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Supernumerary kidney is an accessory kidney with its own vasculature, collecting-system and encapsulated parenchyma with about 100 cases reported in the literature. However, there is no report of supernumerary kidney associated with horseshoe malformation with ureteric stricture. We report a rare case of 20 months old female admitted with left-sided abdomen lump and mild abdominal pain. During surgery, supernumerary kidney with horseshoe component with grossly-dilated left-sided pelvicalyceal system and proximal 1-cm of left-ureter, distal to which whole of left-ureter was noncanalized, was seen. Right-ureter was normal. Distal dilated part of left-ureter was anastomosed to bladder-dome after excision of strictured segment of left-ureter with placement of nephrostomy.
To evaluate adherence to the American Urologic Association (AUA) best practice statement guidelines regarding antibiotic duration in the perioperative setting for endoscopic urologic surgery. We assessed concordance to these guidelines among adult urologists at a single academic institution and its correlation with postoperative positive urine cultures as it relates to the revised 2019 best practice statement.
We performed a retrospective review of all adult endoscopic ambulatory urologic surgeries performed over an 18-month period by urologists at our institution. Patient demographics, pre- and postoperative urine cultures, operative details, stent or foley use, and antibiotic prescriptions were reviewed. Chi-squared and linear regression analyses were done.
Three hundred thirty patients were included for analysis. Sixty-two percent of patients were prescribed postoperative antibiotics, for an average of 4 days. Trimethoprim/Sulfamethoxazole and fluroquinolones were most often prescribed (43% and 38%, ceipt or duration of antibiotic prescription at the time of surgery, supporting minimal use of antibiotics for most endoscopic cases.
To report our experience in robot-assisted laparoscopic bladder diverticulectomy (RALBD) with a focus on technical modifications aimed at accommodating for differences in anatomy and pathologies.
A prospective database was maintained for 20 patients who had RALBD at our institution. Clinicopathological and follow-up details including concomitant procedure performed were reviewed for each case. Two patients had intra-diverticular urothelial carcinoma refractory to endoscopic and intravesical management. The dissection of the diverticular neck was performed utilising one of the 3 approaches extravesical (8 of 20 patients), transvesical (11), and trans-diverticular (1). Pre and postoperative postvoid residual and International Prostate Symptom Score were compared using paired-sample t test. learn more In addition, 6 patients underwent open bladder diverticulectomy during the period and their perioperative parameters were compared with the RALBD group.
The median age was 66 and the average BMI was 27.2. Thirteen patients underwent major concomitant urologic procedures. Mean operative duration was 184 minutes with average length of hospital stay at 2.1 days. One Clavien 3 complication was encountered. There were significant improvements in pre & postoperative postvoid residual (425-49 ml, P = .000) and International Prostate Symptom Score (19-6, P = .033). When compared to open bladder diverticulectomy, RALBD is associated with reductions in blood loss (100 ml vs 283 ml, P = 0.003).
Despite the wide variability in clinical presentations, RALBD is associated with minimal surgical morbidity and good perioperative outcomes. It can be safely performed in conjunction with other major urologic procedures in the pelvis.
Despite the wide variability in clinical presentations, RALBD is associated with minimal surgical morbidity and good perioperative outcomes. It can be safely performed in conjunction with other major urologic procedures in the pelvis.
Invasive fungal diseases and especially Cryptococcus neoformans infections are increasingly reported in patients with hematological malignancies receiving ibrutinib, a Bruton's tyrosine kinase inhibitor.
We reported three additional cases and reviewed 16 previous published cases together with cases from the international pharmacovigilance database.
Patients were mainly treated for chronic lymphocytic leukemia. Cryptococcosis mostly occurred during the first six months (66%) and especially the first two months (44%) of treatment. Clinical presentation is often pulmonary (68%) and the outcome is usually favorable despite ibrutinib continuation.
Clinicians must be aware of this infection in patients with hematological malignancies on ibrutinib.
Clinicians must be aware of this infection in patients with hematological malignancies on ibrutinib.Tissue characterization represents a prerogative of cardiac magnetic resonance. Beside late gadolinium enhancement, native T1 mapping (nT1m) reveals tissue composition. It could represent a useful tool for example when contrast medium can't be administrated. The present review summarises current evidence about nT1m in main heart diseases.Numerous studies have investigated grey matter (GM) volume changes in diverse patient groups. Reports of disorder-related GM reductions are common in such work, but many studies also report evidence for GM volume increases in patients. It is unclear whether these GM increases and decreases are independent or related in some way. Here, we address this question using a novel meta-analytic network mapping approach. We used a coordinate-based meta-analysis of 64 voxel-based morphometry studies of psychiatric disorders to calculate the probability of finding a GM increase or decrease in one region given an observed change in the opposite direction in another region. Estimating this co-occurrence probability for every pair of brain regions allowed us to build a network of concurrent GM changes of opposing polarity. Our analysis revealed that disorder-related GM increases and decreases are not independent; instead, a GM change in one area is often statistically related to a change of opposite polarity in other areas, highlighting distributed yet coordinated changes in GM volume as a function of brain pathology. Most regions showing GM changes linked to an opposite change in a distal area were located in salience, executive-control and default mode networks, as well as the thalamus and basal ganglia. Moreover, pairs of regions showing coupled changes of opposite polarity were more likely to belong to different canonical networks than to the same one. Our results suggest that regional GM alterations in psychiatric disorders are often accompanied by opposing changes in distal regions that belong to distinct functional networks.
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