Notes

Anti-microbial Biodegradable Meals Packaging Depending on Chitosan and Metal/Metal-Oxide Bio-Nanocomposites: An evaluation.
Unintentional injuries declined progressively from baseline until the end of the study in both the interventional arm (from 52.9% to 2.5%) and control arm (from 44.7% to 32%) [AOR (95% CI) 0.458 (0.405 - 0.518); P value <0.0001]. The decline in incidence of injuries in the interventional arm was higher than that in the control arm (50.4% vs 12.7%; P <0.0001).

School based educational intervention using child safety and injury prevention modules is effective in reducing unintentional injuries among school children over a 10-month period.
School based educational intervention using child safety and injury prevention modules is effective in reducing unintentional injuries among school children over a 10-month period.
Child-To-Child Approach is an innovative strategy for preventing and reducing the morbidity and mortality burden of unintentional childhood injuries.

To test effectiveness of Child-To-Child Approach in preventing unintentional childhood injuries and their consequences.

Community-based non-randomized cluster-controlled trial of parallel design.

397 children and adolescents.

Eldest literate adolescent of selected families of intervention area were trained on prevention of injuries. They were to implement the knowledge gained to prevent injuries in themselves and their younger siblings and also disseminate this knowledge to other members of their families.

Data was collected from both intervention and control areas during pre- and post-intervention phases on the magnitude of injuries, time for recovery from injuries, place for seeking treatment, cost of treatment, knowledge and practice of participants and their families regarding injuries.

During post-intervention phase, the intervention group experienced a significant reduction in incidence of injuries, increased preference for institutional treatment of injuries and increased knowledge and practice regarding injuries, in comparison to its pre-intervention data and data of the control group in post-intervention phase. Total time for recovery and cost of treatment for injuries also decreased in intervention group in post-intervention phase, though differences were not statistically significant.

Child-To-Child Approach is effective in reducing childhood injuries, improving choice of place for seeking treatment, increasing knowledge of participants, improving family practices regarding prevention of injuries and reducing expenditure on treatment of childhood injuries.
Child-To-Child Approach is effective in reducing childhood injuries, improving choice of place for seeking treatment, increasing knowledge of participants, improving family practices regarding prevention of injuries and reducing expenditure on treatment of childhood injuries.There is a lack of clarity regarding management of COVID-19 infection in children. This review aims to summarize the key clinical presentations and management of Pediatric COVID-19. The Medline database was searched for seminal articles and guidelines on COVID-19 presentation and management in children less than 18 years of age. COVID-19 has a lower incidence (1-5% of reported cases worldwide), causes milder disease with lower need for intensive care admission and lower mortality rate (0-0.7%) in children compared with adults. Multisystem inflammatory syndrome is a rare but severe complication in children. Majority of patients require supportive care including adequate hydration, nutrition and antipyretics. Natural Product Library high throughput Supplemental oxygen therapy should be given in moderate to severe cases with all precautions to prevent air-borne COVID-19 spread. Steroids may be helpful in severe cases. Anticoagulation is indicated in moderate to severe cases with risk factors. More data on the efficacy and safety of antivirals and immunomodulators in children is needed.
To evaluate if Healthcare workers (HCWs) at the frontline of COVID 19 response in a pediatric hospital are at an increased risk of acquiring SARS-Cov-2.

The Hospital Infection Control Committee (HICC) and virology testing records were combined to identify SARS-Cov-2 positive HCWs and study the transmission dynamics of COVID-19 over 6 months.

COVID 19 cases in our HCWs cohort rose and declined parallel to community cases. Forty two out of 534 HCWs (8%) were SARS-Cov-2 positive with no fatalities. No clinical staff in the special COVID ward or ICU was positive. Significant proportion of non-clinical staff (30%) were SARS-Cov-2 positive. About 70% of SARS-Cov-2 positive staff had likely community acquisition, with a significant proportion having travelled by public transport or having a contact history with a positive case in the community. Twenty four percent of positive staff were asymptomatic and detected positive on re-joining test.

Sustained transmission of SARS-CoV-22 did not occur in our cohort beyond community transmission. Appropriate PPE use, strict and constantly improving infection control measures and testing of both clinical and non-clinical staff were essential methods for restricting transmission amongst HCWs.
Sustained transmission of SARS-CoV-22 did not occur in our cohort beyond community transmission. Appropriate PPE use, strict and constantly improving infection control measures and testing of both clinical and non-clinical staff were essential methods for restricting transmission amongst HCWs.
To compare the efficacy of Epinephrine plus Vasopressin versus Epinephrine plus Placebo in the pediatric intensive care unit (PICU) cardiopulmonary resuscitation (CPR).

Randomized, double-blind controlled clinical trial.

PICU in a tertiary care institute from February 2019 to May 2020.

Children aged one month to 13 years who required CPR during PICU stay. Patients in whom vascular access was not available or return of spontaneous circulation (ROSC) was achieved by defibrillation without Epinephrine were excluded.

Patients were randomized to receive Vasopressin 0.1 mL per kg (=0.8 Unit per kg) or Placebo (0.1 mL per kg normal saline) in addition to Epinephrine (110000) 0.1 mL per kg. The drugs were given as bolus doses every three minutes until the ROSC or up to a maximum of five doses, whichever was earlier.

The primary outcome was the proportion of patients who achieved ROSC. The secondary outcomes were survival rate and functional status (at 24-hour, PICU, hospital, and 90-day post-discharge), need for organ supports, length of stay (PICU and hospital), and adverse effect(s) of the study drugs.
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