Notes

Allergic along with non-allergic symptoms of asthma phenotypes along with experience pollution.
80 mm, and the average shaft error was less than 0.50 mm. The dosimetric differences between manual reconstruction and automatic reconstruction were 0.29% for high-risk clinical target volume (HR-CTV) D
, and less than 2.64% for organs at risk D
at a scenario of doubled maximum shaft error.

We proposed a deep learning-based reconstruction method to localize Fletcher applicator in three-dimensional CT images. The achieved accuracy and efficiency confirmed our method as clinically attractive. It paves the way for the automation of brachytherapy treatment planning.
We proposed a deep learning-based reconstruction method to localize Fletcher applicator in three-dimensional CT images. The achieved accuracy and efficiency confirmed our method as clinically attractive. It paves the way for the automation of brachytherapy treatment planning.
To evaluate the dosimetry of a six-channel high-dose-rate (HDR) applicator for treatment of esophageal cancer with respect to lateral directionality and heterogeneous media.

A computed tomography (CT)- and magnetic resonance imaging (MRI)-compatible esophageal applicator consisting of 2 inflatable portions (anchor and therapeutic balloons) with 6 longitudinal treatment catheters equally spaced circumferentially was constructed. Treatment plans were prepared using Oncentra 4.5 for various catheter loadings and target locations and sizes. Calculated dose distributions were compared to measured distributions obtained using film and a water phantom. Balloon inflations with water and with air were tested.

TG-43 dose calculations matched measurements well when inflation balloons were filled with water. When air was used to inflate, model-based dose calculations (TG-186) improved the comparison with measurement. Several cases with simulated ring targets demonstrated better dose conformity to non-uniform targets compared to a single central catheter. Additionally, the use of this applicator compared to a single catheter, gave rise to considerable improvement in sparing non-target tissue.

Lateral dose modulation is achievable with the applicator described in this work. The use of TG-186 dose calculation made a small improvement in heterogeneous media.
Lateral dose modulation is achievable with the applicator described in this work. The use of TG-186 dose calculation made a small improvement in heterogeneous media.
Post-mastectomy radiation therapy significantly reduces locoregional recurrence rates, which can be achieved with external beam radiotherapy delivered to chest wall, followed by scar irradiation either by electron or high-dose-rate (HDR) mould brachytherapy. The present study evaluates dosimetric advantage of Acuros
BV, a TG-186 MBDCA, over TG-43 formalism using
Ir source for HDR brachytherapy in chest wall scar boost using catheter flap.

A total of 25 patients, free of cardiac and pulmonary co-morbidities, who met the inclusion criteria were involved in the study. Catheter flap made of silicon with 20 channels was used to deliver a total dose of 7.5 Gy/3 fx by HDR surface mould brachytherapy to delineated scar volume. Plan was optimized with iterative method to obtain desired results with TG-43 formalism, followed by Acuros
BV (GBBS algorithm) without altering dwell positions or time. The two algorithm plans were analyzed qualitatively and quantitatively with dose-volume histograms.

The mean D
CTV-HDR_evl coverage decreased by 1.16% compared to TG-43, and near-maximum dose decreased by 8.18% (
= 0.000), mean D
dose to CTV-HDR_evl, and mean D
dose was lesser by 6.25% (
= 0.000) and 10.82% (
= 0.000), respectively, compared to TG-43. Heart D
showed significant results, whereas D
(cGy) revealed very significant difference. A 5 mm thick skin contour showed statistically significant results (
= 0.000) for V
and V
.

The presented data showed how Acuros
BV, algorithm-based calculation in scar boost irradiation of breast, accounting for a mass density of the medium and scatter condition, considered actual dose prediction in a medium.
The presented data showed how Acuros® BV, algorithm-based calculation in scar boost irradiation of breast, accounting for a mass density of the medium and scatter condition, considered actual dose prediction in a medium.
To dosimetrically compare high-dose-rate interstitial brachytherapy (HDR-BT) with volumetric-modulated arc therapy (VMAT) for tumor bed boost, following breast conservative treatment.

50 patients with early-stage breast cancer who underwent breast conservation surgery, followed by either HDR-BT (
= 25) of 15 Gy in 6 fractions over a period of 3 days, or VMAT dose of 16 Gy in 8 fractions (
= 25) for tumor bed boost, were retrospectively reviewed. All patients received whole breast irradiation of 46 Gy in 23 fractions. Dosimetric parameters for organs at risk (OARs), including ipsilateral and contralateral lungs, heart, contralateral breast, skin, and ribs, were evaluated with the help of dose-volume histograms (DVH).

Heart sparing was similar in both modalities (left-sided breast irradiation, HDR-BT D
20.5% vs. VMAT 30.2%,
-value = 0.243; right-sided breast irradiation, D
6.5% vs. 4.4%,
-value = 0.165). Left-sided cases received higher dose to heart compared to right-sided patients. selleck Interstitial brachytherapy resulted in significantly less dose to contralateral breast (D
4.3% vs. 9.6%,
-value < 0.0001), ipsilateral lung (D
27.6% vs. 73.2%,
-value < 0.0001), contralateral lung (D
4.2% vs. 14.5%,
-value < 0.0001), ribs (D
24.1% vs. 41.2%,
-value < 0.0001), and skin (D
77.3% vs. 95%,
-value < 0.0001).

HDR-BT-based tumor bed boost irradiation results in significantly lower doses to most organs at risk with similar heart sparing compared to VMAT.
HDR-BT-based tumor bed boost irradiation results in significantly lower doses to most organs at risk with similar heart sparing compared to VMAT.
American Brachytherapy Society (ABS) guidelines recommend using a 3-5 cm active length (AL) when treating vaginal cuff (VC) in adjuvant setting of endometrial cancer (EC). The purpose of this study was to evaluate local control and toxicity, using an AL of 1 or 2 cm and immobilization with a traditional table-mounted (stand) or patient-mounted (suspenders) device.

Between 2005 and 2019, 247 patients with EC were treated with adjuvant high-dose-rate vaginal cuff (HDR-VC) brachytherapy with or without external beam radiation (EBRT). Treatment was prescribed to a 0.5 cm depth, with an AL of 1 or 2 cm, using stand or suspenders. VC boost after EBRT was typically administered with 2 fractions of 5.5 Gy, while VC brachytherapy alone was typically applied with 3 fractions of 7 Gy or 5 fractions of 5.5 Gy.

The combination of suspender immobilization and an AL of 2 cm (
= 126, 51%) resulted in 5-year local control of 100%. An AL of 2 cm compared to 1 cm correlated with better local control (99.1% vs. 88.5%,
= 0.
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