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Among patients with high distress and low relationship quality, a 1 SD increase in spousal influence predicted a difference roughly equivalent to the difference between the sample mean CV and a CV in the unstable glycemia range. Conclusions This was the first study to examine moderators of the link between spousal influence and glycemic control in diabetes. A large effect was found for glucose variability, but not mean levels. These novel results highlight the importance of intimate relationships in diabetes management.A dataset of knee kinematics in healthy, uninjured adults is needed to serve as a reference for comparison when evaluating the effects of injury, surgery, rehabilitation, and age. Most currently available datasets that characterize healthy knee kinematics were developed using conventional motion analysis, known to suffer from skin motion artifact. More accurate kinematics, obtained from bone pins or biplane radiography, have been reported for datasets ranging in size from 5 to 15 knees. The aim of this study was to characterize tibiofemoral kinematics and its variability in a larger sample of healthy adults. Thirty-nine knees were imaged using biplane radiography at 100 images/s during multiple trials of treadmill walking. Multiple gait trials were captured to measure stance and swing phase knee kinematics. 6DOF kinematics were determined using a validated volumetric model-based tracking process. A bootstrapping technique was used to define average and 90% prediction bands for the kinematics. The average ROM during gait was 7.0 mm, 3.2 mm, and 2.9 mm in AP, ML and PD directions, and 67.3°, 11.5° and 3.7° in FE, IE, and AbAd. Continuous kinematics demonstrated large inter-knee variability, with 90% prediction bands spanning approximately ±4 mm, ±10 mm, and ±5 mm for ML, AP, and PD translations and ±15°, ±10°, and ±6° in FE, IE, and AbAd. This dataset suggests substantial variability exists in healthy knee kinematics. This study provides a normative database for evaluating knee kinematics in patients who receive conservative or surgical treatment.Background Self-monitoring is a key component of behavioral weight loss (BWL) interventions. Past research suggests that individuals may avoid self-monitoring in certain contexts (e.g., skipping self-weighing after higher-than-usual calorie intake). However, no studies have attempted to quantify individuals' inclination to avoid information about their weight control ("weight-related information avoidance"; WIA) or prospectively examined its implications for treatment engagement and outcomes in BWL programs. Purpose Characterize WIA using a validated questionnaire among adults enrolled in BWL treatment and examine whether WIA prospectively predicts self-monitoring adherence, session attendance, treatment discontinuation, or weight loss. Methods Participants (N = 87; MBMI = 34.9 kg/m2, 83% female) completed a measure of WIA prior to starting a 12 week, group-based BWL intervention. Participants were given digital self-monitoring tools and instructed to self-monitor their food intake daily, physical activity daily, and body weight weekly (Weeks 1-10) and then daily (Weeks 11-12). Session attendance and treatment discontinuation were recorded. Weight was measured in-clinic pretreatment and posttreatment. Results While mean WIA was low (M = 2.23, standard deviation [SD] = 0.95; potential scale range 1-7), greater WIA predicted poorer attendance (r = -.23; p = .03) and poorer self-monitoring of physical activity (r = -.28; p = .009) and body weight (r = -.32; p = .003). WIA did not predict food monitoring (p = .08), treatment discontinuation (p = .09), or 12 week weight loss (p = .91). Conclusions Greater WIA, as assessed via a brief questionnaire, may place individuals at risk for poorer self-monitoring and treatment engagement during BWL. Further research on the implications of WIA in the context of weight management is warranted, including evaluation of correlates, moderators, and mechanisms of action of WIA. Clinical trial registration NCT03337139.The stress-induced c-Jun N-terminal kinase (JNK) controls microtubule dynamics by enhancing both microtubule growth and rescues. Here, we show that upon cell stress, JNK directly phosphorylates the microtubule rescue factor CLIP-170 in its microtubule-binding domain to increase its rescue-promoting activity. Phosphomimetic versions of CLIP-170 enhance its ability to promote rescue events in vitro and in cells. Furthermore, while phosphomimetic mutations do not alter CLIP-170's capability to form comets at growing microtubule ends, both phosphomimetic mutations and JNK activation increase the occurrence of CLIP-170 remnants on the microtubule lattice at the rear of comets. As the CLIP-170 remnants, which are potential sites of microtubule rescue, display a shorter lifetime when CLIP-170 is phosphorylated, we propose that instead of acting at the time of rescue occurrence, CLIP-170 would rather contribute in preparing the microtubule lattice for future rescues at these predetermined sites.Objective To describe the socioeconomic, demographic and obstetric profile of pregnant women with Gestational Hypertensive Syndrome. Methods A descriptive and correlational study, conducted in Maternity School Assis Chateaubriand, with 120 pregnant women, through a questionnaire analyzed by descriptive and analytical statistics. Results most women had chronic hypertension (60.83%). Regarding the socioeconomic and demographic profile, most pregnant women had a mean age of 30.9 ± 6.9 years, were Catholic, brown skin color, employed, in stable unions, complete high school education, and income of up to R$ 954.00. Regarding the obstetric profile, their Body Mass Index was up to 66, slightly elevated blood pressure, an average of five prenatal consultations, two pregnancies, one delivery and no abortions. Women with chronic hypertension were older (p = 0.0024), had lower gestational age (p = 0.0219) and a higher number of abortions (p = 0.0140). Conclusions Pregnant women are overweight/obese, with a mean age of 30.9 years and are socially vulnerable. Pregnant women with chronic hypertension are older and have a higher number of abortions.Objective To identify the primary bandages recommended in the literature to dress the wounds of people with pemphigus vulgaris and to describe the positive or negative repercussions related to these bandages. Method Integrative literature review, using the descriptors "dressing", "nursing care", "nursing", "skin diseases / vesiculobollous" and "pemphigus"; inclusion criteria articles that address primary bandages for pemphigus vulgaris skin lesion dressing; published between 2010 and 2017; in Portuguese, English or Spanish; indexed in BDENF, LILACS, PubMed, and/or Scopus. Results eight articles were selected, seven had evidence levels 4 and 5 and one had evidence level 3. The primary bandages covered were silver gel, hydrocolloid, hydrogel, silver-containing hydrofiber, antibiotics, sterilized vaseline, corticoid, and vitamin E ointment Conclusion Sterile gauze with vaseline, prepared according to protocol, was the bandage presented in the study with the most significant level of evidence.Objective To validate a multiprofessional protocol for the care of patients with delirium admitted to an intensive care unit. Method Methodological study with the purpose of confirming with experts the care recommendations proposed in the protocol. For the content validation process, the content validity index of ≥ 0.90 was considered. Results Of the 48 recommendations submitted to content validation, only four did not reach consensus through the content validity index. The multiprofessional protocol for patients with delirium in the intensive care unit included care related to the diagnosis of delirium, pause in sedation, early mobilization, pain management, agitation and delirium, cognitive guidance, sleep promotion, environmental interventions, and family participation. Conclusion The multiprofessional protocol qualifies the care provided to critically ill patients with delirium, improving clinical outcomes.Objective To understand the experiences and care practices of mothers of children with congenital Zika syndrome. Methods A qualitative study with collection held in Feira de Santana - Bahia, between September and November 2017, from in-depth interviews and Story-Drawing with 11 family members of children, using thematic content analysis. Results Mothers take care from experiences with health professionals and groups of mothers. They reorganize themselves in order to optimize time, streamline domestic activities, teach family members, and navigate care spaces. this website They experience the routine organizing the home, taking care of the children and, specifically, the child with syndrome, referring to bedtime; giving a shower; changing diapers; feeding; playing; and, stimulating, actions mediated by intense crying and environmental preparation. Conclusion The experiences are unique and exceptional, conforming the social representation of the mothers as a group, the "mothers of micro", an aspect that differs from other experiences.Objective To describe the family dynamics and the social support network for families of children with special needs of multiple, complex and continuous care. Methods A descriptive study of a qualitative approach, carried out in Maringá - PR, having as theoretical and methodological reference the Calgary Model of Family Assessment (CMFA). Data was collected through semi-structured audio-video interviews, carried out in the homes, together with 11 family caregivers of 13 children. Results Data is presented in the following categories structural, developmental and functional evaluation, which show the changes in the family routine and the needs for the adjustment of the roles of its members, in order to better implement the care at home. Conclusions Using the CMFA made it possible to identify and understand the composition, fragilities and potentialities of the family, as well as the relationships among its members and rearrangements to better enable care at home. This information favors interventions congruent with the needs of these families.Objective To verify the association between individual, work-related and organizational factors with adherence to standard precautions. Method Cross-sectional study, carried out from January to June 2016 with 602 nursing workers from a university hospital. Ten Likert-type psychometric scales were used, with 57 items, organized in three domains individual, work-related and organizational factors. Data were analyzed with descriptive and inferential statistics. Results The adherence to the standard precautions obtained a mean intermediate score (4.30 ± 1.03) and a positive correlation with the Risk Personality Scales (r = 0.136, p less then 0.0001), Prevention Efficacy (r = 0.109 , p less then 0.0001), Obstacles to follow the precautions (r = 0.394, p less then 0.0001), PPE availability (r = 0.189 p less then 0.0001), Safety Climate (r = 0.325, p less then 0 , 0001) and Training on Prevention of Occupational Exposure (r = + 0.308, p less then 0.0001). Conclusion Adherence to standard precautions is associated with individual, work-related, and organizational factors.
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