Notes

A singular Genetic Variant within the WFS1 Gene in the Affected individual along with Partially Uniparental Mero-Isodisomy involving Chromosome Some.
The experimental results demonstrate that the proposed algorithm achieves higher attack detection accuracy of 99.5% and 99.9% for DDoS and car hacks, respectively. The other performance scores, precision, recall, and F1-score, also verify the superior performance of the proposed framework.As an important field of computer vision, object detection has been studied extensively in recent years. However, existing object detection methods merely utilize the visual information of the image and fail to mine the high-level semantic information of the object, which leads to great limitations. To take full advantage of multi-source information, a knowledge update-based multimodal object recognition model is proposed in this paper. Specifically, our method initially uses Faster R-CNN to regionalize the image, then applies a transformer-based multimodal encoder to encode visual region features (region-based image features) and textual features (semantic relationships between words) corresponding to pictures. After that, a graph convolutional network (GCN) inference module is introduced to establish a relational network in which the points denote visual and textual region features, and the edges represent their relationships. In addition, based on an external knowledge base, our method further enhances the region-based relationship expression capability through a knowledge update module. In summary, the proposed algorithm not only learns the accurate relationship between objects in different regions of the image, but also benefits from the knowledge update through an external relational database. Experimental results verify the effectiveness of the proposed knowledge update module and the independent reasoning ability of our model.A MEMS directional acoustic sensor housed in an air cavity and operated underwater in a near-neutral buoyancy configuration is demonstrated. The sensor consists of two wings connected by a bridge and attached to a substrate by two centrally mounted torsional legs. The frequency response showed two resonant peaks corresponding to a rocking mode (wings moving in opposite directions) and a bending mode (wings moving in the same direction). Initial tests of the sensor using a shaker table showed that the response is highly dependent on the vibration direction. In air, the sensor showed a maximum sensitivity of about 95 mV/Pa with a cosine directional response. Underwater, the maximum sensitivity was about 37 mV/Pa with a similar cosine directional response. The measured maximum SNR was about 38 dB for a signal generated by a sound stimulus of 1 Pa when the sensor is operated near the bending resonance. The results indicate that this type of MEMS sensor can be operated in a near-neutral buoyant configuration and achieve a good directional response.This paper presents a novel computational algorithm to estimate blood volume decompensation state based on machine learning (ML) analysis of multi-modal wearable-compatible physiological signals. To the best of our knowledge, our algorithm may be the first of its kind which can not only discriminate normovolemia from hypovolemia but also classify hypovolemia into absolute hypovolemia and relative hypovolemia. We realized our blood volume classification algorithm by (i) extracting a multitude of features from multi-modal physiological signals including the electrocardiogram (ECG), the seismocardiogram (SCG), the ballistocardiogram (BCG), and the photoplethysmogram (PPG), (ii) constructing two ML classifiers using the features, one to classify normovolemia vs. hypovolemia and the other to classify hypovolemia into absolute hypovolemia and relative hypovolemia, and (iii) sequentially integrating the two to enable multi-class classification (normovolemia, absolute hypovolemia, and relative hypovolemia). We developed the blood volume decompensation state classification algorithm using the experimental data collected from six animals undergoing normovolemia, relative hypovolemia, and absolute hypovolemia challenges. Leave-one-subject-out analysis showed that our classification algorithm achieved an F1 score and accuracy of (i) 0.93 and 0.89 in classifying normovolemia vs. hypovolemia, (ii) 0.88 and 0.89 in classifying hypovolemia into absolute hypovolemia and relative hypovolemia, and (iii) 0.77 and 0.81 in classifying the overall blood volume decompensation state. The analysis of the features embedded in the ML classifiers indicated that many features are physiologically plausible, and that multi-modal SCG-BCG fusion may play an important role in achieving good blood volume classification efficacy. Our work may complement existing computational algorithms to estimate blood volume compensatory reserve as a potential decision-support tool to provide guidance on context-sensitive hypovolemia therapeutic strategy.Ensuring security for modern IoT systems requires the use of complex methods to analyze their software. One of the most in-demand methods that has repeatedly been proven to be effective is static analysis. However, the progressive complication of the connections in IoT systems, the increase in their scale, and the heterogeneity of elements requires the automation and intellectualization of manual experts' work. A hypothesis to this end is posed that assumes the applicability of machine-learning solutions for IoT system static analysis. A scheme of this research, which is aimed at confirming the hypothesis and reflecting the ontology of the study, is given. The main contributions to the work are as follows systematization of static analysis stages for IoT systems and decisions of machine-learning problems in the form of formalized models; review of the entire subject area publications with analysis of the results; confirmation of the machine-learning instrumentaries applicability for each static analysis stage; and the proposal of an intelligent framework concept for the static analysis of IoT systems. The novelty of the results obtained is a consideration of the entire process of static analysis (from the beginning of IoT system research to the final delivery of the results), consideration of each stage from the entirely given set of machine-learning solutions perspective, as well as formalization of the stages and solutions in the form of "Form and Content" data transformations.Despite hard sensors can be easily used in various condition monitoring of energy production process, soft sensors are confined to some specific scenarios due to difficulty installation requirements and complex work conditions. However, industrial process may refer to complex control and operation, the extraction of relevant information from abundant sensors data may be challenging, and description of complicated process data patterns is also becoming a hot topic in soft-sensor development. In this paper, a hybrid soft sensor model based mechanism analysis and data-driven is proposed, and ventilation sensing of coal mill in a power plant is conducted as a case study. Firstly, mechanism model of ventilation is established via mass and energy conservation law, and object-relevant features are identified as the inputs of data-driven method. Secondly, radial basis function neural network (RBFNN) is used for soft sensor modeling, and genetic algorithm (GA) is adopted for quick and accurate determination of the RBFNN hyper-parameters, thus self-adaptive RBFNN (SA-RBFNN) is proposed to improve the soft sensor performance in energy production process. Finally, effectiveness of the proposed method is verified on a real-world power plant dataset, taking coal mill ventilation soft sensing as a case study.Fetal acidosis is one of the main concerns during labor. Currently, fetal blood sampling (FBS) has become the most accurate measurement of acidosis detection. However, it is invasive and does not provide a real time measurement due to laboratory procedures. Delays in diagnosis of acidosis have caused serious injury to the fetus, especially for the brain and the heart. This paper reviews the new technique in diagnosis of acidosis non-invasively. this website Magnetic Induction Spectroscopy (MIS) has been proposed to be a new device for acidosis detection in recent years. This paper explains the basic principle of MIS and outlines the design specifications and design considerations for a MIS pH probe. It is expected that readers will gain a basic understanding of the development of a MIS pH probe from this review.Spinal mobility assessment is essential for the diagnostic of patients with ankylosing spondylitis. BASMI is a routine clinical evaluation of the spine; its measurements are made with goniometers and tape measures, implying systematic errors, subjectivity, and low sensitivity. Therefore, it is crucial to develop better mobility assessment methods. The design, implementation, and evaluation of a novel system for assessing the entire spine's motion are presented. It consists of 16 magnetic and inertial measurement units (MIMUs) communicated wirelessly with a computer. The system evaluates the patient's movements by implementing a sensor fusion of the triaxial gyroscope, accelerometer, and magnetometer signals using a Kalman filter. Fifteen healthy participants were assessed with the system through six movements involving the entire spine to calculate continuous kinematics and maximum range of motion (RoM). The intrarater reliability was computed over the observed RoM, showing excellent reliability levels (intraclass correlation >0.9) in five of the six movements. The results demonstrate the feasibility of the system for further clinical studies with patients. The system has the potential to improve the BASMI method. To the best of our knowledge, our system involves the highest number of sensors, thus providing more objective information than current similar systems.Understanding hand and wrist forces during activities of daily living (ADLs) are pertinent when modeling prosthetics/orthotics, preventing workplace-related injuries, and understanding movement patterns that make athletes, dancers, and musicians elite. The small size of the wrist, fingers, and numerous joints creates obstacles in accurately measuring these forces. In this study, 14 FlexiForce sensors were sewn into a glove in an attempt to capture forces applied by the fingers. Participants in this study wore the glove and performed grasp and key turn activities. The maximal forces produced in the study were 9 N at the distal middle finger phalanx and 24 N at the distal thumb phalanx, respectively, for the grasp and key turn activities. Results from this study will help in determining the minimal forces of the hand during ADLs so that appropriate actuators may be placed at the appropriate joints in exoskeletons, orthotics, and prosthetics.The location of trees and the individualization of their canopies are important parameters to estimate diameter, height, and biomass, among other variables. The very high spatial resolution of UAV imagery supports these processes. A dense 3D point cloud is generated from RGB UAV images, which is used to obtain a digital elevation model (DEM). From this DEM, a canopy height model (CHM) is derived for individual tree identification. Although the results are satisfactory, the quality of this detection is reduced if the working area has a high density of vegetation. The objective of this study was to evaluate the use of color vegetation indices (CVI) in canopy individualization processes of Pinus radiata. UAV flights were carried out, and a 3D dense point cloud and an orthomosaic were obtained. Then, a CVI was applied to 3D point cloud to differentiate between vegetation and nonvegetation classes to obtain a DEM and a CHM. Subsequently, an automatic crown identification procedure was applied to the CHM. The results were evaluated by contrasting them with results of manual individual tree identification on the UAV orthomosaic and those obtained by applying a progressive triangulated irregular network to the 3D point cloud.
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