Notes

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mptoms, reduce the incidence of complications, improve the recovery of the IL-6, CRP, and D-dimer levels and enhance patients' sleep quality.
To study the effects of acupuncture on clinical outcomes and helper T cell levels in patients with convalescent ischemic stroke.

One hundred and thirty-six patients with cerebral ischemic stroke were selected for this prospective study. Patients in the control group were treated with routine therapy, and patients in the observation group were treated with acupuncture for 30 minutes once a day for 14 days plus the treatment of the control group. The clinical efficacy, cognitive function, T cell subsets distribution and inflammatory factors of patients in both groups were recorded before and after treatment.

Total effectiveness rate of the observation group was significantly higher than that of the control group (P<0.05). After treatment, CD3
cell percentage, CD4
cell percentage and CD4
cell percentage/CD8
cell percentage of patients in both groups were significantly increased (P<0.05), while CD8
cell percentage in both groups was significantly decreased (P<0.05). Compared to those in the control group, the overall response rate as well as CD3
cell percentage, CD4
cell percentage and CD4
/CD8
of patients after treatment in the observation group were higher (P<0.001), while CD8
cell percentage was lower (all P<0.001). Moreover, the improvement in inflammatory factors as well as scores of Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in observation group were better than those of the control group (P<0.001) respectively.

Treatment of cerebral ischemic stroke by acupuncture can improve clinical outcome and cognitive function, which may be related to its regulation of immune response and reduction of inflammation in vivo.
Treatment of cerebral ischemic stroke by acupuncture can improve clinical outcome and cognitive function, which may be related to its regulation of immune response and reduction of inflammation in vivo.
This study aimed to investigate the effects of high-dose rocuronium bromide in general anesthesia for spinal surgery and analyze its safety.

A total of 90 patients with spine diseases who underwent elective spinal surgery in our hospital were enrolled as study subjects, and were divided into 2-fold group (intraoperative administration of 0.6 mg/kg rocuronium bromide, n=30), 3-fold group (0.9 mg/kg rocuronium bromide, n=30) and 4-fold group (1.2 mg/kg rocuronium bromide, n=30). The effects of rocuronium bromide on muscle relaxation, the operative time and the incidence of adverse reactions were compared among the three groups.

The onset time of muscle relaxation in the 4-fold group was significantly lower than that in 2-fold and 3-fold groups. The duration of muscle relaxation and duration of action in the 4-fold group were significantly higher than those in the 2-fold and 3-fold groups (
<0.05). The satisfaction rate in the 4-fold group (100.00%) was significantly higher than that in the 2-fold grountubation conditions, has longer duration of action, and shortens the patient's operative time, without increasing adverse reactions such as skin flushing, rash, increased airway resistance and bronchospasm, laryngeal edema, etc. Meanwhile, high-dose rocuronium bromide can shorten intubation time, which is conducive to the smooth operation and reduces surgical stress injuries.
To explore the clinical treatment outcomes and parental satisfaction of children with diarrhea receiving comprehensive nursing intervention.

A total of 128 diarrheic children treated in our hospital from June 2016 to June 2017 were recruited and divided into a control group (n=64) receiving conventional nursing and an observation group (n=64) receiving comprehensive nursing intervention, as per a random number table. The clinical outcomes, electrolyte disorders, recovery of gastrointestinal function, quality of life and parental satisfaction were compared between the two groups after nursing.

The overall response rate of the observation group was higher than that of the control group (81.25% vs. 51.56%) (
< 0.05). Nursing satisfaction in the observation group was higher than that in the control group (100.00% vs. 75.00%) (
< 0.05). EGFR inhibitor However, the time to resolution of clinical symptoms and time to return of bowel sounds in the observation group were shorter than those in the control group (
< 0.05). After nursing, the incidence of electrolyte disorders in the observation group was lower than that in the control group. The scores of physical symptoms, physical functioning, emotional functioning, cognitive functioning and social functioning in PedsQLTM Measurement Model were higher than those in the control group, and the electrolyte index monitoring results were better than those in the control group (
< 0.05).

Comprehensive nursing intervention can effectively reduce the incidence of electrolyte disorders, improve parental satisfaction, accelerate the recovery of gastrointestinal function and improve the quality of life in the treatment of pediatric diarrhea.
Comprehensive nursing intervention can effectively reduce the incidence of electrolyte disorders, improve parental satisfaction, accelerate the recovery of gastrointestinal function and improve the quality of life in the treatment of pediatric diarrhea.
We explored and analyzed the effect and masticatory function of ultrasonic subgingival curettage combined with rinsing and gargling of Xipayi gingival rinse on patients with moderate to severe chronic periodontitis.

We selected 98 patients with moderate to severe chronic periodontitis admitted to our hospital, and randomly divided them into observation group and control group (n=49 in each group). The control group was treated with ultrasonic subgingival curettage. The observation group received ultrasonic subgingival curettage with Xipayi gingival rinse, and continued to use-Xipayi gingival rinse for 4 weeks. The changes of periodontal index, inflammatory degree of gingival crevicular fluid, occlusal and masticatory efficiency before and after treatment were compared.

The periodontal indexes and the degree of inflammatory factors in gingival crevicular fluid of the two groups post-treatment decreased critically than those of pre-treatment (
), and the periodontal index and the degree of inflammatory ff clinical application.
The combined therapy of ultrasonic subgingival curettage and Xipayi gingival rinse can effectively cure moderate to severe chronic periodontitis. Through this treatment, patients can improve periodontal condition and inhibit periodontal inflammation. Meanwhile, patients can improve the stability of occlusion and increase the bite force, thus improving the chewing efficiency. Therefore, the application of this method is worthy of clinical application.
To investigate the effect of Shujin Xiaotong capsules combined with ultrashort wave therapy on pain, high-sensitivity C-reactive protein (hs-CRP) level and inflammatory cytokines in patients with chronic knee osteoarthritis.

One hundred and eighteen patients with chronic knee osteoarthritis included in this study were randomly divided into the control group (n=59) and the experimental group (n=59). The patients in the control group were treated with Shujin Xiaotong capsules, and the patients in the experimental group were treated with Shujin Xiaotong capsules combined with ultrashort wave therapy. The knee motion before and after treatment, pain and curative effect were evaluated by the Lysholm Scale, Mc-Gee Scale and Japanese Orthopaedic Association (JOA) Score, respectively. Color Doppler ultrasonography was performed to observe the blood flow in the synovium of knee joint. Serum inflammatory cytokines and oxidative stress indicators were measured using corresponding kits. The quality of life of the pat (all P<0.05).

Shujin Xiaotong capsules combined with physical ultrashort wave therapy can significantly reduce serum inflammation cytokines and hs-CRP expression and pain, as well as improve serum oxidative stress levels, knee joint function and quality of life in patients with chronic knee osteoarthritis.
Shujin Xiaotong capsules combined with physical ultrashort wave therapy can significantly reduce serum inflammation cytokines and hs-CRP expression and pain, as well as improve serum oxidative stress levels, knee joint function and quality of life in patients with chronic knee osteoarthritis.
To explore the influence of minimally invasive surgery (MIS) combined with postoperative intracranial pressure (ICP) monitoring on Glasgow Outcome Scale (GOS) score and postoperative complications of hypertensive intracerebral hemorrhage (HICH).

From January 2018 to January 2020, 106 patients with HICH admitted to Qingdao Municipal Hospital were divided into two groups according to different treatment methods. Among them, 56 cases in the research group received neuroendoscopy minimally invasive surgery (MIS) combined with ICP monitoring, while 50 cases in the control group received only neuroendoscopy MIS. Perioperative indexes, complication rate within 6 months after operation, GOS scores, and GOS grades 6 months after operation, Activities of Daily Living (ADL) scores before and 6 months after operation, and National Institute of Health stroke scale (NIHSS) scores before and 14 days after operation were compared between the two groups, and the quality of life of patients was evaluated in the two groups 6 months after operation.

Compared with the control group, the patients in the research group had notably better indexes of operation time, length of hospital stay, hematoma absorption time, intra-operative blood loss, and hematoma clearance rate, and notably lower incidence of postoperative complications. Moreover, the patients in the research group had markedly higher GOS and ADL scores at 6 months after operation, as well as markedly higher NIHSS score at 14 days after operation.

MIS combined with postoperative ICP monitoring can improve the prognosis of patients with HICH, reduce postoperative complications, and improve postoperative activities and quality of life.
MIS combined with postoperative ICP monitoring can improve the prognosis of patients with HICH, reduce postoperative complications, and improve postoperative activities and quality of life.
To investigate the effect of continuous renal replacement therapy (CRRT) combined with ulinastatin, a broad-spectrum enzyme inhibitor, on the treatment effect and inflammatory mediator levels in patients with severe acute pancreatitis (SAP).

A total of 80 patients with SAP admitted to our hospital were divided into two groups according to a random number table, with 40 cases in the control group and 40 cases in the experimental group. The control group was treated with the broad-spectrum enzyme inhibitor ulinastatin, and the experimental group was treated with continuous renal replacement therapy (CRRT) in addition to the control group's treatment method. The clinical efficacy was evaluated. Serum inflammation indicators, critical illness-related scores, pancreatic microcirculation and coagulation indicators were also detected before and after treatment.

After 14 days of continuous intervention, the total effective rate of the experimental group was 92.50%, and that of the control group was 75.00%, with statistical significance between the two groups (P<0.
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