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Theoretically, the generalization bound of LapWR is derived based on analyzing its Rademacher complexity, which suggests that our proposed algorithm is guaranteed to obtain satisfactory performance. By comparing LapWR with the existing representative SSL algorithms on various benchmark and real-world datasets, we experimentally found that LapWR performs robustly to outliers and is able to consistently achieve the top-level results.OBJECTIVE Birth asphyxia is one of the leading causes of neonatal deaths. A key for survival is performing immediate and continuous quality newborn resuscitation. A dataset of recorded signals during newborn resuscitation, including videos, has been collected in Haydom, Tanzania, and the aim is to analyze the treatment and its effect on the newborn outcome. An important step is to generate timelines of relevant resuscitation activities, including ventilation, stimulation, suction, etc., during the resuscitation episodes. JW74 inhibitor METHODS We propose a two-step deep neural network system, ORAA-net, utilizing low-quality video recordings of resuscitation episodes to do activity recognition during newborn resuscitation. The first step is to detect and track relevant objects using Convolutional Neural Networks (CNN) and post-processing, and the second step is to analyze the proposed activity regions from step 1 to do activity recognition using 3D CNNs. RESULTS The system recognized the activities newborn uncovered, stimulation, ventilation and suction with a mean precision of 77.67 %, a mean recall of 77,64 %, and a mean accuracy of 92.40 %. Moreover, the accuracy of the estimated number of Health Care Providers (HCPs) present during the resuscitation episodes was 68.32 %. CONCLUSION The results indicate that the proposed CNN-based two-step ORAA-net could be used for object detection and activity recognition in noisy low-quality newborn resuscitation videos. SIGNIFICANCE A thorough analysis of the effect the different resuscitation activities have on the newborn outcome could potentially allow us to optimize treatment guidelines, training, debriefing, and local quality improvement in newborn resuscitation.Individuals, such as voice-related professionals, elderly people and smokers, are increasingly suffering from voice disorder, which implies the importance of pathological voice repair. Previous work on pathological voice repair only concerned about sustained vowel /a/, but multiple vowels repair is still challenging due to the unstable extraction of pitch and the unsatisfactory reconstruction of formant. In this paper, a multiple vowels repair based on pitch extraction and Line Spectrum Pair feature for voice disorder is proposed, which broadened the research subjects of voice repair from only single vowel /a/ to multiple vowels /a/, /i/ and /u/ and achieved the repair of these vowels successfully. Considering deep neural network as a classifier, a voice recognition is performed to classify the normal and pathological voices. Wavelet Transform and Hilbert-Huang Transform are applied for pitch extraction. Based on Line Spectrum Pair (LSP) feature, the formant is reconstructed. The final repaired voice is obtained by synthesizing the pitch and the formant. The proposed method is validated on Saarbrücken Voice Database (SVD) database. The achieved improvements of three metrics, Segmental Signal-to-Noise Ratio, LSP distance measure and Mel cepstral distance measure, are respectively 45.87%, 50.37% and 15.56%. Besides, an intuitive analysis based on spectrogram has been done and a prominent repair effect has been achieved.Sleep staging is to score the sleep state of a subject into different sleep stages such as Wake and Rapid Eye Movement (REM). It plays an indispensable role in the diagnosis and treatment of sleep diseases. As manual sleep staging through well-trained sleep experts is time consuming, tedious, and subjective, many automatic methods have been developed for accurate, efficient, and objective sleep staging. Recently, deep learning based methods have been successfully proposed for EEG based sleep staging with promising results. However, most of these methods directly take EEG raw signals as input of convolutional neural networks (CNNs) without considering the domain knowledge of EEG staging. Apart from that, to capture temporal information, most of the existing methods utilize recurrent neural networks such as LSTM (Long Short Term Memory) which are not effective for modelling global temporal context and difficult to train. Therefore, inspired by the clinical guidelines of sleep staging such as AASM (American Academy of Sleep Medicine) rules where different stages are generally characterized by EEG waveforms of various frequencies, we propose a multi-scale deep architecture by decomposing an EEG signal into different frequency bands as input to CNNs. To model global temporal context, we utilize the multi-head self-attention module of the transformer model to not only improve performance, but also shorten the training time. In addition, we choose residual based architecture which makes training end-to-end. Experimental results on two widely used sleep staging datasets, Montreal Archive of Sleep Studies (MASS) and sleep-EDF datasets, demonstrate the effectiveness and significant efficiency (up to 12 times less training time) of our proposed method over the state-of-the-art.Atypical Hepatocellular Carcinoma (HCC) is very hard to distinguish from Focal Nodular Hyperplasia (FNH) in routine imaging. However little attention was paid to this problem. This paper proposes a novel liver tumor Computer-Aided Diagnostic (CAD) approach extracting spatio-temporal semantics for atypical HCC. With respect to useful diagnostic semantics, our model automatically calculates three types of semantic feature with equally down-sampled frames based on Contrast-Enhanced Ultrasound (CEUS). Thereafter, a Support Vector Machine (SVM) classifier is trained to make the final diagnosis. Compared with traditional methods for diagnosing HCC, the proposed model has the advantage of less computational complexity and being able to handle the atypical HCC cases. The experimental results show that our method obtained a pretty considerable performance and outperformed two traditional methods. According to the results, the average accuracy reaches 94.40%, recall rate 94.76%, F1-score value 94.62%, specificity 93.62% and sensitivity 94.
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