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Life-cycle review associated with animal-based food and also plant-based protein-rich alternatives: a green viewpoint.
George's Respiratory Questionnaire (SGRQ), respectively. MT group had significantly greater improvement in FEV1%, FVC%, PEF%, respiratory muscle strength, function, dyspnea, fatigue, and quality of life compared with IMT group (p  less then  0.05). 6MWT (p  less then  0.001, effect size Cohen's d 0.915), MIP (p  less then  0.001, effect size Cohen's d 1.235), and mMRC score (p  less then  0.001, effect size Cohen's d 0.982) were significantly improved in IMT with MT group. This study demonstrated that subjects in IMT with MT group had improved outcomes in functional capacity, respiratory muscle strength, pulmonary function, dyspnea, fatigue perception, and quality of life compared with alone IMT group.
To explore the diagnostic value of radiomics in differentiating between lung adenocarcinomas appearing as ground-glass opacity nodules (GGO) with high- and low Ki-67 expression levels.

From January 2018 to January 2021, patients with pulmonary GGO who received lung resection were evaluated for potential enrollment. The included GGOs were then randomly divided into a training cohort and a validation cohort with a ratio of 73. Logistic regression (LR), decision tree (DT), support vector machines (SVM), and adaboost (AB) were applied for radiomic model construction. Area under the curve (AUC) of the receiver operating characteristic (ROC) curve was used to evaluate the diagnostic efficacy of the established models.

Seven hundred and sixty-nine patients with 769 GGOs were included in this study. Two hundred and forty-five GGOs were confirmed to be of high Ki-67 labeling index (LI). In the training cohort, gender, age, spiculation sign, pleural indentation sign, bubble sign, and maximum 2D diameter of the noradiomic model exhibited good diagnostic efficacy in differentiating between lung adenocarcinoma GGOs with high and low Ki-67 LI, which was higher than the clinical-radiographic model. Peri-nodular radiomic features showed added benefits to the radiomic model. As a novel noninvasive method, radiomics have the potential to be applied in the preliminary classification of Ki-67 expression level in lung adenocarcinoma GGOs.This study aims to assess the environmental impacts and the energy efficiency of organic and conventional vegetable production in Palas Basin, Kayseri, Turkey. Three organic and three conventional farmers representing the vegetable production in the region participated in face-to-face questionnaires. Life cycle assessment (LCA) was implemented to assess the global warming potential (GWP), eutrophication potential (EP), acidification potential (AP), and energy use, which were selected as environmental impact potentials. Additionally, the environmental risk assessment was conducted to understand the impact of pesticide use in the region. Six farmers were investigated individually, and it was found that all of the farmers had a common cultivation calendar, but there were differences in the application. Particularly, mineral fertilizer use and irrigation were excessive in some agricultural practices. Although the use of N- and P-based mineral fertilizers was one of the main differences between organic and conventional farming, irrigation was a common practice. Irrigation, the most influential practice, elevated not only water consumption but also EP, AP, and GWP as a result of electricity consumption by electrical pumps. Electricity consumption from irrigation contributed to the GWP most, and this value was in the range of 45%-95%. Mineral fertilizer use covered up to 40% of the EP, 31% of the GWP, and 37% of the AP for conventional farmers. Three different scenarios were developed to reduce the environmental impacts of the use of excessive mineral fertilizer and irrigation. The developed scenarios recommended the reductions by 38%, 44%, 25%, and 60% in GWP, EP, AP, and total energy inputs, respectively. This study demonstrates that LCA is beneficial in determining the environmental impact of hotspots in vegetable production and allows the development of different solutions to mitigate environmental impacts for agricultural sustainability. Integr Environ Assess Manag 2022;181733-1746. © 2022 SETAC.The object was to conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) up to the present to draw reliable conclusions in the comparison between short-term outcomes of total hip arthroplasty (THA) through supercapsular percutaneously assisted approach in THA (supercapsular percutaneously-assisted total hip (SuperPATH)) versus conventional approaches (CAs). A systematic literature search was performed to identify RCTs comparing primary and secondary outcomes of THA through SuperPATH vs. CAs. Mean differences (MDs) were calculated for continuous outcomes and odds ratios (ORs) for dichotomous outcomes, using the DerSimonian and Laird method, the Mantel-Haenszel method and random effects model. A total of 14 RCTs involving 1021 patients met the inclusion criteria. Primary outcomes SuperPATH reduced intraoperative blood loss (MD = -61.4, 95% CI -119.1 to -3.8). SuperPATH increased Harris hip score (HHS) 3, 6 and 12 months postoperatively (MD = 2.4, 95% CI 0.6-4.2; MD = 2.1, 95% CI 0.d sufficient results in acetabular cup positioning. CAs had a shorter operation time than SuperPATH.Adv. Healthcare Mater. 2016, 5, 1447-1461 DOI 10.1002/adhm.201600169 The above article, published online on 29 April 2016 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor-in-Chief, Dr. Uta Goebel, and Wiley-VCH GmbH. Concerns about figures within this article were raised by a reader in 2021, which has led to two Corrections of this article published on 20 January 2021[1] and 21 October 2021,[2] respectively. Subsequently, further concerns were raised about another figure within the article and an investigation of these new concerns indicated that there have been some modifications of the figures that cannot easily be explained. As a result, the journal is unable to determine whether the results and conclusions are valid and so have made the decision to retract the article. [1] F. Z. Dahmani, Y. Xiao, J. Zhang, Y. Yu, J. Zhou, J. Yao, Adv. Healthcare Mater. 2021, 10, 2002223. [2] F. Z. Dahmani, Y. Xiao, J. Zhang, Y. Yu, J. Zhou, J. Yao, Adv. Healthcare Mater. 2021, 10, 2101501.The influenza A virus of the H7N9 subtype (FLUAV H7N9) emerged in Eastern China provinces in 2013 causing illness in both poultry and humans. Most reported FLUAV H7N9 human cases were related to those associated with the live poultry market chain. From 2013 to 2017, there were five epidemic waves of human infections, and from the end of 2016, the number of human cases increased sharply. learn more To control FLUAV H7N9 in the market chain, the so-called '1110' policy at live poultry markets and a national vaccination programme were implemented. The relative efficacy of these two measures on the number of poultry and human infections has not been quantified and compared. To explore their efficacy, a cross-sectional study was conducted in six provinces of China, and the vaccination and surveillance data of H7N9 were analysed. Our survey data showed that poultry vendors were not widely aware of and did not accept the '1110' policy. For subjective and objective factors, some measures of the '1110' policy were not implemented in live bird markets (LBMs). However, the national vaccination programme achieved good immune effects and sharply decreased poultry FLUAV H7N9 infections. The detection rates of FLUAV H7N9 in LBMs and farms gradually decreased since the vaccination programme was implemented. Our analysis also indicated that human infections were closely related to poultry virus carriage rates; therefore, controlling FLUAV H7N9 circulation in poultry was an effective measure to control FLUAV H7N9 infections in humans. Although LBMs play a significant role in human infections, the management measures may not be implemented efficiently; hence, we need to conduct more investigations before developing related policies.The mechanistic modeling of preparative liquid chromatography is still a challenging task. Nonideal thermodynamic conditions may require activity coefficients for the mechanistic description of preparative chromatography. In this work, a chromatographic cation exchange step with a polypeptide having a complex elution behavior in low and high loading situations is modeled. Model calibration in the linear range of the isotherm is done by applying counterion-induced linear gradient elution experiments between pH 3.3 and 4.3. Inverse fitting with column loads up to 25 mg/mLCV is performed for parameter estimation in the nonlinear range. The polypeptide elution peak shows an anti-Langmuirian behavior with fronting under low loading conditions and a switch to a Langmuirian behavior with increasing load. This unusual elution behavior could be described with an extended version of the sigmoidal Self-Association isotherm including two activity coefficients for the polypeptide and counterion in solution. The activity coefficient of the solute polypeptide shows a strong influence on the model parameters and is crucial in the linear and nonlinear range of the isotherm. The modeling procedure results in a unique and robust model parameter set that is sufficient to describe the complex elution behavior and allows modeling over the full isotherm range.Drawing from conservation of resource theory and the social support resource theory, this study examines how the severity of an exogenous disruptive event - the COVID-19 pandemic - in one's community influences teleworkers' well-being outcomes indirectly through their perceptions of pandemic-related threat and experience of professional isolation, as well as the buffering effect of friendship on these relationships. Utilizing time-lagged data from participants of a two-wave survey panel (N = 351) and objective data of COVID-19 severity from counties around the United States, we found that perceived threat, but not professional isolation, mediated the negative effect of proportion of confirmed COVID-19 cases in the community on teleworkers' well-being outcomes. Further, consistent with our predictions, support from friends significantly weakened the negative effects of threat and professional isolation on well-being. Key theoretical and practical implications of this study are discussed.Circulating microRNAs (miRNAs) can be used as noninvasive biomarkers and are also found circulating in body fluids such as blood. Dysregulated miRNA expression is associated with many diseases, including non-small cell lung cancer (NSCLC), and the miRNA assay is helpful in cancer diagnosis, prognosis, and monitoring. In this work, a versatile electrochemical biosensing system is developed for miRNA detection by DNAzyme-cleavage cycling amplification and hybridization chain reaction (HCR) amplification. With cleavage by Mn2+ targeted DNAzyme, DNA-walker can move along the predesigned DNA tracks and contribute to the transduction and enhancement of signals. For the electrochemical process, the formation of multiple G-quadruplex-incorporated long double-stranded DNA (dsDNA/G-quadruplex) structures is triggered through HCR amplification. The introduction of G-quadruplex allows sensitive measurement of miRNA down to 5.68 fM with good specificity. Furthermore, by profiling miRNA in the NSCLC cohort, this designed strategy shows high efficiency (area under the curve (AUC) of 0.
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