Notes

Ailment reputation is related to particular autobiographical memory space loss within alcohol-dependence.
Finally, all the hub genes of ARS were proved to be upregulated in EC tissues by immunohistology.

ARS can be used to stratify the risk and forecast the survival outcome of EC patients and provide prominent reference for individualized treatment in EC.
ARS can be used to stratify the risk and forecast the survival outcome of EC patients and provide prominent reference for individualized treatment in EC.
Neuroblastoma is a common solid tumor originating from the sympathetic nervous system, commonly found in children, and it is one of the leading causes of tumor-related deaths in children. In addition to pathological features, molecular-level features, such as how much gene expression is present and the mutational profile, may provide useful information for the precise treatment of neuroblastoma. Transcription factors (TFs) play an important regulatory role in all aspects of cellular life activities. But there are currently no studies on transcription factor-based biomarkers of neuroblastoma prognosis, and this study is much needed.

We downloaded RNA transcriptome data and clinical data from the TARGET database to construct a prognostic model. The prognostic model was constructed by using univariate Cox analysis, LASSO, and multivariate Cox regression. We divided the patients into low-risk and high-risk groups using the median value of the risk score as the cut-off. Then, we validated the prognostic model e new potential targets for the treatment of neuroblastoma and personalized monitoring of neuroblastoma patients with high and low risk.There are some problems in the process of video intelligent description and analysis of volleyball, such as poor effective information extraction rate and poor dynamic tracking effect. Based on this, combined with long-term and short-term memory network and attention mechanism, this paper designs an intelligent description model of volleyball video based on deep learning algorithm and studies how to improve the extraction rate of volleyball video information through intelligent detection hardware and image recognition technology. This paper first introduces the application of image recognition technology and deep learning algorithm in the intelligent description of volleyball video, then designs the volleyball video and image recognition model based on deep learning algorithm according to the requirements of volleyball video intelligent description, and selects three correlation factors related to the impact indicators of volleyball skills. This study selects three characteristic parameters associated with volleyball video analysis indexes, namely, take-off, bounce, and hand movement, combined with image sensing hardware assisted sensor network to realize real-time monitoring of action state in volleyball video analysis system. The experimental results show that, compared with the current mainstream sports video intelligent analysis and image recognition methods with data analysis as the core, the intelligent volleyball sports video intelligent description and image recognition system based on the integration of deep learning algorithm and sensor hardware assistance has the advantages of good detection effect, high data effectiveness, low cost, and high efficiency of volleyball sports video analysis. It can effectively improve the efficiency of volleyball video intelligent description.The marine predators algorithm (MPA) is a novel population-based optimization method that has been widely used in real-world optimization applications. However, MPA can easily fall into a local optimum because of the lack of population diversity in the late stage of optimization. To overcome this shortcoming, this paper proposes an MPA variant with a hybrid estimation distribution algorithm (EDA) and a Gaussian random walk strategy, namely, HEGMPA. The initial population is constructed using cubic mapping to enhance the diversity of individuals in the population. Then, EDA is adapted into MPA to modify the evolutionary direction using the population distribution information, thus improving the convergence performance of the algorithm. In addition, a Gaussian random walk strategy with medium solution is used to help the algorithm get rid of stagnation. The proposed algorithm is verified by simulation using the CEC2014 test suite. Simulation results show that the performance of HEGMPA is more competitive than other comparative algorithms, with significant improvements in terms of convergence accuracy and convergence speed.Accurate identification of high-frequency oscillation (HFO) is an important prerequisite for precise localization of epileptic foci and good prognosis of drug-refractory epilepsy. Exploring a high-performance automatic detection method for HFOs can effectively help clinicians reduce the error rate and reduce manpower. Due to the limited analysis perspective and simple model design, it is difficult to meet the requirements of clinical application by the existing methods. Therefore, an end-to-end bi-branch fusion model is proposed to automatically detect HFOs. With the filtered band-pass signal (signal branch) and time-frequency image (TFpic branch) as the input of the model, two backbone networks for deep feature extraction are established, respectively. Specifically, a hybrid model based on ResNet1d and long short-term memory (LSTM) is designed for signal branch, which can focus on both the features in time and space dimension, while a ResNet2d with a Convolutional Block Attention Module (CBAM) is constructed for TFpic branch, by which more attention is paid to useful information of TF images. Then the outputs of two branches are fused to realize end-to-end automatic identification of HFOs. Our method is verified on 5 patients with intractable epilepsy. In intravalidation, the proposed method obtained high sensitivity of 94.62%, specificity of 92.7%, and F1-score of 93.33%, and in cross-validation, our method achieved high sensitivity of 92.00%, specificity of 88.26%, and F1-score of 89.11% on average. The results show that the proposed method outperforms the existing detection paradigms of either single signal or single time-frequency diagram strategy. In addition, the average kappa coefficient of visual analysis and automatic detection results is 0.795. The method shows strong generalization ability and high degree of consistency with the gold standard meanwhile. Therefore, it has great potential to be a clinical assistant tool.Recently, many deep learning models have archived high results in question answering task with overall F1 scores above 0.88 on SQuAD datasets. However, many of these models have quite low F1 scores on why-questions. These F1 scores range from 0.57 to 0.7 on SQuAD v1.1 development set. This means these models are more appropriate to the extraction of answers for factoid questions than for why-questions. Why-questions are asked when explanations are needed. These explanations are possibly arguments or simply subjective opinions. Therefore, we propose an approach to finding the answer for why-question using discourse analysis and natural language inference. In our approach, natural language inference is applied to identify implicit arguments at sentence level. It is also applied in sentence similarity calculation. Protoporphyrin IX molecular weight Discourse analysis is applied to identify the explicit arguments and the opinions at sentence level in documents. The results from these two methods are the answer candidates to be selected as the final answer for each why-question. We also implement a system with our approach. Our system can provide an answer for a why-question and a document as in reading comprehension test. We test our system with a Vietnamese translated test set which contains all why-questions of SQuAD v1.1 development set. The test results show that our system cannot beat a deep learning model in F1 score; however, our system can answer more questions (answer rate of 77.0%) than the deep learning model (answer rate of 61.0%).Ovarian cancer is the third most common gynecologic cancers worldwide. Advanced ovarian cancer patients bear a significant mortality rate. Survival estimation is essential for clinicians and patients to understand better and tolerate future outcomes. The present study intends to investigate different survival predictors available for cancer prognosis using data mining techniques. Dataset of 140 advanced ovarian cancer patients containing data from different data profiles (clinical, treatment, and overall life quality) has been collected and used to foresee cancer patients' survival. Attributes from each data profile have been processed accordingly. Clinical data has been prepared corresponding to missing values and outliers. Treatment data including varying time periods were created using sequence mining techniques to identify the treatments given to the patients. And lastly, different comorbidities were combined into a single factor by computing Charlson Comorbidity Index for each patient. After appropriate preprocessing, the integrated dataset is classified using appropriate machine learning algorithms. The proposed integrated model approach gave the highest accuracy of 76.4% using ensemble technique with sequential pattern mining including time intervals of 2 months between treatments. Thus, the treatment sequences and, most importantly, life quality attributes significantly contribute to the survival prediction of cancer patients.In order to improve software quality and testing efficiency, this paper implements the prediction of software defects based on deep learning. According to the respective advantages and disadvantages of the particle swarm algorithm and the wolf swarm algorithm, the two algorithms are mixed to realize the complementary advantages of the algorithms. At the same time, the hybrid algorithm is used in the search of model hyperparameter optimization, the loss function of the model is used as the fitness function, and the collaborative search ability of the swarm intelligence population is used to find the global optimal solution in multiple local solution spaces. Through the analysis of the experimental results of six data sets, compared with the traditional hyperparameter optimization method and a single swarm intelligence algorithm, the model using the hybrid algorithm has higher and better indicators. And, under the processing of the autoencoder, the performance of the model has been further improved.Intrinsically disordered proteins (IDPs) possess at least one region that lacks a single stable structure in vivo, which makes them play an important role in a variety of biological functions. We propose a prediction method for IDPs based on convolutional neural networks (CNNs) and feature selection. The combination of sequence and evolutionary properties is used to describe the differences between disordered and ordered regions. Especially, to highlight the correlation between the target residue and adjacent residues, multiple windows are selected to preprocess the protein sequence through the selected properties. The shorter windows reflect the characteristics of the central residue, and the longer windows reflect the characteristics of the surroundings around the central residue. Moreover, to highlight the specificity of sequence and evolutionary properties, they are preprocessed, respectively. After that, the preprocessed properties are combined into feature matrices as the input of the constructed CNN. Our method is training as well as testing based on the DisProt database.
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