Notes

Parosmia, Dysgeusia, along with Language Features Adjustments to an individual with Post-Acute COVID-19 Malady.
Among them, 72 (28.2%) were current users, who had taken tobacco at least once during the past 30 days and 19 (7.5%) were ever users who had taken tobacco but not during the past 30 days. Conclusions The prevalence of tobacco use among our study participants is similar in comparison to that of the general population. Our study shows greater prevalence of the use of a smokeless form of tobacco than the smoked form of tobacco.Ocular cysticercosis occurs rarely and may involve various parts of the eye including subretinal space. We report a case of a 42 years-old female with diminution of vision in the right eye for one month and no vision in the left eye for 10 years. Best corrected visual acuity in the right eye was 5/60. Fundus examination showed whitish round elevated cystic mass temporal to the macula. It was confirmed as a subretinal cyst by Brightness scan and Magnetic Resonance Imaging. The subretinal cyst was removed in toto by pars plana vitrectomy followed by histopathological examination of the cyst which confirmed the diagnosis of cysticercosis. This case report highlights the importance of early diagnosis of subretinal cysticercosis which could threaten the vision in a one-eyed patient. Pars plana vitrectomy could be an effective method for subretinal cyst removal in toto even in a challenging case.Introduction Hip spica with or without prior traction has become a standard treatment for closed isolated femoral shaft fracture in children below six years. The time of hip spica application is not uniform in the existing literature. The aim of this study is to find out the prevalence of complication of early application of one and a half hip spica for femoral shaft fractures in children below six years in a tertiary care hospital. Methods A descriptive cross-sectional study was done among 42 children who were managed with early hip spica application (within 72 hours) for femoral shaft fracture from January 2015 to December 2020 after receiving ethical clearance from Institutional Review Committee. Convenient sampling technique was done. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results Complication was seen in nine (21.4%) (95% Confidence Interval= 9.02-33.84) patients. Skin breakdown from local pressure had the highest prevalence in our study which was documented in three (7.14%) patients who resolved with conservative treatment. Conclusions The prevalence of complication of early application of one and a half hip spica for femoral shaft fractures in children below six years was similar to other studies done in similar setting.
Lead is naturally available toxic heavy metal which is one of the main causes of environmental pollution and produces detrimental effects on health, particularly young children. Lead toxicity has become an emerging global burden of disease varying with the age, socio-economic status, occupation, industrialization, social customs and behaviours. The objective of this study was to find out the baseline blood lead level among children between 8-18 years.

A descriptive study was conducted in Gokarneshwor Municipality, Kathmandu with a total of 160 children between 8-18 years of age from 2018 to 2019 after taking ethical approval from Research and Institutional Review Committee (Reference number 17-074/075). Informed written consent was taken from the principal along with their respective parents and semi structured questionnaires were asked to students. Sample size was calculated and simple random sampling was done. The data was analyzed using Statistical Package for Social Science version 16. Point estimate at 95% Confidence Interval was calculated along with frequency and descriptive statistics.

The mean blood lead level of the children was 4.39±7.35 µg/dl. Mean hemoglobin being 12.63g/dl; out of 160 children 30 (18.75%) children had blood lead levels. Children with elevated blood lead level had mean haemoglobin level within normal range (13.05gm/dl), however out of 30 children, 8 (27%) had haemoglobin level below normal.

Lead exposure in the children of urban area of Nepal is considerably high as compared to similar studies coducted in similar settings.
Lead exposure in the children of urban area of Nepal is considerably high as compared to similar studies coducted in similar settings.
Dementia is a chronic and progressive syndrome due to disease of brain. Alzhemeir's disease is the most common cause of dementia. There are very few studies regarding prevalence of dementia in Nepal. The objective of this study is to find the prevalence of dementia in 50 years and older patients from the psychiatry out patient department of a tertiary care center.

A descriptive cross-sectional study was done in patients attending to psychiatry outpatient department over one year from May 2020 to April 2021. Ethical approval was taken from the Institutional Review Committee (Reference number 745/077-078). The data were assessed using Statistical Package for Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

Out of 1332 patients, 52 (3.9%) (95% Confidence Interval=2.86-4.93) patients had dementia in which 30 (57.7%) are male while 22 (42.3%) are female. Mean age of study population is 70.12±11.21 with age range of 50 years to 88 years. We found 29 (55.8%) moderate, 18 (34.6%) severe and 5 (9.6%) mild type of dementia. We had 34 (65.3%) Alzheimer's followed by 16 (30.8%) vascular and 2 (3.9%) others types of dementia.

This study concludes that the prevalence of dementia in 50 years and older patients is similar in comparison to other studies done in similar settings.
This study concludes that the prevalence of dementia in 50 years and older patients is similar in comparison to other studies done in similar settings.Silent myocardial infarction or unrecognized myocardial infarction has increased prevalence in elderly population with increased cardiovascular risk factors. However, its prevalence in COVID-19 patients is not well-known. A 77-year-old Caucasian male with COVID-19 pneumonia, presented with silent ST-segment elevation myocardial infarction, diabetic ketoacidosis and multiorgan failure. He underwent cardiac catheterization and drug eluting stent placement in the ostial right coronary artery with safety protocol. He was discharged to extended-care-facility in stable condition. This is a first case report of silent ST-segment elevation myocardial infarction in a patient presenting with COVID-19. In patients with COVID-19, acute myocardial infarction should be ruled out even when asymptomatic, especially in older patients. Prompt intervention using safety protocol is life-saving.
Once a patient is diagnosed with COVID-19 infection, they are required to stay in isolation for some period of time without any social interaction whether be at home or in a hospital setting. The fear of contagion, stigmatization of COVID-19, the social isolation and fear of disease complication has undeniably brought lots of stress and other mental health problems among the infected patients. The main aim of this study is to find the prevalence of anxiety among patients staying in the isolation ward of a tertiary care center.

This was a descriptive cross-sectional study conducted among 147 COVID-19 patients admitted in the isolation ward of a tertiary care center in Nepal from 20 June to 25 July 2021. Ethical approval was taken from Nepal Health Research Council (Reference number 3546). Convenient sampling method was used. Analysis of the data was done using Microsoft Excel and Software Statistical Package for Social Sciences version 26.0. Point estimate at 95% Confidence Interval was done and frequency and percentage were calculated.

Out of 147 participants, 29 (19.74.%) (95% Confidence Interval= 13.31-26.17) experienced some form of anxiety symptoms during their stay in isolation.

Anxiety among COVID-19 patients in this study is similar to other studies done in similar settings. Anxiety among COVID-19 patients is quite high as compared to non COVID-19 patients, therefore assessment of mental health conditions like anxiety, insomnia, depression in patients admitted with COVID-19 should be performed along with the management of physical symptoms.
Anxiety among COVID-19 patients in this study is similar to other studies done in similar settings. Anxiety among COVID-19 patients is quite high as compared to non COVID-19 patients, therefore assessment of mental health conditions like anxiety, insomnia, depression in patients admitted with COVID-19 should be performed along with the management of physical symptoms.Introduction Vitamin D deficiency is one of the common disorders prevalent among both developed and developing countries. Irritable Bowel Syndrome has been linked to many diseases and conditions, one of them being Vitamin D deficiency. To the best of our knowledge, no study of vitamin D deficiency status has been done yet in Nepalese setup. This study aims to find out the prevalence of low levels of Vitamin D in patients with Irritable Bowel Syndrome attending the outpatient department of a tertiary care hospital. Methods This descriptive cross-sectional study was conducted in patients with Irritable Bowel Syndrome attending the outpatient department of a tertiary care hospital in Kathmandu, Nepal between November 2020 and July 2021. Ethical approval was taken from the Institutional Review Committee of Nepal Medical College and Teaching Hospital (Ref No 027-077/078). Convenient sampling was done. The collected data was entered and analyzed in Microsoft Excel. Pexidartinib supplier Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results Out of a total of 71 patients with Irritable Bowel Syndrome, the prevalence of low levels of vitamin D was 44 (61.97%) (95% Confidence Interval= 50.67-73.26). Out of the patients with low vitamin levels, insufficiency was seen in 23 (52.27%) and deficiency was seen in 21 (47.72%). Conclusions Our study found the prevalence of low Vitamin D levels among patients with Irritable Bowel Syndrome to be lower when compared to other studies.
Chronic Kidney Disease is an independent risk factor for pneumonia. The risk of hospitalization, Intensive Care Unit and ventilator requirement, in-hospital death is high in pneumonia patients with chronic kidney disease. This study aims to find the prevalence of pneumonia in patients with chronic kidney disease admitted to nephrology department of a tertiary care center.

A descriptive cross-sectional study was conducted among all the hospital records of pneumonia patients with Chronic Kidney Disease admitted to the Nephrology department between April 2019 and April 2021. Ethical clearance was obtained from the Institutional Review Committee of same institute (Reference number 0505202106). Statistical Package for the Social Sciences version 20 was used for analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

Of the total 407 patients with Chronic Kidney Disease, 78 (19.1%) (95% Confidence Interval= 15.28-22.92) had pneumonia. Among the 78 pneumonia patients, 17 (21.
My Website: https://www.selleckchem.com/products/pexidartinib-plx3397.html