Notes

Role involving multimodal pain relievers within post-operative analgesic dependence on robotic aided significant prostatectomy.
The present research explores decision making in multitasking, investigating how people make optimal decisions between tasks. Empirical evidence suggests that difficulties in task performance (i.e., response conflict within a task) can bias decision making. Here we investigate whether also conflict between task representations can tune choices away from conflict-associated tasks. NSC 27223 ic50 Using a combined forced/free-choice task-switching design, we tested whether task conflict that arises because of proactive interference of previously activated tasks biases task choice. We compared free-choice decisions between 3 tasks after forced-choice sequences that instigated either high task conflict (task sequences of type ABA, in which persisting inhibition needs to be overcome because one switches back to a just-abandoned task) or low task conflict (task sequences of type CBA). Results of 2 experiments (N = 16; N = 32, preregistered) showed that participants were more likely to switch away from the previously performed task after high than after low task conflict. Furthermore, participants preferably selected the task that suffered least from task conflict and/or proactive interference. In addition, a third experiment (N = 32) confirmed that this bias in task selection could not be explained in terms of randomness heuristics. These results suggest a close link between decision making and performance in multitasking. (PsycInfo Database Record (c) 2020 APA, all rights reserved).In a world where ideas flow freely across multiple platforms, people must often rely on others' advice and opinions without an objective standard to judge whether this information is accurate. The present study explores the hypothesis that an individual's internal decision confidence can be used as a signal to learn the accuracy of others' advice, even in the absence of feedback. According to this "agreement-in-confidence" hypothesis, people can learn about an advisor's accuracy across multiple interactions according to whether the advice offered agrees with their own initial opinions, weighted by the confidence with which these initial opinions are held. We test this hypothesis using a judge-advisor system paradigm to precisely manipulate the profiles of virtual advisors in a perceptual decision-making task. We find that when advisors' and participants' judgments are independent, people can correctly learn advisors' features, like their accuracy and calibration, whether or not objective feedback is available. However, when their judgments (and thus errors) are correlated-as is the case in many real social contexts-predictable distortions in trust can be observed between feedback and feedback-free scenarios. Using agent-based simulations, we explore implications of these individual-level heuristics for network-level patterns of trust and belief formation. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Response errors often cause individuals to slow down their subsequent reactions (posterror slowing [PES]). Despite intensive investigations on PES, the adaptive nature of PES remains unresolved. Here, we systematically examined this issue by manipulating response-stimulus intervals (RSIs) and examining their influence on behaviors and neural dynamics of PES. Behavioral and electrophysiological (EEG) measures were recorded while male and female human participants performed a four-choice flanker task as RSIs were manipulated. Behaviorally, PES showed maladaptive features at short RSIs but some adaptive features at long RSIs. EEG results indicated that RSIs did not affect basic error-related processing, indexed by the same pattern in the contrasts between flanker errors and correct responses on the error-related negativity (ERN), error positivity (Pe), or theta band, no matter at short or long RSIs. However, RSIs significantly influenced postflanker error attentional adjustment, motor inhibition, and sensory sensitivity. At short RSIs, compared with postcorrect trials, postflanker error trials elicited larger beta band power and smaller P1 amplitude but did not affect alpha band power, suggesting that motor processing was inhibited, and subsequent sensory processing was impaired, but no attentional adjustment occurred. By contrast, at long RSIs, postflanker error trials led to smaller alpha and beta band power but did not affect P1 amplitude, indicating that attentional adjustment but not motor inhibition occurred, and sensory processing was not impaired. Together with behavioral results, the current study demonstrated that PES was adaptive at long RSIs but maladaptive at short RSIs. We further discuss the role of central resources in the adaptability of PES. (PsycInfo Database Record (c) 2020 APA, all rights reserved).The current study further examined the effect of the muscarinic acetylcholine antagonist, scopolamine, on the Context Preexposure Facilitation Effect (CPFE; Robinson-Drummer, Dokovna, Heroux, & Stanton, 2016). In the CPFE, context representations formed during the preexposure phase are retrieved and associated with immediate shock during the training phase and expressed as freezing during a 24-hr retention phase. Scopolamine abolished postshock and retention freezing when administered systemically prior to preexposure (Experiment 1A) or immediate-shock training (Experiment 1B). Pretraining infusion of scopolamine into dorsal hippocampus (dHPC) disrupted both postshock and retention freezing (Experiments 2A) and retention freezing when the postshock freezing test was omitted (Experiment 2B) but did not alter expression of freezing behavior to an auditory fear stimulus (Experiment 2C). Finally, pretraining scopolamine infusion into ventral hippocampus (vHPC) also abolished postshock and retention test freezing (Experiment 3). These findings suggest similar roles for muscarinic receptor activity in both the dHPC and vHPC in the CPFE. This study advances understanding of the neurobiology of the CPFE by showing that context-shock associations are not learned following disruption of the cholinergic and/or hippocampal function on either the preexposure or training day. Existing theories of the CPFE (Rudy, 2009) have inferred this effect based on impaired 24-hr retention observed in previous studies (Matus-Amat, Higgins, Barrientos, & Rudy, 2004; Robinson-Drummer et al., 2016). However, the present study is the first to demonstrate it directly by including a postshock freezing measure. Further, this study is the first to identify vHPC as another important region necessary for context-shock learning during the CPFE paradigm. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
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