Notes

Addition of docetaxel or abiraterone in order to androgen starvation treatment in metastatic hormone-sensitive cancer of prostate inside American indian populace.
Endoscopic retrograde cholangiopancreatography (ERCP) combined with clinical features confirmed a diagnosis of BBF. Both patients recovered after treatment and were discharged from the hospital. The clinical diagnosis of BBF largely relies upon imaging combined with clinical standards, and BALF examinations are rarely performed. This current investigation retrospectively analyzed the diagnosis and treatment of two cases of BBF, and demonstrated that bilirubin crystallization in the BALF may be an important diagnostic indicator for BBF.Coronavirus disease 2019 (COVID-19), an acute infectious disease, which is characterized by influenza, fever, cough and dyspnea. APR-246 supplier Up to now, the pathogenic mechanism and radical cure treatment for COVID-19 are still unknown. However, COVID-19 could lead to pneumonia, multiple organ failure and even death with disease development. During the period of February 10 and March 26, 2020, we admitted and treated three COVID-19 patients complicated with acute myocardial infarction. As we all know, acute myocardial infarction is a kind of disease that induces myocardial ischemia necrosis and leads to high mortality. Through the three COVID-19 patients complicated with acute myocardial infarction, we have strengthened our nursing experience. Thus, we wish to share our nursing experience with these cases by analyzing the etiology of three patients with coronavirus disease 2019 (COVID-19) complicated with acute myocardial infarction in this paper. First, we retrospectively analyzed the clinical data, including patient complaints, diagnosis, treatment, and prognosis, of three patients with COVID-19 complicated with acute myocardial infarction admitted to Ward II, Department of Infectious Diseases III, Huoshenshan Hospital, Wuhan, Hubei Province, China, between February 10 and March 26, 2020. Then, we searched for relevant literature, analyzed etiology, and summarized the nursing measures taken. For COVID-19 patients with a high risk of acute myocardial infarction, nurses should stay vigilant, closely monitor any change in condition, and implement early measures to maintain vital signs and enable timely visits with specialists. Finally, we importantly found that these nursing measures are keys to managing the patient's condition, improving patient outcomes, and increasing the chance of treatment success.
This article summarizes the research progress on the association of dietary habits with esophageal cancer (EC), with the aim of gaining a better understanding of lifestyle, dietary, and drug-related risk factors as well as protective factors of EC.

EC is one of the most common malignant cancers and has a high mortality rate. Evidence has suggested that dietary habits are closely related to EC. Several researches refer to the issue of the relationship between dietary habits and EC, but rare of them summary systematically and comprehensively. It is of great importance to study the role of dietary habits in the etiology of EC for the prevention and treatment of this disease.

We searched the China National Knowledge Infrastructure (CNKI), PubMed, Medline and EMBASE databases to identify studies on the association of dietary habits with EC published between the databases' dates of inception and March 2021.

This comprehensive review summarizes the state-of-the-art research findings on the association between dietary habits and EC, with the literature we obtained revealing that dietary habits have been increasingly regarded as potential etiologies or protective factors of EC, which reinforce the importance of suitable planning of interventions to reduce the burden of this disease among the population.
This comprehensive review summarizes the state-of-the-art research findings on the association between dietary habits and EC, with the literature we obtained revealing that dietary habits have been increasingly regarded as potential etiologies or protective factors of EC, which reinforce the importance of suitable planning of interventions to reduce the burden of this disease among the population.
Knee osteoarthritis (KOA) is a common joint disease worldwide, and the main cause of pain and disability in the elderly. Due to increased aging and rates of obesity of the global population, the number of patients with KOA is expected to increase. To reduce the burden of KOA, effective and safe interventions should be developed to reduce pain and improve range of motion, functionality, and quality of life. The aim of the proposed randomized controlled study was to evaluate the efficacy and safety of a traditional Chinese medicine (TCM) rehabilitation therapy in the treatment of KOA.

This multicenter, randomized, double-blind, parallel group, placebo-controlled trial will include a total of 200 patients with KOA. The enrolled patients will be randomly divided into the experimental group (n=100) and control group (n=100). The experimental group will receive basic treatment plus TCM rehabilitation therapy, while the control group will receive basic treatment plus physiotherapy regimen. Primary endpoints will include clinical efficacy outcomes, visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index score, and Knee Outcome Survey Activities of Daily Living Scale score. The data will help determine whether TCM rehabilitation therapy is beneficial for the treatment of KOA.

The results will provide high-quality guidance for the current clinical treatment of KOA, and provide patients with more options for symptom relief. The findings from this study may provide updated evidence concerning the efficacy and safety of TCM for patients with KOA.
The results will provide high-quality guidance for the current clinical treatment of KOA, and provide patients with more options for symptom relief. The findings from this study may provide updated evidence concerning the efficacy and safety of TCM for patients with KOA.
Central nervous system injury (CNSI) comprises a series of common diseases that severely affect patients' motor function and quality of life and is associated with high disability and mortality rates. Previous studies have shown that contralateral lumbosacral nerve root transfer significantly improved the function of the paralyzed limb in rat models of CNSI. These studies showed that severing the sacral 1 nerve root (S1) did not damage the function of the ipsilateral lower extremity. Thus, we speculate that contralateral S1 nerve root transfer can improve the recovery of a paralyzed limb. Because no associated rigorously designed randomized controlled trial has evaluated the effectiveness of contralateral S1 nerve transfer thus far, we designed this clinical trial to compare the effects of this new treatment approach with those of traditional treatments in paralyzed patients after chronic CNSI.

This is a single-center, prospective, randomized controlled trial. Forty patients, who meet the inclusion criteria and have hemiplegia caused by chronic CNSI, will be randomly divided into the surgical or non-surgical group.
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