Notes

COVID-19 recommender program determined by the annotated multilingual corpus.
The ready availability of sequential CT offers a valuable opportunity for body composition assessment, but the quality of assessment and interpretation must improve before the impact of body composition on treatment-related outcomes and survival can be assessed. We suggest recommendations for the assessment of body composition for the design of future studies.
The ready availability of sequential CT offers a valuable opportunity for body composition assessment, but the quality of assessment and interpretation must improve before the impact of body composition on treatment-related outcomes and survival can be assessed. We suggest recommendations for the assessment of body composition for the design of future studies.
Identifying the risk factors for falls among the elderly population is arguably one of the most imperative public health issues in the current aging society.

This study aimed to determine the associations between depressive symptoms, subjective cognitive decline (SCD), and poor subjective sleep quality and the risk of slips/falls in a Korean older population.

This cross-sectional study involved 228,340 elderly individuals living in Korea. Measurements included self-reported depressive symptoms, SCD, and self-reported sleep quality. The risk of slips/falls was dichotomized depending on whether slips/falls had occurred during the past year, and the associations between different risk factors and slips/falls were explored. Multiple logistic regression was used to obtain the odds ratios (ORs) and 95% confidence intervals (CIs). Complex sampling methods were used to estimate the weighted value of each participant.

The risk of slips/falls was significantly associated with high levels of depressive symptoms ve decline early and to improve sleep quality can be an alternative strategy to decrease the likelihood of falls.
The combination of acute myocardial infarction (AMI) and atrial fibrillation (AF) is still a thorny problem in the clinic. At present, there are few reports on the role of soluble suppression of tumorigenicity 2 (sST2) in AF after AMI. This study was to explore the predictive value of sST2 in patients with AMI for new-onset AF.

This is a single-center retrospective clinical observation study. We continuously included AMI patients from September 2019 to November 2021. The concentration of sST2 in blood samples was determined. During admission, a suspicious heart rhythm was recorded by electrocardiogram (ECG) monitoring, and new-onset AF was confirmed by immediate body surface ECG.

After multiple factors were included, age, right coronary artery, high-sensitivity C-reactive protein, left ventricular ejection fraction, and sST2 were still risk factors for new-onset AF. The area under curve value of age and sST2 was more than 0.7, which showed good diagnostic value. For reevaluation, the sST2 was added to the clinical new-onset AF prediction model. It was found that the integrated discrimination improvement and net reclassification index in the model were improved significantly.

sST2 is an independent predictor of new-onset AF in patients with AMI and can improve the accuracy of the AF risk model.
sST2 is an independent predictor of new-onset AF in patients with AMI and can improve the accuracy of the AF risk model.In this study, the biochar obtained from waste cotton fibers was introduced into the Ag-doped g-C3N4/TiO2 hybrid composite through a facile one-step hydrothermal process. The morphology, elemental composition, crystal structure, microstructure, specific surface area, chemical bonding state, energy band structure, and separation efficiency of photoinduced charge carriers of the resultant composite were examined using scanning electron microscope, energy dispersive X-ray spectrometer, X-ray diffractometer, transmission electron microscope, surface area analyzer, X-ray photoelectron spectroscope, Ultraviolet-visible spectrophotometer, ultraviolet photoelectron spectroscope, and photoluminescence spectroscope. The adsorption isotherms, kinetics and thermodynamics of the biochar, Ag-doped g-C3N4/TiO2 and Ag-doped biochar/g-C3N4/TiO2 were evaluated using the model methyl orange dye. The photoacatalytic degradation of the model pollutants including methyl orange, methylene blue, congo red, and tetracycline hydrochlo endothermic reaction with entropy reduction effects. As such, the Ag-doped biochar/g-C3N4/TiO2 exhibited a promising application for the treatment of wastewater containing multi-pollutants especially organic dyes and heavy metal ions.
Uncontrolled overproduction of inflammatory mediators is predominantly observed in patients with severe COVID-19. The excessive immune response gives rise to multiple organ dysfunction. Implementing extracorporeal therapies may be useful in omitting inflammatory mediators and supporting different organ systems. We aimed to investigate the effectiveness of hemoperfusion in combination with standard therapy in critically ill COVID-19 patients.

We conducted a single-center, matched control retrospective study on patients with confirmed SARS-CoV-2 infection. Patients were treated with hemoperfusion in combination with standard therapy (hemoperfusion group) or standard treatment (matched group). Hemoperfusion or hemoperfusion and continuous renal replacement therapies were initiated in the hemoperfusion group. The patients in the matched group were matched one by one with the hemoperfusion group for age, sex, oxygen saturation (SPO2) at the admission, and the frequency of using invasive mechanical ventilation , based on our study, the use of hemoperfusion may reduce the mortality rate and improve SPO2 and PaCO2.
Metabolic Syndrome (MetS) represents a common dysmetabolic state in children with obesity. Although data in youth show a role of gut hormones (GH) in the risk of developing MetS, no data are available during the prepubertal age, especially across clusters of MetS.

We characterized components of MetS and changes in GH concentrations in 90 prepubertal children with obesity compared to 30 healthy age- and gender-matched peers. Children with obesity were divided into three groups according to the number of the components of MetS (group 1 30 obese without components of MetS; group 2 30 obese with 1 component of MetS; group 3 30 obese with 2 or more components of MetS). Anthropometric parameters, blood pressure (BP), fasting insulin and glycemia, lipid profile, transaminases, and GH concentration were determined. Differences across the groups were evaluated by the Kruskal-Wallis test and post hoc analysis by Mann-Whitney test.

Fasting glycemia and insulin, HOMA-IR, triglycerides, and BP progressively increased and high-density lipoprotein progressively decreased across the groups of children with obesity compared to controls, showing worse values in group 3. GLP-1 and ghrelin values progressively decreased and obestatin progressively increased. The more components of the MetS were present, the further GH concentrations deviated from standard values.

Components of MetS and GH concentrations are impaired in prepubertal children with obesity compared to controls. The close association between progressive alterations in GH levels and increasing number of components of the MetS might indicate a role of these hormones in the determination of metabolic risk.
Components of MetS and GH concentrations are impaired in prepubertal children with obesity compared to controls. The close association between progressive alterations in GH levels and increasing number of components of the MetS might indicate a role of these hormones in the determination of metabolic risk.Extramedullary relapse of acute myeloid leukemia (AML) is not a rare event, and the FMS-like tyrosine kinase 3 (FLT3) mutation is a well-known risk factor. see more Gilteritinib is approved for relapsed/refractory FLT3+ AML, but its efficacy in extramedullary relapse is still undefined. Here, we present the case of a 69-year-old woman with therapy-related nucleophosmin-1 and FLT3-internal tandem duplication (FLT3-ITD) positive AML treated with induction and consolidation with CPX-351 (liposomal daunorubicin plus cytarabine) followed by off-label azacitidine maintenance who obtained a complete remission (CR) with persistent measurable residual disease. After 19 months of CR, she experienced an isolated breast relapse of FLT3-ITD+ AML. She was started on single-agent gilteritinib, resulting in a rapid and persistent complete regression of the breast nodule. Targeted therapy with gilteritinib for relapsed/refractory FLT3-ITD+ AML can be effective in isolated extramedullary relapse.In this study, we have investigated the effect of thickness on the structural and optical properties of copper (Cu) helical nanostructures. Thin films with thicknesses of 160 nm, 280 nm, 450 nm, and 780 nm were obtained by e-beam glancing angle deposition. The morphology and the microstructure were studied by field emission scanning electron microscopy, x-ray diffraction and transmission electron microscopy, while for the optical analysis measurements spectroscopic ellipsometry was used. The results show that the deposited structures are porous with nanometer-sized crystallites preferentially oriented along (111) planes, as well as that the diameter of the helices increases with thickness. Detailed analyses of optical properties have demonstrated that the dielectric function of Cu structures is greatly influenced by the films thicknesses. With increasing thickness from 160 nm to 780 nm, the surface plasmon resonance peak was shifted from 1.31 eV to 1.05 eV, which was correlated with the growth mechanism and the size of deposited nanostructures.Synapse devices are essential for the hardware implementation of neuromorphic computing systems. However, it is difficult to realize ideal synapse devices because of issues such as nonlinear conductance change (linearity) and a small number of conductance states (dynamic range). In this study, the correlation between the linearity and dynamic range was investigated. Consequently, we found a trade-off relationship between the linearity and dynamic range and proposed a novel training method to overcome this trade-off.Semiconductor photocatalysis has gained considerable attention in recent years due to their enabling nature to convert solar energy into fuels of renewable hydrocarbon. However, many of them suffer from some drawbacks like the inability to visible light irradiation and wide band gaps. Herein, we have synthesized monophasic strontium (Sr) doped SnO2nanoparticles by a cost-effective and environmental friendly hydrothermal method. As-synthesized nanoparticles showed rutile crystalline structure with irregular and rough cubical shape and no other elemental impurities. Sr-doped SnO2nanoparticles show a constant decrease in bandgap with increasing dopant concentration, which is estimated for excellent photocatalytic activity. The photocatalytic water splitting of as-prepared Sr-doped SnO2nanoparticles for H2generation shows a large influence of the increasing dopant concentration related to the narrowing bandgap on H2generation rate. Hence, the tunable bandgap with adjusted dopant concentration indicates that band gap tuning through doping for produced nanostructures may open up a new opportunities for photocatalytic and other optoelectronic applications.
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