Notes

Effects of Nanotexture on Electric Profiling regarding Solitary Growth Mobile and also Diagnosis regarding Cancer malignancy via Blood vessels in Microfluidic Stations.
ABC-GOALS is a tool to timely predict the need for admission to ICU in Covid-19.
ABC-GOALS is a tool to timely predict the need for admission to ICU in Covid-19.
To analyze the prevalence of modern contraceptive methods (CM) use in adolescents aged 12 to 19 years in 2012 and 2018-19, and the factors associated with consistent use of modern CM.

Using the Health and Nutrition National Surveys 2012 and 2018-2019 we calculated the outcome variables long-acting reversible contraceptives (LARC) use, dual protection and consistent use of CM. GW0742 We estimated prevalence by sex and adjusted logistic models with consistent use (which is understood as CM use in the first and last sexual relationship) as a dependent variable.

LARC use in last intercourse increased between surveys (4.1 to 6.3%). For women, being older, not having been pregnant, and school attendance increased the likelihood of consistent use. For men, school attendance increases the likelihood while cohabiting, early sexual initiation and having smoked more than 100 cigarettes reduces it.

It is necessary to promote access and consistent use of MC, based on respect for sexual and reproductive rights.
It is necessary to promote access and consistent use of MC, based on respect for sexual and reproductive rights.
Understand what Mexican key stakeholders think about the judicialization of the right to health in Mexico.

30 semi-structured interviews were conducted at different settings in Mexico City with representatives of the judiciary, legislative power, Health Sector (HS), pharmaceutical industry, academia and nongovernmental organizations from May 2017 to August 2018. Interviews were transcribed and analyzed based on different categories of interest.

There are different opinions regarding judicialization of the right to health. Tensions exist between those who see its potential effect as a game changer for the HS and those who perceive it as an illegitimate interference of the judiciary. There is no coordinated strategy between sectors to promote change in the HS.

There are different opinions regarding judicialization of the right to health in Mexico. There are tensions between those who see its potential effect as a game changer for the HS and those who perceive it as an illegitimate interference of the judiciary. Others argue that there is no coordinated strategy between sectors to promote change in the HS. All agree that judicialization in Mexico is a reality.
There are different opinions regarding judicialization of the right to health in Mexico. There are tensions between those who see its potential effect as a game changer for the HS and those who perceive it as an illegitimate interference of the judiciary. Others argue that there is no coordinated strategy between sectors to promote change in the HS. All agree that judicialization in Mexico is a reality.
Available data suggest the important role of ablation of the left atrial posterior wall and epicardial myocardial layers in rhythm control therapy in patients with persistent drug‑refractory atrial fibrillation (AF). However, endocardial ablation is not always effective in transmural substrate modification. The alternative treatment option is minimally invasive hybrid approach (HABL) combining the strengths of surgical and catheter ablation.

This study aimed to assess the periprocedural safety as well as acute and long‑term outcomes of HABL for AF.

This is a retrospective single‑center study of patients who underwent HABL using the minimally invasive transabdominal approach between July 2009 and January 2020. Demographic in‑hospital data and 12‑month follow‑up results were obtained. The number of hospitalizations, cardioversions, re‑ablations, and severe adverse events in a 3‑year period before and after HABL were compared using data from the national healthcare provider.

In total, 158 patients (mean ative therapeutic option especially in patients with persistent AF.Heart failure with preserved ejection fraction (HFpEF) is an increasingly common condition, particularly in the context of the aging of the population. HFpEF is associated with high morbidity, mortality, and rate of heart failure rehospitalization as well as poor quality of life. Previous studies on HFpEF failed to reach a positive outcome. There is currently no approved treatment for HFpEF. The overall PARAGON‑HF trial population showed a 13% reduction in the primary endpoint (cardiovascular death and total heart failure hospitalizations) with sacubitril / valsartan treatment as compared with valsartan, which was of borderline statistical significance. Analyses of the secondary endpoints, including the clinical status, quality of life, and kidney function, imply that sacubitril / valsartan offers benefits compared with valsartan alone. The results of the PARAGON‑HF trial revealed that patients with HFpEF and particular clinical profiles (lower strata of ejection fraction below 57% and female sex), for whom no evidence‑based therapy is available, may benefit from treatment with sacubitril / valsartan. This review article summarizes opinions on the PARAGON‑HF results as well as a mechanistic discussion.Atrial fibrillation (AF) represents the most common arrhythmia and is associated with increased morbidity and mortality generating high social costs. Due to its high prevalence, AF is usually managed not only by cardiologists but also by general practitioners or clinicians in emergency departments. The conventional classification of AF includes "recent‑onset AF" defined as an arrhythmia episode shorter than 48 hours. In patients with a definite duration of AF of less than 24 hours and a very low-risk profile (CHA2DS2VASc of 0 in men and 1 in women), the thromboembolic risk seems to be low, and the standard 4‑week anticoagulation therapy is now regarded as optional treatment. Cardioversion (electrical or pharmacological) in recent‑onset AF represents a valid rhythm control strategy. Electrical cardioversion is usually reserved for hemodynamically unstable patients and performed with biphasic waveform shocks. On the other hand, pharmacological cardioversion is preferred in hemodynamically stable patients. Several antiarrhythmic drugs have been studied so far, but some questions still remain unresolved mainly due to lack of randomized clinical trials and prospective studies. The current guidelines do not uniformly agree on which drug to use for pharmacological cardioversion, and drug preference varies widely in clinical practice. The aim of this narrative review is to sum up and critically evaluate novel evidence regarding recent‑onset AF as well as to provide some practical considerations particularly focused on rhythm control with pharmacological cardioversion.
Valve-sparing aortic root replacement (VSARR) techniques are an alternative to the classic Bentall procedure when aortic root aneurysm is not accompanied by aortic valve stenosis, and the regurgitant aortic valve is amenable to repair.

The aim of the study was to assess long -term outcomes of valve sparing aortic root replacement using the David technique and the Yacoub technique.

A total of 101 consecutive, elective VSARR procedures were performed from January 2010 to April 2020 including 52 David procedures (51.5%) and 49 Yacoub procedures (48.5%). We analyzed mortality, freedom from reoperation, and freedom from aortic valve regurgitation. The analysis was performed for the entire study cohort and for 2 subgroups the David technique and the Yacoub technique.

The mean (SD) age was 50.2 (16.1) years; 90 (89.1%) patients were male. The median (interquartile range [IQR]) EuroScore II was 3.7 (2.7‒5.8). At 1, 5, and 8 years after surgery, survival (SE) was 98% (3%), 91.8% (8%), and 91.8% (8%), respectively, whereas freedom from reoperation (SE) was 100%, 97% (3%), and 97% (3%), respectively. Follow‑up echocardiography performed at a median (IQR) of 18.7 (2.5‒36.7) months postsurgery revealed freedom from aortic valve regurgitation in 90.8% of patients. No significant differences in mortality, freedom from reoperation, and freedom from aortic valve regurgitation were noted between the David and Yacoub subgroups.

VSARR is a safe and effective surgical technique in patients with aortic root aneurysm, as the associated mortality, reoperation rate, and aortic valve regurgitation recurrence are low.
VSARR is a safe and effective surgical technique in patients with aortic root aneurysm, as the associated mortality, reoperation rate, and aortic valve regurgitation recurrence are low.A novel bithiophene-fulleropyrrolidine bisadducts system (bis-Th2PC60 ) was synthesized and electropolymerized by chronoamperometry onto flexible ITO/PET substrates. The resulting semitransparent thin film was characterized by XPS, FT-IR, cyclic voltammetry and optical techniques, confirming the good outcome of the electropolymerization process. AFM investigations permitted to highlight an inherent disordered granular morphology, in which the grain-to-grain separation depends upon the application of bending. The electrical resistance of the thin film was characterized as a function of bending (in the range 0°-90°), showing promising responsivity to low bending angles (10°-30°). The ΔR/R0 variations turn out to be 8 %,16 % and 20 % for bending angles equal to 10°, 20° and 30°, respectively. This study represents a first step towards the understanding of piezoresistive properties in electropolymerized fullerenes-based thin films, opening up applications as bending sensor.Social support is important to optimize bariatric surgery outcomes, but limited tools exist for brief and effective assessment preoperatively. The aims of the study were to determine the extent to which two ratings of social support can predict bariatric surgery outcomes, and to examine any associations between these two methods.In this retrospective study, patients were included for whom the Cleveland clinic behavioral rating system (CCBRS) and Flanagan quality of life scale (FQoLS) scores were obtained as part of their preoperative psychosocial evaluation. They were followed up for 6 to 24 months after bariatric surgery. Linear and logistic regressions were performed with patients' CCBRS and FQoLS scores as independent variables, and percent excess weight loss (%EWL), length of stay (LOS), complications, readmissions and loss to follow-up as dependent variables. The prediction of CCBRS ratings from FQoLS social support items was also evaluated. A total of 415 patients were included in the analysis. There were significant associations between the CCBRS and three of the four relevant FQoLS self-ratings. As CCBRS and FQoLS scores increased, complications decreased significantly. The CCBRS alone additionally predicted decreased length of hospital stay and approached significance for predicting decreased readmission rates. There were no associations between %EWL and behavior ratings. The degree of patients' social support is associated with important bariatric surgery outcomes. It is possible to obtain this valuable information via the administration of brief assessments prior to bariatric surgery.
A vital public health challenge lies in understanding the primary drivers behind excessive weight gain among healthy weight individuals.

To examine if excessive weight and fat gain can be prevented among healthy weight, obesity susceptible children aged 2 to 6 years.

Eligible children were identified based on information on either a high birth weight, maternal pre-pregnancy obesity or maternal low educational level from national registries, and randomized into an intervention group, a control group and a shadow control group. All children with overweight at baseline were excluded from subsequent analysis (n = 196), while healthy weight children were included (n = 926). The intervention was designed to deliver improvements in diet and physical activity habits, optimization of sleep quantity and quality, and reduction of family stress. The average intervention period was 1.3 years.

Intention-to-treat analyses indicated a lower gain in percentage fat mass and a higher gain in fat-free mass in the intervention group compared with the control group.
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