airway surgeries. A retrospective observational study of 7 months duration was carried out. This is a single institutional study, where the sample included the primary as well the referred airway cases. Apart from Tracheotomy, Foreign body bronchus removal, Dilatation of Laryngotracheal Stenosis (LTS) and excision of Recurrent Respiratory Papillomatosis (RRP), we also have had the experience to deal with congenital Laryngo-tracheo-oesophageal Cleft (LTOC) Type III b, Thyroid surgery to relieve tracheal compression and Bilateral Choanal Atresia repair during the last 7 months. Routine 2 weeks follow up of the patients have been favourable, as there has not been any report or clinical features of transmission of COVID 19. selleck kinase inhibitor As the airway surgeries could be executed with the incorporation of certain change in practice and as the follow up revealed no evidence of transmission, we attempt to contribute to airway best practice guideline for maintaining the safety of patients and health professionals.The research work in this paper attempts to describe the outbreak of Coronavirus Disease 2019 (COVID-19) with the help of a mathematical model using both the Ordinary Differential Equation (ODE) and Fractional Differential Equation. The spread of the disease has been on the increase across the globe for some time with no end in sight. The research used the data of COVID-19 cases in Nigeria for the numerical simulation which has been fitted to the model. We brought in the consideration of both asymptomatic and symptomatic infected individuals with the fact that an exposed individual is either sent to quarantine first or move to one of the infected classes with the possibility that susceptible individual can also move to quarantined class directly. It was found that the proposed model has two equilibrium points; the disease-free equilibrium point ( DFE ) and the endemic equilibrium point ( E 1 ) . Stability analysis of the equilibrium points shows ( E 0 ) is locally asymptotically stable whenever the basic reproduction number, R 0 1 . Sensitivity analysis of the parameters in the R 0 was conducted and the profile of each state variable was also depicted using the fitted values of the parameters showing the spread of the disease. The most sensitive parameters in the R 0 are the contact rate between susceptible individuals and the rate of transfer of individuals from exposed class to symptomatically infected class. Moreover, the basic reproduction number for the data is calculated as R 0 ≈ 1.7031 . Existence and uniqueness of solution established via the technique of fixed point theorem. Also, using the least square curve fitting method together with the fminsearch function in the MATLAB optimization toolbox, we obtain the best values for some of the unknown biological parameters involved in the proposed model. Furthermore, we solved the fractional model numerically using the Atangana-Toufik numerical scheme and presenting different forms of graphical results that can be useful in minimizing the infection.
COVID-19 incidence became a pandemic immediately after its origin and spread. Apart from death because of coronavirus infection, the pandemic brought unbearable psychological pressure to all. We assessed the psychological pressure on college and university students in India through cluster sampling.
The students responded (
= 209) to an online questionnaire following the Generalized Anxiety Disorder Scale (GAD-7) and Hamilton Anxiety Rating Scale (HAM-A) with some other basic information.
According to GAD-7 scoring, we found the respondent students had severe anxiety (1.44%), moderately severe anxiety (14.35%), moderate anxiety (36.36%) and mild anxiety (47.85%). Following HAM-A scoring, anxiety level among the students could be scaled as severe (0.96%), high (4.31%), moderate (13.40%) and mild anxiety (34.93%) level. Age of the students was a confounding factor (
= 0.049, HAM-A) of experiencing anxiety, students <20years of age were more anxious. We found female students to be more anxious than the males following the HAM-A scoring tool. Academic delays (R
= 0.996,
= 0.036) and impact on daily life (R
= 0.996,
= 0.117) were positively associated with anxiety symptoms, while social support was marginally correlated (R
= 0.726,
= 0.069) with the anxiety level.
As the study found almost all the students are experiencing anxiety because of the current pandemic situation, continuous observation of psychological health for all is recommended as well as establishing psychological intervention during the preparedness phase.
As the study found almost all the students are experiencing anxiety because of the current pandemic situation, continuous observation of psychological health for all is recommended as well as establishing psychological intervention during the preparedness phase.
The aim of this study was to determine the impact of social distancing, self-isolation and limited access to public spaces during the COVID-19 pandemic on the quality of life and psychological well-being of young people.
The coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus posed a new global challenge in 2020. The new coronavirus emerged locally, but it rapidly spread to all continents and also reached Poland. On 24 March, the Polish Ministry of Health enforced self-isolation measures to contain the transmission of the disease. The new regulations imposed restrictions on civic freedoms, including access to public spaces. These measures significantly affected the daily lives of Polish citizens. Public spaces play a fundamental role in catering to the citizens' basic needs. Access to public spaces is directly correlated with the quality of life, human relations and spontaneous interactions. Young people are highly socially active, and they are frequent users of public spaces. Unived by the absence of direct social interactions which, in their opinion, can be only partially compensated for by remote contact.
COVID-19 has become prevalent in the world since December 2019. The further prevalence of the disease can be prevented by correct management of society and increasing knowledge, practices, and attitudes of the people. The present research aimed to evaluate the knowledge, attitudes, and preventive behaviors of people in Hormozgan in the south of Iran toward COVID-19.
The present cross-sectional research was conducted over 2months (March 2020-April 2020). The online questionnaire comprised four sections demographic information, knowledge, attitude, and behavior toward COVID-19. Knowledge included 36 items, attitude eight items, and behavior ten items. The collected data were analyzed statistically using SPSS ver. 22. The split-half method was used to test the reliability of knowledge and the estimated value was 0.84. That of attitude and behavior was estimated via Cronbach's alpha and was found to be 0.81 and 0.75, respectively.
A total number of 2024 participants with an average age of 33.94years took part in this research. Of all participants, 64.4% were female. According to the results, 65.8% enjoyed a good level of knowledge and 34.2% enjoyed an average level. In addition, 63.2% demonstrated a good attitude and 36.8% an average level. A large percentage of participants (90.6%) had good practices and only 9.4% had an average level of practices.
The present findings show that participants had a relatively good level of knowledge, positive attitude, and good behavior concerning COVID-19.
The present findings show that participants had a relatively good level of knowledge, positive attitude, and good behavior concerning COVID-19.
One of the ways to manage the current coronavirus disease 2019 (COVID-19) pandemic is to monitor the public knowledge, risk perceptions, adherence to preventive measures, and level of preparedness behaviors. This is important in resource-limited countries. This study determined the knowledge and perception regarding COVID-19; adherence to COVID-19 preventive measures; as well as predictors of self-perceived risk of contracting COVID-19 among Nigerian adults.
A cross-sectional study was conducted among Nigerian adults ≥18years using an online survey. A convenience sampling method was utilized to recruit a total of 1022 study participants. The participants were recruited using the authors' social media networks. Data were analyzed using descriptive and inferential statistics at a 5% level of statistical significance.
Generally, a high proportion of respondents had correct knowledge about COVID-19. However, only approximately half (49.8% and 49.9%) had correct knowledge that obesity was a risk factor for COVID-19 and that antibiotics cannot be used to treat COVID-19.
Homepage: https://www.selleckchem.com/products/mmp-9-in-1.html
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