Notes

Estimated Localized White-colored Matter Hyperintensity Load, Regenerating Express Well-designed Connectivity, and also Cognitive Capabilities inside Seniors.
Due to the sparse rewards and high degree of environmental variation, reinforcement learning approaches, such as deep deterministic policy gradient (DDPG), are plagued by issues of high variance when applied in complex real-world environments. We present a new framework for overcoming these issues by incorporating a stochastic switch, allowing an agent to choose between high- and low-variance policies. The stochastic switch can be jointly trained with the original DDPG in the same framework. In this article, we demonstrate the power of the framework in a navigation task, where the robot can dynamically choose to learn through exploration or to use the output of a heuristic controller as guidance. Instead of starting from completely random actions, the navigation capability of a robot can be quickly bootstrapped by several simple independent controllers. The experimental results show that with the aid of stochastic guidance, we are able to effectively and efficiently train DDPG navigation policies and achieve significantly better performance than state-of-the-art baseline models.This article solves the exponential synchronization issue of memristor-based complex-valued neural networks (MCVNNs) with time-varying uncertainties via feedback control. Compared with the traditional control methods, a more practical and general control scheme with the available uncertain information of the parameters is newly developed for MCVNNs. Our approach considers the proposed neural networks as two dynamic real-valued systems. Then, the less conservative exponential synchronization criteria are proposed by incorporating the framework of the Lyapunov method and inequality techniques. Under the proposed algorithm, not only can the stability of MCVNNs be guaranteed but also the behavior of such a system is appropriate for image protection. Meanwhile, the sensitive measure of the encryption and decryption can be converted into synchronization error. When monitoring the secure mechanism as a whole, the influence of error feasible domain on image decryption is analyzed. Simulation examples are provided to verify the efficacy of the proposed synchronization criterion and the results of practical application on image protection.Several previous works have studied the application of proxy-based rendering algorithms to underactuated haptic devices. However, all these works make oversimplifying assumptions about the configuration of the haptic device, and they ignore the user's intent. In this work, we lift those assumptions, and we carry out a theoretical study that unveils the existence of unnatural ghost forces under typical proxy-based rendering. We characterize and quantify those ghost forces. In addition, we design a novel rendering strategy, with anisotropic coupling between the device and the proxy. With this strategy, the forces rendered by an underactuated device are a best match of the forces rendered by a fully actuated device. We have demonstrated our findings on synthetic experiments and a simple real-world experiment.The recovery of sparse signals given their linear mapping on lower-dimensional spaces can be partitioned into a support estimation phase and a coefficient estimation phase. We propose to estimate the support with an oracle based on a deep neural network trained jointly with the linear mapping at the encoder. The divination of the oracle is then used to estimate the coefficients by pseudo-inversion. This architecture allows the definition of an encoding-decoding scheme with state-of-the-art recovery capabilities when applied to biological signals such as ECG and EEG, thus allowing extremely low-complex encoders. As an additional feature, oracle-based recovery is able to self-assess, by indicating with remarkable accuracy chunks of signals that may have been reconstructed with a non-satisfactory quality. This self-assessment capability is unique in the CS literature and paves the way for further improvements depending on the requirements of the specific application. As an example, our scheme is able to satisfyingly compress by a factor of 2.67 an ECG or EEG signal with a complexity equivalent to only 24 signed sums per processed sample.The recent advances in wet-lab automation enable high-throughput experiments to be conducted seamlessly. In particular, the exhaustive enumeration of all possible conditions is always involved in high-throughput screening. Nonetheless, such a screening strategy is hardly believed to be optimal and cost-effective. By incorporating artificial intelligence, we design an open-source model based on categorical matrix completion and active machine learning to guide high throughput screening experiments. Specifically, we narrow our scope to the high-throughput screening for chemical compound effects on diverse protein sub-cellular locations. In the proposed model, we believe that exploration is more important than the exploitation in the long-run of high-throughput screening experiment, Therefore, we design several innovations to circumvent the existing limitations. In particular, categorical matrix completion is designed to accurately impute the missing experiments while margin sampling is also implemented for uncertainty estimation. The model is systematically tested on both simulated and real data. The simulation results reflect that our model can be robust to diverse scenarios, while the real data results demonstrate the wet-lab applicability of our model for high-throughput screening experiments. Lastly, we attribute the model success to its exploration ability by revealing the related matrix ranks and distinct experiment coverage comparisons.Utilizing cell culture medium to grow cells in vitro has been widely studied in the past decades and has been recognized as an acknowledged way for investigating cell activities. However, due to the lack of adequate observation tools, the detailed mechanisms regulating cell growth in cell culture medium are still not fully understood. Glutathione purchase In this work, atomic force microscopy (AFM), a powerful tool for observing native biological systems under near-physiological conditions with high resolution, was applied to reveal the nanogranular surfaces formed in cell culture medium in situ for promoting cell growth. First, AFM imaging of glass slides (glass slides were previously incubated in cell culture medium) in aqueous environment clearly visualized the cell culture medium-forming nanogranular surfaces on glass slides. By altering the incubation time of glass slides in cell culture medium, the dynamic formation of nanogranular surfaces was remarkably observed. Next, fluorescent labeling experiments of the cell culture medium-treated glass slides showed that bovine serum proteins were contained in the nanogranular surfaces. Further, the adhesive interactions between cells and nanogranular surfaces probed by AFM force spectroscopy and the cell growth experiments showed that cell culture medium-forming nanogranular surfaces promote cell attachment and growth. The study provides novel insights into nanotopography-regulated molecular mechanisms in cell growth and demonstrates the outstanding capabilities of AFM in addressing biological issues with unprecedented spatial resolution under aqueous conditions, which will have potential impacts on the studies of cell behaviors and cell functions.We evaluated different muscle excitation estimation techniques, and their sensitivity to Motor Unit (MU) distribution in muscle tissue. For this purpose, the Convolution Kernel Compensation (CKC) method was used to identify the MU spike trains from High-Density ElectroMyoGrams (HDEMG). Afterwards, Cumulative MU Spike Train (CST) was calculated by summing up the identified MU spike trains. Muscle excitation estimation from CST was compared to the recently introduced Cumulative Motor Unit Activity Index (CAI) and classically used Root-Mean-Square (RMS) amplitude envelop of EMG. To emphasize their dependence on the MU distribution further, all three muscle excitation estimates were used to calculate the agonist-antagonist co-activation index. We showed on synthetic HDEMG that RMS envelopes are the most sensitive to MU distribution (10 % dispersion around the real value), followed by the CST (7 % dispersion) and CAI (5 % dispersion). In experimental HDEMG from wrist extensors and flexors of post-stroke subjects, RMS envelopes yielded significantly smaller excitations of antagonistic muscles than CST and CAI. As a result, RMS-based co-activation estimates differed significantly from the ones produced by CST and CAI, illuminating the problem of large diversity of muscle excitation estimates when multiple muscles are studied in pathological conditions. Similar results were also observed in experimental HDEMG of six intact young males.Efficient and accurate segmentation of full 4D light fields is an important task in computer vision and computer graphics. The massive volume and the redundancy of light fields make it an open challenge. In this paper, we propose a novel light field hypergraph (LFHG) representation using the light field super-pixel (LFSP) for interactive light field segmentation. The LFSPs not only maintain the light field spatio-angular consistency, but also greatly contribute to the hypergraph coarsening. These advantages make LFSPs useful to improve segmentation performance. Based on the LFHG representation, we present an efficient light field segmentation algorithm via graph-cut optimization. Experimental results on both synthetic and real scene data demonstrate that our method outperforms state-of-the-art methods on the light field segmentation task with respect to both accuracy and efficiency.Mesh color edit propagation aims to propagate the color from a few color strokes to the whole mesh, which is useful for mesh colorization, color enhancement and color editing, etc. Compared with image edit propagation, luminance information is not available for 3D mesh data, so the color edit propagation is more difficult on 3D meshes than images, with far less research carried out. This paper proposes a novel solution based on sparse graph regularization. Firstly, a few color strokes are interactively drawn by the user, and then the color will be propagated to the whole mesh by minimizing a sparse graph regularized nonlinear energy function. The proposed method effectively measures geometric similarity over shapes by using a set of complementary multiscale feature descriptors, and effectively controls color bleeding via a sparse ℓ1 optimization rather than quadratic minimization used in existing work. The proposed framework can be applied for the task of interactive mesh colorization, mesh color enhancement and mesh color editing. Extensive qualitative and quantitative experiments show that the proposed method outperforms the state-of-the-art methods.Recent works on adaptive sparse and on low-rank signal modeling have demonstrated their usefulness in various image/video processing applications. Patch-based methods exploit local patch sparsity, whereas other works apply low-rankness of grouped patches to exploit image non-local structures. However, using either approach alone usually limits performance in image reconstruction or recovery applications. In this work, we propose a simultaneous sparsity and low-rank model, dubbed STROLLR, to better represent natural images. In order to fully utilize both the local and non-local image properties, we develop an image restoration framework using a transform learning scheme with joint low-rank regularization. The approach owes some of its computational efficiency and good performance to the use of transform learning for adaptive sparse representation rather than the popular synthesis dictionary learning algorithms, which involve approximation of NP-hard sparse coding and expensive learning steps. We demonstrate the proposed framework in various applications to image denoising, inpainting, and compressed sensing based magnetic resonance imaging.
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