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Widely available and reliable testing for SARS-CoV-2 is essential for the public health response to the COVID-19 pandemic. We estimated the diagnostic performance of reverse transcription PCR (RT-PCR) performed on saliva and the SD Biosensor STANDARD Q antigen test performed on nasopharyngeal swab compared to the reference standard, nasopharyngeal swab (NP) RT-PCR. We enrolled participants living and/or seeking care in health facilities in North Lima, Peru from November 2020 to January 2021. Consenting participants underwent same-day RT-PCR on both saliva and nasopharyngeal swab specimens, antigen testing on a nasopharyngeal swab specimen, pulse oximetry, and standardized symptom assessment. We calculated sensitivity, specificity, and predictive values for the nasopharyngeal antigen and saliva RT-PCR compared to nasopharyngeal RT-PCR. Of 896 participants analyzed, 567 (63.3%) had acute signs/symptoms of COVID-19. The overall sensitivity and specificity of saliva RT-PCR were 85.8% and 98.1%, respectively. Amonsor STANDARD Q antigen test performed on nasopharyngeal swab had 80% sensitivity.Within the mature field of Anderson transitions, the critical properties of the integer quantum Hall transition still pose a significant challenge. Numerical studies of the transition suffer from strong corrections to scaling for most observables. In this Letter, we suggest to overcome this problem by using the longitudinal conductance g of the network model as the scaling observable, which we compute for system sizes nearly 2 orders of magnitude larger than in previous studies. We show numerically that the sizable corrections to scaling of g can be accounted for in a remarkably simple form, which leads to an excellent scaling collapse. Surprisingly, the scaling function turns out to be indistinguishable from a Gaussian. We propose a cost-function-based approach and estimate ν=2.609(7) for the localization length exponent, consistent with previous results, but considerably more precise than in most works on this problem. Extending previous approaches for Hamiltonian models, we also confirm our finding using integrated conductance as a scaling variable.We present an experimental realization of a biased optical periodic potential in the low friction limit. The noise-induced bistability between locked (torsional) and running (spinning) states in the rotational motion of a nanodumbbell is driven by an elliptically polarized light beam tilting the angular potential. By varying the gas pressure around the point of maximum intermittency, the rotational effective diffusion coefficient increases by more than 3 orders of magnitude over free-space diffusion. These experimental results are in agreement with a simple two-state model that is derived from the Langevin equation through using timescale separation. Our work provides a new experimental platform to study the weak thermal noise limit for diffusion in this system.An analytic formula is given for the three-point energy correlator at leading order in maximally supersymmetric Yang-Mills theory (N=4 sYM). This is the first analytic calculation of a three-parameter event shape observable, which provides valuable data for various studies ranging from conformal field theories to jet substructure. The associated class of functions define a new type of single-valued polylogarithms characterized by 16 alphabet letters, which manifest a D_6×Z_2 dihedral symmetry of the event shape. With the unexplored simplicity in the perturbative structure of the three-point energy correlator, all kinematic regions including collinear, squeezed and coplanar limits are now available.We report the first results of a search for leptophobic dark matter (DM) from the Coherent-CAPTAIN-Mills (CCM) liquid argon (LAr) detector. An engineering run with 120 photomultiplier tubes (PMTs) and 17.9×10^20 protons on target (POT) was performed in fall 2019 to study the characteristics of the CCM detector. The operation of this 10-ton detector was strictly light based with a threshold of 50 keV and used coherent elastic scattering off argon nuclei to detect DM. Despite only 1.5 months of accumulated luminosity, contaminated LAr, and nonoptimized shielding, CCM's first engineering run has already achieved sensitivity to previously unexplored parameter space of light dark matter models with a baryonic vector portal. With an expected background of 115 005 events, we observe 115 005+16.5 events which is compatible with background expectations. For a benchmark mediator-to-DM mass ratio of m_V_B/m_χ=2.1, DM masses within the range 9 MeV≲m_χ≲50 MeV are excluded at 90% C. L. in the leptophobic model after applying the Feldman-Cousins test statistic. CCM's upgraded run with 200 PMTs, filtered LAr, improved shielding, and 10 times more POT will be able to exclude the remaining thermal relic density parameter space of this model, as well as probe new parameter space of other leptophobic DM models.Beam spray measurements suggest thresholds that are a factor of ≈2 to 15× less than expected based on the filamentation figure of merit often quoted in the literature. In this moderate-intensity regime, the relevant mechanism is forward stimulated Brillouin scattering. Both weak ion acoustic wave damping and thermal enhancement of ion acoustic waves contribute to the low thresholds. Forward stimulated Brillouin scattering imparts a redshift to the transmitted beam. Regarding the specific possibility of beam spray occurring outside the laser entrance holes of an indirectly driven hohlraum, this shift may be the most concerning feature owing to the high sensitivity of crossed-beam energy transfer to the interacting beam wavelengths in the subsequent overlap region.We propose a time-symmetric counterpart of the current in stochastic thermodynamics named the time-symmetric current. This quantity is defined with empirical measures and thus is symmetric under time reversal, while its ensemble average reproduces the amount of the average current. We prove that this time-symmetric current satisfies the fluctuation-response relation in the conventional form but with sign inversion. Remarkably, this fluctuation-response relation holds not only around equilibrium states but also around nonequilibrium stationary states if observed currents stall. The obtained relation also serves as an experimental tool for probing the value of a bare transition rate by measuring only time-integrated empirical measures.Multiparticle azimuthal correlations of prompt D^0 mesons are measured in Pb-Pb collisions at a nucleon-nucleon center-of-mass energy of sqrt[s_NN]=5.02 TeV. For the first time, a four-particle cumulant method is used to extract the second Fourier coefficient of the azimuthal distribution (v_2) of D^0 mesons as a function of event centrality and the D^0 transverse momentum. The ratios of the four-particle v_2 values to previously measured two-particle cumulant results provide direct experimental access to event-by-event fluctuations of charm quark azimuthal anisotropies. These ratios are also found to be comparable to those of inclusive charged particles in the event. However, hints of deviations are seen in the most central and peripheral collisions. To investigate the origin of flow fluctuations in the charm sector, these measurements are compared to a model implementing fluctuations of charm quark energy loss via collisional or radiative processes in the quark-gluon plasma. These models cannot quantitatively describe the data over the full transverse momentum and centrality ranges, although the calculations with collisional energy loss provide a better description of the data.Conventional lattice formulations of θ vacua in the 1+1-dimensional O(3) nonlinear sigma model suffer from a sign problem. Here, we construct the first sign-problem-free regularization for arbitrary θ. Using efficient lattice Monte Carlo algorithms, we demonstrate how a Hamiltonian model of spin-1/2 degrees of freedom on a two-dimensional spatial lattice reproduces both the infrared sector for arbitrary θ, as well as the ultraviolet physics of asymptotic freedom. Furthermore, as a model of qubits on a two-dimensional square lattice with only nearest-neighbor interactions, it is naturally suited for studying the physics of θ vacua and asymptotic freedom on near-term quantum devices. Our construction generalizes to θ vacua in all CP(N-1) models, solving a long-standing sign problem.We demonstrate that the physics of the F model can be approached very closely in a two-dimensional artificial magnetic system. Faraday lines spanning across the lattice and carrying a net polarization, together with chiral Faraday loops characterized by a zero magnetic susceptibility, are imaged in real space using magnetic force microscopy. Our measurements reveal the proliferation of Faraday lines and Faraday loops as the system is brought from low- to high-energy magnetic configurations. They also reveal a link between the Faraday loop density and icelike spin-spin correlations in the magnetic structure factor. Key for this Letter, the density of topological defects remains small, on the order of 1% or less, and negligible compared to the density of Faraday loops. This is made possible by replacing the spin degree of freedom used in conventional lattices of interacting nanomagnets by a micromagnetic knob, which can be finely tuned to adjust the vertex energy directly, rather than modifying the two-body interactions.Symmetric anisotropic interaction can be ferromagnetic and antiferromagnetic at the same time but for different crystallographic axes. We show that the competition of anisotropic interactions of orthogonal irreducible representations can be a general route to obtain new exotic magnetic states. We demonstrate it here by observing the emergence of a continuously tunable 12-layer spatial spin modulation when distorting the square-lattice planes in the quasi-two-dimensional antiferromagnetic Sr_2IrO_4 under in situ shear strain. This translation-symmetry-breaking phase is a result of an unusual strain-activated anisotropic interaction which is at the fourth order and competing with the inherent quadratic anisotropic interaction. Such a mechanism of competing anisotropy is distinct from that among the ferromagnetic, antiferromagnetic, and/or the Dzyaloshinskii-Moriya interactions, and it could be widely applicable and highly controllable in low-dimensional magnets.A search for resonances decaying into a W boson and a radion, where the radion decays into two W bosons, is presented. see more The data analyzed correspond to an integrated luminosity of 138 fb^-1 recorded in proton-proton collisions with the CMS detector at sqrt[s]=13 TeV. One isolated charged lepton is required, together with missing transverse momentum and one or two massive large-radius jets, containing the decay products of either two or one W bosons, respectively. No excess over the background estimation is observed. The results are combined with those from a complementary channel with an all-hadronic final state, described in an accompanying paper. Limits are set on parameters of an extended warped extra-dimensional model. These searches are the first of their kind at the LHC.
Read More: https://www.selleckchem.com/products/wh-4-023.html
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