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Crochetage signal might forecast past due atrial arrhythmias within patients with secundum atrial septal defect going through transcatheter closing.
These revelations signify the importance of ZEONEX-based POFBGs, which allow consistent and effective grating fabrication and are highly promising in the foreseeable future for biomedical applications.In the quest for a more compact and cheaper Raman sensor, photonic integration and plasmonic enhancement are central. Nanoplasmonic slot waveguides exhibit the benefits of SERS substrates while being compatible with photonic integration and mass-scale (CMOS) fabrication. A difficulty in pursuing further integration of the Raman sensor with lasers, spectral filters, spectrometers and interconnecting waveguides lies in the presence of a photon background generated by the excitation laser field in any dielectric waveguide constituting those elements. Here, we show this problem can be mitigated by using a multi-mode interferometer and a nanoplasmonic slot waveguide operated in back-reflection to greatly suppress the excitation field behind the sensor while inducing very little photon background.The performance of high-operating-temperature (HOT) longwavelength infrared (LWIR) HgCdTe avalanche photodiodes (APDs) is significantly limited by the increasing dark current related to temperature. In this paper, a novel barrier-blocking LWIR pBp-APD structure is proposed and studied, and the results show that the dark current of pBp-APD is significantly restricted compared with conventional APD without sacrificing the gain at high temperature. Furthermore, the reduction of avalanche dark current is found to be the key points of the significant suppression of dark current. find more The physical essence of this reduction is revealed to be the depletion of carriers in the absorption region, and the feasibility of the improved structure is further confirmed by the analysis of its energy band and electric field distribution. In addition, the reduction of gain-normalized dark current (GNDC) does not need to sacrifice the gain. The proposed LWIR pBp-APD paves the way for development of high operation temperature infrared APDs.The parallel Monte Carlo software CUDAMCML used in the bio-optics field was developed by Erik Alerstam et al. (J. Biomed. Opt., 13, 060504, 2008) based on the Compute Unified Device Architecture (CUDA) and can simulate light transport in multilayered media. In the present study, CUDAMCML is extended to form the new program CUDAMCML-OCEAN using the average sampling method. This new program can handle multiple types of particle seawater containing elements such as colored dissolved organic matter (CDOM) and bubbles. The accuracy and speedup of the new program are analyzed. The results show that when the parameters are set appropriately, the speedup of CUDAMCML-OCEAN is more than 200 times compared with serial code. And the accuracies of the spectral reflectance and transmittance all reached a satisfactory level for different wind speeds and chlorophyll concentrations.The plasmon resonance of a structure is primarily dictated by its optical properties and geometry, which can be modified to enable hot-carrier photodetectors with superior performance. Recently, metal alloys have played a prominent role in tuning the resonance of plasmonic structures through chemical composition engineering. However, it has been unclear how alloying modifies the time dynamics of the generated hot-carriers. In this work, we elucidate the role of chemical composition on the relaxation time of hot-carriers for the archetypal AuxAg1-x thin film system. Through time-resolved optical spectroscopy measurements in the visible wavelength range, we measure composition-dependent relaxation times that vary up to 8× for constant pump fluency. Surprisingly, we find that the addition of 2% of Ag into Au films can increase the hot-carrier lifetime by approximately 35% under fixed fluence, as a result of a decrease in optical loss. Further, the relaxation time is found to be inversely proportional to the imaginary part of the permittivity. Our results indicate that alloying is a promising approach to effectively control hot-carrier relaxation time in metals.Surface plasmon polariton (SPP) provides an important platform for the design of various nanophotonic devices. However, it is still a big challenge to achieve spatiotemporal manipulation of SPP under both spatially nanoscale and temporally ultrafast conditions. Here, we propose a method of spatiotemporal manipulation of SPP pulse in a plasmonic focusing structure illuminated by a dispersed femtosecond light. Based on dispersion effect of SPP pulse, we achieve the functions of dynamically controlled wavefront rotation in SPP focusing and redirection in SPP propagation within femtosecond range. The influences of structural parameters on the spatiotemporal properties of SPP pulse are numerically studied, and an analytical model is built to explain the results. The spatiotemporal coupling of modulated SPP pulses to dielectric waveguides is also investigated, demonstrating an ultrafast turning of propagation direction. This work has great potential in applications such as on-chip ultrafast photonic information processing, ultrafast beam shaping and attosecond pulse generation.Rapid cell identification is achieved in a compact and field-portable system employing single random phase encoding to record opto-biological signatures of living biological cells of interest. The lensless, 3D-printed system uses a diffuser to encode the complex amplitude of the sample, then the encoded signal is recorded by a CMOS image sensor for classification. Removal of lenses in this 3D sensing system removes restrictions on the field of view, numerical aperture, and depth of field normally imposed by objective lenses in comparable microscopy systems to enable robust 3D capture of biological volumes. Opto-biological signatures for two classes of animal red blood cells, situated in a microfluidic device, are captured then input into a convolutional neural network for classification, wherein the AlexNet architecture, pretrained on the ImageNet database is used as the deep learning model. Video data was recorded of the opto-biological signatures for multiple samples, then each frame was treated as an input image to the network. The pre-trained network was fine-tuned and evaluated using a dataset of over 36,000 images. The results show improved performance in comparison to a previously studied Random Forest classification model using extracted statistical features from the opto-biological signatures. The system is further compared to and outperforms a similar shearing-based 3D digital holographic microscopy system for cell classification. In addition to improvements in classification performance, the use of convolutional neural networks in this work is further demonstrated to provide improved performance in the presence of noise. Red blood cell identification as presented here, may serve as a key step toward lensless pseudorandom phase encoding applications in rapid disease screening. To the best of our knowledge this is the first report of lensless cell identification in single random phase encoding using convolutional neural networks.We have investigated the effect of cascaded optical nonlinearity on the spatial beam properties of a femtosecond optical parametric oscillator (OPO). The OPO was operated with a tunable phase mismatch by varying the angle of the nonlinear crystal. The cascaded nonlinearity induced self-focusing and defocusing changed resonator's stability and impacted mode properties. With tuning of a phase mismatch, the calculated parabolic part of cascaded nonlinearity lens focal length changes from f ∼ 30 mm (D ∼ 33 m-1 at Δθ ∼ -0.5o) to infinity and back to f ∼ -110 mm (D ∼ -9 m-1 at Δθ ∼ 0.9o) in the LBO nonlinear crystal. Such high power nonlinear lenses in a cavity operated near its stability limit promoted the generation of axially asymmetric or pass-to-pass unstable resonator modes. It was shown that phase mismatched optical parametric oscillation changes the physical character of the resonator from linear to ring-like with two nonlinear crystals having two different focusing powers. Calculations showed that the QCN induced spatial nonlinear phase should lead to severe longitudinal chromatic aberrations for broad spectrum pulses. A numerical simulation in XYZ spatial domain and calculations using ABCD matrix approach confirmed the physical mechanisms underlying the experimental results and allowed for the interpretation of the observed effects.Quantum optical methods have great potential for highly efficient discrimination of chiral molecules. We propose quantum interference-based schemes of enantio-discrimination under microwave regime among molecular rotational states. The quantum interference between field-driven one- and two-photon transitions of two higher states is designed to be constructive for one enantiomer but destructive for the other, since a certain transition dipole moment can be set to change sign with enantiomers. Therefore, two enantiomers can evolve into entirely different states from the same ground state. Through strengthening the constructive interference, the quantum Zeno effect is found in one enantiomer and then its excitation is suppressed, which also enables the enantio-discrimination. We simulate the schemes for differentiating between S and R enantiomers of 1, 2-propanediol (C3H8O2) molecules. With the analysis of the phase sensitivity to microwave fields and the effect of energy relaxations, the highly efficient enantio-discrimination of the 1, 2-propanediol molecules may be achieved.In this paper we present numerical and experimental results revealing that the mode instability threshold of highly Yb-doped, Ce/Al co-doped pedestal fibers is affected by the size of the index-increased pedestal structure surrounding the core. An alternative preparation technology for the realization of large mode area fibers with very large Al-doped silica pedestals is introduced. Three different pedestal fiber design iterations characterized by low photodarkening were manufactured and tested in counter-pumped amplifier setups. Up to 1.9 kW continuous-wave output power of near-diffraction-limited beam quality (M2 = 1.26) was achieved with an 18/200/420 µm fiber of very low NA = 0.042, limited only by the occurrence of mode instabilities.Three and four electromagnetically induced transparency windows generate the multi-channel four-wave mixing (FWM) process are observed in a four-level atomic system. The transmission of the probe field and the reflection of the FWM are investigated in the modulated moving photonic band gap structures which are caused by the coupling fields with a relative small detuning offset when scanning detuning frequency of the probe field and the dressing field, respectively. The experimental results show that the more channels spectrum signal of the FWM process can be modulated and the generated multi-channel can be further modulated by adding a dressing field. We have also explained theoretically these experimental results which may have applications in the design of photonic crystal and optical signal amplifiers.Understanding signal fading effect is essential for the application of Rayleigh-scattering-based distributed acoustic fibre sensors (DASs) due to the nature of coherent beam interference within the pulse length. Statistical properties for the intensity of the Rayleigh backscattered light (i.e. intensity fading) and its impact on the sensitivity of DAS systems have been intensely studied over the last decades. Here we for the first time establish an analytical model for the phase signal retrieved from the dual-pulse heterodyne demodulated DAS system, which can be exploited to investigate the phase fading effect in this system. The developed model reveals that the phase fading phenomenon mainly originates from the randomness in the phase retardant of the Rayleigh scatters. The quantitatively resolved statistical features of the phase fading is confirmed by experimental results. Based on the analytical model, a noise figure is defined to characterize the global fading-induced noise level via taking into account contributions from all channels along the sensing fiber.
Homepage: https://www.selleckchem.com/products/cct241533-hydrochloride.html
     
 
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