Notes

Is fetuin-A the biomarker of dialysis gain access to malfunction?
The surface treatments at baseline led to statistically similar fatigue failure loads (953N-1313N), except for GLZ (1313N), which was significantly higher than 7%Si (953 N). Meanwhile, Ctrl had 40% pre-test failures (debonding) after aging, and therefore the worst fatigue performance (notable decrease in fatigue results), while all the other groups presented superior and statistically similar fatigue behavior (973-1271N). In fact, when considering baseline Vs aging conditions, stable fatigue results could only be noted when using surface treatments. In conclusion, internal surface treatments of FSZ ceramic restorations are mandatory for fatigue behavior stability after aging the restorative set, while non-treatment induced unstable results.In order to adapt to the environment, plants have evolved many structural designs to improve material utilization. The head infructescence can be described as the Fibonacci sequence, in consistent with plant developmental biology. The lignified framework inside the head infructescence possesses idiographic structural designs that optimize maximum energy efficiency, growing space, seed spreading probability, and enhance the mechanical behavior of the infructescences. In this study, the hierarchical structure and mechanical properties of the infructescence of Liquidambar formosana, commonly called Formosan gum, were investigated. Liquidambar formosana has maple-like leaves and burr-like infructescences. The buckyball-like framework inside infructescence consists of chambers (cells), which support the whole structure under compression. Inspired by the framework, we proposed three models Thomson model based on the lowest potential energy state, Poisson disc model indicated random distribution, and spherical Fibonacci model represented plant development. Three-dimensional physical entities of these models were fabricated by additive manufacturing. We discovered that under compression testing, these models appear different mechanical properties and deformation mechanisms based on their structures. Spherical Fibonacci model provides superior mechanical properties compared to Thomson and Poisson disc models due to its unique structural design. It is the first time that spherical Fibonacci model brought into the bio-inspired mechanics models through structural analysis and finite element method. The unique construction of Liquidambar formosana has great potential in the designs of novel lightweight, anti-buckling composites, and bio-inspired architectures.Three-dimensional (3D) printing is an efficient technique for the fabrication of electronic devices. It also enables the use conductive of biomaterials in various applications, such as implants and flexible devices. Designing a new bioink is extremely challenging. For bioelectronics devices, bioink materials should be printable, flexible, conductive, harmless to cells, and sufficiently strong to maintain their shape when immersed in nutrients or under pressure. Over the past few years, several flexible conductive bioinks have been developed that are based on composite pastes containing a biopolymer and conductive micro- and nanoscale materials in the form of metallic particles, conducting polymers, or a mixture of them. Herein, we report a new strategy for the fabrication of a bioink for a commercial 3D printer with the desired conductivity, mechanical properties, and biocompatibility, using a poly(glycerol-co-sebacate) (PGS)-based polymer and zinc. The PGS-based polymer and lithium phenyl-2,4,6-trimethylbenzoylphosphinate (as a photoinitiator) were added to the zinc, and then, the prepared bioink was polymerized during 3D printing under visible light. According to a microstructural investigation using scanning electron microscopy, the zinc particles were homogeneously distributed in the PGSA matrix. The conductivity of bioink increases with chemical sintering and with an increase in the amount of zinc particles. Based on rheology tests, the appropriate printable composition is 60% zinc and 40% PGS-based polymer. This bioink exhibited remarkable mechanical and adhesive properties in comparison with the PGS-based polymer without zinc, according to tensile, compression, lap shear, wound closure, and burst pressure modules. In vitro and in vivo results indicated that the bioink was not toxic to the cells or the animal over a period of culturing.
Although total knee arthroplasty is a well-practiced surgical procedure, material properties and surface topography can contribute to the wear mechanisms and the implant failure. It has been advised that an increased femoral component's surface roughness of total knee prostheses may be a contributing factor to accelerated wear of the polyethylene menisci and eventually prosthesis failure. E3 ligase Ligand chemical The aim of this study is to investigate the wear phenomena occurring on medial and lateral compartments of retrieved total knee arthroplasty in order to correlate the surface roughness vs. BMI, age at revision, and time in situ.

Qualitative visual analyses were performed on all the retrieved knee components to assess the damage due to the wear phenomena. Quantitative analysis includes surface characterization performed using optical apparatus to describe surface roughness and morphology on the retrieved femoral, tibial and polyethylene component. The Mann-Whitney statistical test was performed to correlate the medial vs.onents are subjected and no statistical significance was found between surface roughness measurements and patient BMI, age at revision, and time in situ.
The visual and topographical analysis showed consistent damage patterns with respect to the main movements to which the prosthetic components are subjected and no statistical significance was found between surface roughness measurements and patient BMI, age at revision, and time in situ.
One of the major causes of pelvic organ prolapse is pelvic muscle injury sustained during a vaginal delivery. The most common site of this injury is where the pubovisceral muscle takes origin from the pubic bone. We hypothesized that it is possible for low-cycle material fatigue to occur at the origin of the pubovisceral muscle under the large repetitive loads associated with pushing during the second stage of a difficult labor.

The main goal was to test if the origin of the pubovisceral muscle accumulates material damage under sub-maximal cyclic tensile loading and identify any microscopic evidence of such damage.

Twenty origins of the ishiococcygeous muscle (homologous to the pubovisceral muscle in women) were dissected from female sheep pelvises. Four specimens were stretched to failure to characterize the failure properties of the specimens. Thirteen specimens were then subjected to relaxation and subsequent fatigue tests, while three specimens remained as untested controls. Histology was performed to check for microscopic damage accumulation.
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