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The theme re-adjustment with life was identified for postrecovery from COVID-19.
COVID-19-positive individuals have myriad of experiences from their transition of being positive to finally being free of infection. Their experience with the illness sheds light on the gray areas like stigma that demand immediate attention. Future policies need to be developed in accordance with the identified perceived needs to potentially guide the satisfaction and recovery of COVID-19-positive individuals.
COVID-19-positive individuals have myriad of experiences from their transition of being positive to finally being free of infection. Their experience with the illness sheds light on the gray areas like stigma that demand immediate attention. Future policies need to be developed in accordance with the identified perceived needs to potentially guide the satisfaction and recovery of COVID-19-positive individuals.
Postoperative delirium significantly delays the recovery of patients. This study sought to explore the risk factors and to prevent postoperative delirium after orthopedic surgery.
In the part of retrospective study, 456 cases over 70-year-old that underwent one of three types of orthopedic surgery were included and were defined as the retrospective group. The risk factors of postoperative delirium were analyzed by logistic regression. In the part of prospective study, 86 cases of the same age and the same surgery were included and were defined as the prospective group. Positive interventions were used by shortening the fasting time and increasing the perioperative rehydration. The differences of postoperative delirium incidence between the retrospective group and the prospective group were analyzed.
Compared with patients with normal postoperative electrolytes, postoperative creatinine <68.20 μmol/L, and fluid infusion during fasting >119.66 mL/h, postoperative electrolyte disorders (odds ratio [O could be reduced.
Major depressive disorder (MDD) is a common psychiatric disorder characterized by constant sadness and a lack of interest in work and social interactions. Maintaining the transcriptome levels via the controlled regulation of mRNA processing and transport is essential to alleviating MDD. Various molecular phenotypes such as aberrant RNA splicing and stability are identified as critical determinants of MDD.
This study aims to compare the mRNA expression profiles between major depressive disorder non-suicide (MDD), major depressive disorder suicide (MDD-S), and control groups using RNA-Seq.
A transcriptomics and sequencing analysis of gene expression profiling was conducted in 9 patients with MDD, 10 patients with MDD-S, and 10 control patients.
A comparison of the sample groups revealed that the PRKACB gene was upregulated in patients with MDD. read more At the same time, GRM3, DLGAP1, and GRIA2 were downregulated in these patients-these genes are majorly involved in the glutamatergic pathway. Five genes (GRIA1, CAMK2D, PPP3CA, MAPK10, and PPP2R2A) of the dopaminergic pathway were downregulated in patients with the MDD-S condition when compared with the MDD and control groups. Cholinergic synapses were altered in patients with MDD when compared to the control group due to the presence of dysregulated genes (KCNQ5, PLCB4, ADCY9, CAMK2D, PIK3CA, and GNG2).
The results provide a new understanding of the etiology of depression in humans and identify probable depression-associated biomarkers.
The results provide a new understanding of the etiology of depression in humans and identify probable depression-associated biomarkers.
Yoga has been extensively used as an alternative or complementary therapy in psychiatric disorders depending on the type and severity of the disorders. However, data related to perspective on yoga services and the benefits and adverse effects attributed to yoga by patients with major psychiatric disorders is lacking.
The aim of the study was to assess feedback of the patients who attended yoga sessions at a Yoga center in a tertiary neuropsychiatric hospital.
This was a cross-sectional retrospective study using a specific questionnaire to get feedback from patients referred to the NIMHANS Integrated Center for Yoga, at the end of their yoga training.
Two hundred and one patients' data were included in this retrospective study. Most of the patients were referred by the doctors. The yoga module for schizophrenia was most commonly utilized, followed by depression. On an average, patients attended 13 sessions. Most of them practiced yoga for 1-2 weeks and had missed less than 2 sessions. The great majoritffects.
The impact of the coronavirus disease 2019 (COVID-19) pandemic on mental disorders in postnatal period remains unknown.
The study aimed to determine the extent to which the COVID-19 pandemic may aggravate depressive symptoms and psychological distress of women with high-risk pregnancy in postnatal period.
This prospective cross-sectional study was conducted on women with complicated pregnancies from antenatal to postnatal period. In the first phase, from December 2019 to January 2020 (before the beginning of the COVID-19 pandemic), 122 pregnant women filled in the Edinburgh Postnatal Depression Scale (EPDS) and Brief Symptom Inventory 53-items (BSI-53). In the second phase, with the start of the COVID-19 pandemic from February to June, 30% of the participants (41/122) completed three questionnaires EPDS, BSI-53, and the posttraumatic stress disorder (PTSD) scale in postpartum period.
During the COVID-19 pandemic, from antenatal to postnatal period, the depression score of EPDS, total scores, all the subscales of BSI-53, and global severity index-53 increased in women with high-risk pregnancy. Furthermore, the persistence of antenatal depression occurred in 85.7% of the participants, and the onset of postnatal depression occurred in 80% of them. About 12% of the women also experienced PTSD symptoms during the postnatal period.
The COVID-19 pandemic may aggravate the prevalence and persistence of postnatal depression in women with high-risk pregnancy. The study calls for clinical implementation to identify and help women with mental disorders in postnatal period, especially women experiencing complicated pregnancies.
The COVID-19 pandemic may aggravate the prevalence and persistence of postnatal depression in women with high-risk pregnancy. The study calls for clinical implementation to identify and help women with mental disorders in postnatal period, especially women experiencing complicated pregnancies.This systematic review and meta-analysis aimed to provide a summary of the existing evidence on the prevalence of depression among cancer patients worldwide to assist health policymakers in adopting appropriate measures to prevent and control depression in these patients. EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were searched for original studies published in English from January 2000 to July 2019. The studies were screened on the basis of quality and relevance criteria. The statistical analyses were conducted in the R software. Out of 182,521 cancer patients examined in 183 studies, 49,280 (~27%) had depression (95% confidence interval [CI] = 24%-30%). The highest prevalence of depression was among patients with colorectal cancer with 32% (95% CI = 20%-47%). Among countries, Pakistan with 43% (95% CI = 26%-64%), and among continents, Africa with 36% (95% CI = 29%-43%) had the highest prevalence of reported depression in cancer patients. Adjusting for sample size, the prevalence of depression among female cancer patients, 31% (95% CI = 26%-36%), was higher than men, 26% (95% CI = 21%-31%). The prevalence of depression among cancer patients is increasing by an average of 0.6% per year. The findings show higher prevalence of depression among cancer patients in underdeveloped and developing countries compared to the developed nations and the global average.The five largest planets all have strong intrinsic magnetic fields that interact with their satellites, many of which contain electrically conducting materials on global scales. Conducting bodies exposed to time-varying magnetic fields induce secondary magnetic fields from movement of eddy currents. In the case of spherically symmetric conducting bodies, matching magnetic solutions at the boundary results in relatively simple relations between the excitation field and the induced field. In this work, we determine the more complicated induced magnetic field from a near-spherical conductor, where the outer boundary is expanded in spherical harmonics. Under the approximations that the excitation field is uniform at a single frequency, the product of wavenumber and radius for the body is large, and the average radius of the body is large compared to the perturbation from spherical symmetry, we find that each spherical harmonic in the shape expansion induces discrete magnetic moments that are independent from the other harmonics in the expansion. That is, simple superposition applies to the magnetic moments induced by each perturbation harmonic. We present a table of the magnetic moments induced by each spherical harmonic up to degree 2 in the perturbed shape. We also present a simple formula by which the induced magnetic field may be evaluated for any arbitrary shape described by expanding the radius of the conducting body in spherical harmonics. Unlike the Earth, many moons in the Solar System are tidally locked to their parent bodies, and many also contain saline, subsurface oceans. Conductive material in these moons is therefore expected to be non-spherical. Accounting for the boundary shape of Europa's ocean will be critical for interpretation of Europa Clipper magnetic measurements near the moon, where the effects of quadrupole-and-higher magnetic moments will be most apparent. The results of this work permit magnetic studies considering non-spherical oceans of satellites for the first time.Humanitarian events are increasing globally, both in number and intensity. In response, the international community spends approximately US$30 billion annually to alleviate both the immediate consequences of these climatic, geographic, and human-induced events but also to support mitigation and recovery. Over the past two decades, the humanitarian sector has increasingly professionalised. One under-studied aspect of this professionalisation is an increase in postgraduate studies in humanitarian action over the last 20 years. Despite this increase, there is no agreement on core curriculum or pedagogy across humanitarian studies courses. How do current Masters of Humanitarian Assistance (MHA) offerings converge and differ, and how can such courses further their contribution to the humanitarian endeavour? This paper surveys 26 anglophone courses offered in the United States, Europe, the United Kingdom, Australia, India, and Nigeria, exploring key characteristics of course entry requirements, flexibility, research, practical components, and academic foci. It does not recommend what a core curriculum for humanitarian courses should be, but does argue that core curriculum for humanitarian courses should be identified by relevant and diverse stakeholders such as affected communities, humanitarian agencies, disaster management bodies, and governments, to ensure that courses in this field provide appropriate learning outcomes. The paper suggests how such a 'charter' may be developed.
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