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Moreover, an iteration optimizing algorithm is provided to reduce the convergence domain around the sliding surface via searching a desirable sliding gain, which constitutes an effective GA-based sliding-mode control strategy. Finally, the proposed control scheme is verified via the simulation results.This article investigates the model-free containment control of multiple underactuated unmanned surface vessels (USVs) subject to unknown kinetic models. A novel cooperative control architecture is presented for achieving a containment formation under switching topologies. Specifically, a path-guided distributed containment motion generator (CMG) is first proposed for generating reference points according to the underlying switching topologies. Next, guiding-vector-field-based guidance laws are designed such that each USV can track its reference point, enabling smooth transitions during topology switching. Finally, data-driven neural predictors by utilizing real-time and historical data are developed for estimating total uncertainties and unknown input gains, simultaneously. Based on the learned knowledge from neural predictors, adaptive kinetic control laws are designed and no prior information on kinetic model parameters is required. By using the proposed method, the fleet is able to converge to the convex hull spanned by multiple virtual leaders under switching topologies regardless of fully unknown kinetic models. Through stability analyses, it is proven that the closed-loop control system is input-to-state stable and the tracking errors are uniformly ultimately bounded. Simulation results verify the effectiveness of the proposed cooperative control architecture for multiple underactuated USVs with fully unknown kinetic models.Constrained multiobjective optimization problems (CMOPs) involve both conflicting objective functions and various constraints. Due to the presence of constraints, CMOPs' Pareto-optimal solutions are very likely lying on constraint boundaries. The experience from the constrained single-objective optimization has shown that to quickly obtain such an optimal solution, the search should surround the boundary of the feasible region from both the feasible and infeasible sides. In this article, we extend this idea to cope with CMOPs and, accordingly, we propose a novel constrained multiobjective evolutionary algorithm with bidirectional coevolution, called BiCo. BiCo maintains two populations, that is 1) the main population and 2) the archive population. To update the main population, the constraint-domination principle is equipped with an NSGA-II variant to move the population into the feasible region and then to guide the population toward the Pareto front (PF) from the feasible side of the search space. While for updating the archive population, a nondominated sorting procedure and an angle-based selection scheme are conducted in sequence to drive the population toward the PF within the infeasible region while maintaining good diversity. As a result, BiCo can get close to the PF from two complementary directions. In addition, to coordinate the interaction between the main and archive populations, in BiCo, a restricted mating selection mechanism is developed to choose appropriate mating parents. Comprehensive experiments have been conducted on three sets of CMOP benchmark functions and six real-world CMOPs. The experimental results suggest that BiCo can obtain quite competitive performance in comparison to eight state-of-the-art-constrained multiobjective evolutionary optimizers.Spectral-domain optical coherence tomography (SD-OCT) images inevitably suffer from multiplicative speckle noise caused by random interference. This study proposes an unsupervised domain adaptation approach for noise reduction by translating the SD-OCT to the corresponding high-quality enhanced depth imaging (EDI)-OCT. We propose a structure-persevered cycle-consistent generative adversarial network for unpaired image-to-image translation, which can be applied to imbalanced unpaired data, and can effectively preserve retinal details based on a structure-specific cross-domain description. Abemaciclib It also imposes smoothness by penalizing the intensity variation of the low reflective region between consecutive slices. Our approach was tested on a local data set that consisted of 268 SD-OCT volumes and two public independent validation datasets including 20 SD-OCT volumes and 17 B-scans, respectively. Experimental results show that our method can effectively suppress noise and maintain the retinal structure, compared with other traditional approaches and deep learning methods in terms of qualitative and quantitative assessments. Our proposed method shows good performance for speckle noise reduction and can assist downstream tasks of OCT analysis.The presence of necrosis is associated with tumor progression and patient outcomes in many cancers, but existing analyses rarely adopt quantitative methods because the manual quantification of histopathological features is too expensive. We aim to accurately identify necrotic regions on hematoxylin and eosin (HE)stained slides and to calculate the ratio of necrosis with minimal annotations on the images. An adaptive method named Learning from Label Fuzzy Proportions (LLFP) was introduced to histopathological image analysis. Two datasets of liver cancer HE slides were collected to verify the feasibility of the method by training on the internal set using cross validation and performing validation on the external set, along with ensemble learning to improve performance. The models from cross validation performed relatively stably in identifying necrosis, with a Concordance Index of the Slide Necrosis Score (CISNS) of 0.91650.0089 in the internal test set. The integration model improved the CISNS to 0.9341 and achieved a CISNS of 0.8278 on the external set. There were significant differences in survival (p=0.0060) between the three groups divided according to the calculated necrosis ratio. The proposed method can build an integration model good at distinguishing necrosis and capable of clinical assistance as an automatic tool to stratify patients with different risks or as a cluster tool for the quantification of histopathological features. We presented a method effective for identifying histopathological features and suggested that the extent of necrosis, especially micronecrosis, in liver cancer is related to patient outcomes.The Cox proportional hazards model is one of the most widely used methods for analyzing survival data. Data from multiple data providers are required to improve the generalizability and confidence of the results of Cox analysis; however, such data sharing may result in leakage of sensitive information, leading to financial fraud, social discrimination or unauthorized data abuse. Some privacy-preserving Cox regression protocols have been proposed in past years, but they lack either security or functionality. In this paper, we propose a privacy-preserving Cox regression protocol for multiple data providers and researchers. The proposed protocol allows researchers to train models on horizontally or vertically partitioned datasets while providing privacy protection for both the sensitive data and the trained models. Our protocol utilizes threshold homomorphic encryption to guarantee security. Experimental results demonstrate that with the proposed protocol, Cox regression model training over 9 variables in a dataset of 113,035 samples takes approximately 44 min, and the trained model is almost the same as that obtained with the original nonsecure Cox regression protocol; therefore, our protocol is a potential candidate for practical real-world applications in multicenter medical research.Efficient modeling of feature interactions underpins supervised learning for nonsequential tasks, characterized by a lack of inherent ordering of features (variables). The brute force approach of learning a parameter for each interaction of every order comes at an exponential computational and memory cost (curse of dimensionality). To alleviate this issue, it has been proposed to implicitly represent the model parameters as a tensor, the order of which is equal to the number of features; for efficiency, it can be further factorized into a compact tensor train (TT) format. However, both TT and other tensor networks (TNs), such as tensor ring and hierarchical Tucker, are sensitive to the ordering of their indices (and hence to the features). To establish the desired invariance to feature ordering, we propose to represent the weight tensor through the canonical polyadic (CP) decomposition (CPD) and introduce the associated inference and learning algorithms, including suitable regularization and initialization schemes. It is demonstrated that the proposed CP-based predictor significantly outperforms other TN-based predictors on sparse data while exhibiting comparable performance on dense nonsequential tasks. Furthermore, for enhanced expressiveness, we generalize the framework to allow feature mapping to arbitrarily high-dimensional feature vectors. In conjunction with feature vector normalization, this is shown to yield dramatic improvements in performance for dense nonsequential tasks, matching models such as fully connected neural networks.Many spatiotemporal events can be viewed as contagions. These events implicitly propagate across space and time by following cascading patterns, expanding their influence, and generating event cascades that involve multiple locations. Analyzing such cascading processes presents valuable implications in various urban applications, such as traffic planning and pollution diagnostics. Motivated by the limited capability of the existing approaches in mining and interpreting cascading patterns, we propose a visual analytics system called VisCas. VisCas combines an inference model with interactive visualizations and empowers analysts to infer and interpret the latent cascading patterns in the spatiotemporal context. To develop VisCas, we address three major challenges, 1) generalized pattern inference, 2) implicit influence visualization, and 3) multifaceted cascade analysis. For the first challenge, we adapt the state-of-the-art cascading network inference technique to general urban scenarios, where cascading patterns can be reliably inferred from large-scale spatiotemporal data. For the second and third challenges, we assemble a set of effective visualizations to support location navigation, influence inspection, and cascading exploration, and facilitate the in-depth cascade analysis. We design a novel influence view based on a three-fold optimization strategy for analyzing the implicit influences of the inferred patterns. We demonstrate the capability and effectiveness of VisCas with two case studies conducted on real-world traffic congestion and air pollution datasets with domain experts.Recent advances in deep convolution neural networks (CNNs) boost the development of video salient object detection (SOD), and many remarkable deep-CNNs video SOD models have been proposed. However, many existing deep-CNNs video SOD models still suffer from coarse boundaries of the salient object, which may be attributed to the loss of high-frequency information. The traditional graph-based video SOD models can preserve object boundaries well by conducting superpixels/supervoxels segmentation in advance, but they perform weaker in highlighting the whole object than the latest deep-CNNs models, limited by heuristic graph clustering algorithms. To tackle this problem, we find a new way to address this issue under the framework of graph convolution networks (GCNs), taking advantage of graph model and deep neural network. Specifically, a superpixel-level spatiotemporal graph is first constructed among multiple frame-pairs by exploiting the motion cues implied in the frame-pairs. Then the graph data is imported into the devised multi-stream attention-aware GCN, where a novel Edge-Gated graph convolution (GC) operation is proposed to boost the saliency information aggregation on the graph data.
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