Notes

Evaluation about Harmful Effects of Di(2-ethylhexyl) Phthalate about Zebrafish Embryos.
8% is reduced to 3.11% in 2008 and 0.86% in 2017. The settlements increased from 15.59 to 24.21% in 2008 and 27.14% in 2017. Increase in deforestation leads to increase in barren land. In 1999, the percentage of barren land was 17.2%; in 2008, it was 13.19%, and 50.93% in 2017. The overall accuracy estimation of the study is 73.19% and Kappa coefficient is 0.72. This study has proven a substantial strength of agreement for the map of 2017 from the result of validation rating criteria of Kappa statistics.Nationally determined contributions were at the core of the Paris Agreement for the global response to climate change. However, with the geographical separation of production and consumption caused by international trade, traditional trade statistics can no longer accurately reflect the flows of economic value and carbon emissions between countries, which will affect the participation and implementation of global climate policies. Based on a multi-regional input-output model, we measured the embodied carbon flows of bilateral trade between developed countries represented by Germany and the US, discussed the decoupling relationship between embodied carbon and export-led growth, and finally used structural decomposition analysis (SDA) to show how the driving factors affect embodied carbon flow in German-US trade. We found that from 2000 to 2014, embodied carbon in German-US trade showed an overall downward trend. While Germany maintained a trade surplus with the US, it also maintained an embodied carbon surplus. In addition, embodied carbon and value added in Germany's exports to the US were mostly strongly decoupled, while in US exports to Germany were mostly weakly decoupled, and the two-way decoupling had been weakened in the later stage. The results of SDA showed that changes in carbon intensity clearly inhibited bilateral carbon flows, while trade scale effects promoted it. This study provided an opportunity to use trade to achieve carbon reduction and increased the possibility of providing a convenient and feasible market mechanism for emission reduction through international partnerships.Climate change influences the current tropospheric ozone (O3) budget due to industrialization and urbanization processes. In recent years, the impact of elevated O3 on crop development and yield loss has emerged as one of the most important environmental issues, particularly in rural and suburban areas of the lower Indo-Gangetic Plains of India. The impact of the current tropospheric ozone (O3) on the crop yield, photosynthetic yield, and enzymatic antioxidants of six rice (Oryza sativa L.) cultivars (IR 36, MTU 1010, GB 3, Khitish, IET 4786, and Ganga Kaveri) was investigated with and without the application of ethylenediurea (EDU). The results revealed that O3 stress significantly affected crop yield, photosynthetic yield, and antioxidant enzymes. The findings showed that O3 toxicity induces oxidative stress biomarkers, i.e., malondialdehyde (MDA) content, and was manifested by increasing the enzymatic antioxidants, i.e., superoxidase dismutase (SOD) and catalase (CAT) in four rice cultivars (IR 36, GB 3, IET 4786, and Ganga Kaveri). At the same time, the results also illustrated that the rice cultivars MTU 1010 and Khitish are more tolerant to O3 stress as they had less oxidative damage, greater photosynthetic SPAD value, SOD and CAT activities, and lower MDA activity. The results also elucidated that the application of EDU decreased O3 toxicity in sensitive cultivars of rice by increasing antioxidant defense systems. The current O3 level is likely to show an additional increase in the near future, and the use of tolerant genotypes of rice may reduce the negative impacts of O3 on rice production.Though the incidence of several cancers in Western societies is regulated wisely, some cancers such as breast, lung, and colorectal cancer are currently rising in many low- and middle-income countries due to increased risk factors triggered by societal and development problems. Surgery, chemotherapy, hormone, radiation, and targeted therapies are examples of traditional cancer treatment approaches. However, multiple short- and long-term adverse effects may also significantly affect patient prognosis depending on treatment-associated clinical factors. More and more research has been carried out to find new therapeutic agents in natural products, among which the bioactive compounds derived from plants have been increasingly studied. Naringin and naringenin are abundantly found in citrus fruits, such as oranges and grapefruits. A variety of cell signaling pathways mediates their anti-carcinogenic properties. Naringin and naringenin were also documented to overcome multidrug resistance, one of the major challenges to clinical practice due to multiple defense mechanisms in cancer. The effective parameters underlying the anticancer effects of naringenin and naringin include GSK3β inactivation, suppression of the gene and protein activation of NF-kB and COX-2, JAK2/STAT3 downregulation, downregulation of intracellular adhesion molecules-1, upregulation of Notch1 and tyrocite-specific genes, and activation of p38/MAPK and caspase-3. Thus, this review outlines the potential of naringin and naringenin in managing different types of cancers.Cancer is a growing global health threat. Examining the determinants of cancer incidence can benefit for cancer treatment and prevention. Farmland transfer relates to the risk factors of esophageal cancer including environmental pollution, services access, and habits. This study characterizes the associations between farmland transfer and esophageal cancer incidence rate (ECI) that integrate mediated effect of pollution-related agricultural input intensity in Xiaoshan District, China. The state-space model is employed to quantify the relationships among farmland transfer, pollution-related agricultural input intensity, and ECI. The results showed that (1) Total effects of the proportion of transferred farmland (TFA) area cause a reduction in the ECI. Besides, the total positive effects of the proportion of transferred farmland cultivated non-grain crop (NGC) and proportion of farmland transferred to non-farmer users (NFU) show a downward trend. (2) The raise of TFA can result in the reduction of chemical fertilizer use intensity. Meanwhile, the raise of NGC and NFU can result in the growth of pollution-related agricultural input intensity. But these increasing effects generally show a downward trend. (3) Increasing chemical fertilizer use intensity and pesticide use intensity results in the rise of esophageal cancer incidence rate as a whole. (4) In general, farmland transfer has positive direct effects on esophageal cancer incidence rate. (5) The average proportions of mediated effects in all state-space models are larger than 10%. These findings can raise land reform policy designers' awareness of the risk of public health since the land transfer markets are emerging rapidly in land reform in many developing countries to improve agricultural production.Here, conjugate of nano-graphene oxide (GO) and titanium dioxide nanoparticle (nTiO2) was proposed for the photocatalytic degradation of two toxic azo dyes, Congo red (CR) and Methylene blue (MB), under sunlight irradiation. Furthermore, the optimized weight ratio between GO and nTiO2 of 15 demonstrated the highest degradation efficiency. The nanoconjugate induced 85% degradation of 40 ppm of CR in 60 min and a complete degradation within 70 min, while it degraded more than 90% of 20 ppm of MB in 80 min. The photocatalyst can be reused for five cycles of photocatalysis. Thus, the photocatalytic potential of GO/nTiO2 under visible light may be used as a very suitable and cost-effective photocatalyst industrially for the removal of toxic dyes from water.The Yellow River is an important ecological shelter zone and economic belt in China. However, rapid urbanization and industrialization has produced a fragile ecological environment conditions and unbalanced economic development in the Yellow River Basin (YRB). Ecological protection and high-quality development of the YRB has been China's national strategy since 2019. As the only coastal province with the largest economy and population in the YRB, the sustainable development of Shandong Province is of great importance in the region. This study evaluated the dynamic trend of sustainability levels of the nine cities in Shandong Province in the YRB through emergy analysis. Emergy-based indicators were established and analyzed from 2010 to 2019, taking account of the ecological service emergy (ESE) needed to dilute pollutants and emergy equivalent loss (EEL) on ecosystem quality and human health damage. Results showed that emergy sustainable indicators (ESI) in Tai'an, Heze, Dezhou, and Liaocheng ranged from 1 to 10, which had the potential for sustainable development. The ESI value of Jinan, Jining, Zibo, Dongying, and Binzhou was less than 1, which indicated that these cities were under great ecological pressure. The value of emergy indicators for sustainable development (EISD) of the nine cities all declined from 2010 to 2016, but remained stable from 2017 to 2019. Based on findings from the emergy analysis regarding policy implications and local conditions, the study concludes by providing proposals to improve regional sustainability.Uniconazole is a widely used plant growth retardant in the agricultural field. However, toxicological effects of uniconazole in aquatic ecosystem at chiral level are still unclear. Herein, acute toxicity, oxidative stress effects, neurotoxicity, and thyroid disruption of uniconazole enantiomers were investigated through using zebrafish as a model. (R)-Uniconazole possessed 1.16-fold greater acute toxicity to zebrafish than (S)-enantiomer. Then, integrated biomarker response values of oxidative stress parameters in zebrafish exposed to (R)-uniconazole were about 1.27~1.53 times greater than those treated by (S)-uniconazole, revealing that (R)-uniconazole could result in more significant adverse effects than (S)-uniconazole. Subsequently, the results of acetylcholinesterase activity of experimental fish demonstrated a state of inhibition-activation-inhibition after 14-day exposure to uniconazole, and a significant enantioselective neurotoxicity of uniconazole was observed in zebrafish after exposure for 4 and 7 days (p less then 0.05). Moreover, thyroxine and triiodothyronine contents in (R)-uniconazole-exposed zebrafish were 0.89-fold (p=0.007) and 0.80-fold (p=0.007) than those in (S)-enantiomer-treated group, respectively. Furthermore, molecular docking results between uniconazole enantiomers and thyroid hormone receptors revealed that (R)-uniconazole was more tightly bound than (S)-uniconazole to the receptors. Briefly, our findings provide favorable information for ecological risk assessments of chiral agrochemicals in the environment and health of aquatic organisms.Stressing agents can cause morphophysiological and behavioural changes in several animals, including birds, which are good study models for environmental biomonitoring. The heterophil/lymphocyte ratio (H/L) is an efficient indicator of chronic stresses in birds. In this study, we aimed to compare the H/L ratio of birds between the areas with different levels of urbanisation, anthropogenic noise and carbon monoxide (CO) emission rates. A total of 1288 birds were captured in six Cerrado forest fragments between 2013 and 2019, from which we took blood samples to produce blood smears. NSC-2260804 In each of these fragments, the noise level was measured with a sound pressure level metre. The CO rates were obtained from the National Institute for Space Research database (INPE-Brazil). There was a higher H/L ratio in individuals captured in urban areas or close to urbanisation with high anthropogenic noise levels and high CO rates, and a lower H/L ratio in individuals from preserved areas, far from urban environments with low noise levels and low CO rates.
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