Notes

COVID-19 Mandatory Vaccine regarding Medical Personnel as well as the French Make-up.
Solar steam generation based on the light-to-heat conversion via photothermal materials has been considered as one of emerged technologies for utilizing solar energy to produce clean water. Here, a hydrophobic PVDF/WS2 porous membrane for highly efficient solar steam generation was prepared by a scalable and low-cost method. The WS2 photothermal materials were fabricated through a simple ball milling, and then a non-solvent induced phase inversion method was used to fabricate the porous PVDF/WS2 membrane. The PVDF/WS2 evaporator could absorb the sunlight of 90.58% from UV to NIR region due to the multiscattering of the porous structure and the synergistic effect of WS2 and seawater. Moreover, the PVDF/WS2 evaporator exhibits the hydrophobic properties. check details Taking the advantages mentioned above, our evaporator could manifest the evaporation rate of 4.15 kgm-2h-1 with the solar thermal efficiency of 94.2% under 3 sun irradiation, as well as an outstanding durability upon continuous running. Also, the evaporator shows both the excellent seawater desalination and sewage treatment ability. Outdoor experiments illustrate that the evaporator has practical applications under a natural sunlight condition. link2 The numerous advantages of our PVDF/WS2 evaporator, including the high solar-thermal efficiency, the outstanding durability, and the simple and scalable manufacture process, may provide a potential photothermal material for the commercial solar desalination application and wastewater treatment.It is crucial to develop more effective photocatalysts in the field of clean environment. In response, the S-scheme BiVO4/g-C3N4 heterojunction modified by in situ reduced non-noble metal Bi nanoparticles was used to synergistically degrade formaldehyde under full spectral irradiation. The results, that investigated by careful characterizations and density functional theory (DFT) calculations, proved that BiVO4/g-C3N4 form an S-scheme heterojunction, which can effectively improve the separation efficiency of photogenic carriers and maintain the original strong redox capability of semiconductor materials. The SPR effect of Bi elemental substance enhanced the optical response and provided more oxidative species. Thus, the photocatalytic activity of BiVO4/Bi/g-C3N4 was significantly improved through their joint efforts, that the degradation efficiency of HCHO (800 ppm) for 6 h is 96.39% under 300 W Xenon lamp without filter with the pseudo-second-order rate constant of 4.16 ppm-1·h-1 and CO2 selectivity of 98.41%. Surprisingly, the degradation efficiency also reached to 49.35% and 32.23% under visible and near-infrared light irradiation, respectively. Moreover, we also tested its photocatalytic decomposition effect on formaldehyde in coatings, indicating that it has a broad prospect in future coatings applications. This study may provide an expected photocatalyst, an efficient non-noble metal modified S-scheme heterojunction, to degrade volatile organic gases under a broad spectrum light.This work presents the successful fabrication of a composite made of multi-walled carbon nanotubes and reduced graphene oxide, with immobilized zinc ferrite nanoparticles (ZnFe2O4@CNT/RGO). Functionalized CNT (F-CNT) and few-layered graphene oxide (GO) not only works as a precursor for the hierarchical CNT/RGO skeleton, but also participates in the redox reactions with zinc and ferrous ions to synthesize the intermediate products ZnO@CNT and FeOOH@RGO, respectively. A ZnO@CNT/FeOOH@RGO composite is obtained by through the spontaneous assembly process between the above intermediate species, and the final ZnFe2O4@CNT/RGO composite is fabricated through a simple solid-state reaction. The ZnFe2O4@CNT/RGO composite delivers a reversible capacity of about 1250 mAh·g-1 after 100 cycles at a low current of 200 mA·g-1, about 1100 mAh·g-1 after 300 cycles at a high current of 1000 mA·g-1. It has been verified that an increase in battery performance can be attributed to the engineered hierarchical CNT/RGO supportive skeleton, the generation of smaller electrochemically active ZnO and Fe2O3 crystals, and pseudocapacitive behavior. The sample design and preparation method in this work are both economical and scalable, allowing further development and use in other applications.In recent years, developing excellent electromagnetic wave (EMW) absorbers with small thickness and large bandwidth is an effective strategy to deal with the seriously EMW interferes in military and civil field. The morphology of absorbers has profound effects on their EMW absorption performance. Herein, ethylenediamine (EDA) was applied to EMW absorbing field as morphology control agent for the first time (as far as we know) for the synthesis of nickel cobaltate (NiCo2O4) absorber, and the effect of EDA content on the morphology and EMW absorbing performance was also investigated elaborately. As a bidentate ligand and structure-directing reagent, EDA controlled the morphology of NiCo2O4 by reducing the rate of nucleation and crystal growth through the complexation with metal ions, and adjusting the growth rate of different facets through the selective binding of amino to certain surfaces. The study found that the morphology of NiCo2O4 changed from three-dimensional urchin-like structures to two-dimensional nanosheets with the increase of EDA content, and meanwhile the dielectric loss property decreased, which led to decline in EMW attenuation properties. The urchin-like NiCo2O4 absorber at a molar ratio of 0.5 (EDA metal ions) exhibited optimum absorption properties with a small thickness of 1.70 mm and large effective absorption bandwidth (EAB) of 5.81 GHz (12.19-18 GHz). The excellent EMW absorbing properties mainly originate from remarkable dipole polarization induced by oxygen vacancies and lattice defects, interface polarization stemming from the interfaces of NiCo2O4 fibers, and multiple reflections and scattering in its unique urchin-like structures. This work provides a simple method for absorber with controlled morphologies, and also expands the family members of Co-based ferrite with outstanding absorbing performance.
While tailoring the pore diameters in hydrogel foams has been demonstrated in numerous studies, fine control over the diameters of the pore openings is still a challenge. We hypothesise that this can be achieved by controlling the size of the thin films which separate the bubbles in the liquid foam template. If this is the case, systematic changes of the template's gas fraction ϕ (the higher ϕ, the larger are the thin films) will lead to corresponding changes of the pore opening diameter.

Since the size of the thin films depends on both bubble size 〈D
〉 and gas fraction ϕ, we need to decouple both parameters to control the film size. Thus, we generated foams with constant bubble sizes via microfluidics and adjusted the gas fractions via two different techniques. The foams were solidified using UV light. Subsequently, they were analysed with confocal fluorescence microscopy.

We were able to change the pore opening diameter 〈d
〉 at a constant pore diameter 〈D
〉 by adjusting the gas fraction of the foam template. The obtained 〈d
〉/〈D
〉 ratios are between those obtained theoretically for disordered foams and FCC ordered foams, respectively.
We were able to change the pore opening diameter 〈dp〉 at a constant pore diameter 〈Dp〉 by adjusting the gas fraction of the foam template. The obtained 〈dp〉/〈Dp〉 ratios are between those obtained theoretically for disordered foams and FCC ordered foams, respectively.Radiotherapy is an effective method for treatment of a large proportion of human cancers. Yet, the efficacy of this method is precluded by the induction of radioresistance in tumor cells and the radiation-associated injury of normal cells surrounding the field of radiation. These restrictions necessitate the introduction of modalities for either radiosensitization of cancer cells or protection of normal cells against adverse effects of radiation. Non-coding RNAs (ncRNAs) have essential roles in the determination of radiosensitivity. Moreover, ncRNAs can modulate radiation-induced side effects in normal cells. Several microRNAs (miRNAs) such as miR-620, miR-21 and miR-96-5p confer radioresistance, while other miRNAs including miR-340/ 429 confer radiosensitivity. The expression levels of a number of miRNAs are associated with radiation-induced complications such as lung fibrosis or oral mucositis. The expression patterns of several long non-coding RNAs (lncRNAs) such as MALAT1, LINC00630, HOTAIR, UCA1 and TINCR are associated with response to radiotherapy. Taken together, lncRNAs and miRNAs contribute both in modulation of response of cancer cells to radiotherapy and in protection of normal cells from the associated side effects. The current review provides an overview of the roles of these transcripts in these aspects.
Accumulating evidence has demonstrated that microRNAs (miRNAs) are associated with tumorigenesis. miR-216b can play a vital role in the genesis and development of gastric cancer (GC), and its molecular mechanisms require further elucidation.

The biological effects of miR-216b in GC cells were investigated by MTT, transwell assays, and cell cycle. Western blot and luciferase assay were performed to demonstrate the direct binding of miR-216b on PXN 3'UTR. Furthermore, MTT, colony formation assays, transwell assays, and flow cytometry analysis, as well as xenograft mice model, were used to measure the effects of miR-216b-PXN on GC cell proliferation, migration, and invasion indicated by in vitro and in vivo.

Our results showed that miR-216b acted as a tumor suppressor in GC progression. miR-216b overexpression suppressed GC cell proliferation, migration, and invasion in vitro. link3 Luciferase reporter assays identified paxillin (PXN) as a novel target gene of miR-216b. PXN overexpression could partially rescue miR-216b-induced the inhibitory effects in GC cells. Besides, overexpression of miR-216b contributed to the activation of PI3K/AKT signaling via partly regulating PXN in GC cells.

The above results showed that miR-216b could offer a novel therapeutic avenue by targeting PXN in GC.
The above results showed that miR-216b could offer a novel therapeutic avenue by targeting PXN in GC.Gastric cancer is considered as the third leading cause of deaths and the fifth most common cancers worldwide. Common treatment approaches include chemotherapy, radiation, gastric resection and targeted therapies. The emergence of gastric cancer immunotherapy has already shown some promising results and have altered the therapeutic procedures. Now, different combination therapies as well as novel immunotherapies targeting new molecules have been proposed. Despite ongoing investigations on the therapeutic options and significant advancements in this regard, the disease is poorly prognosed. In fact, limited therapeutic options and delayed diagnosis lead to the progression, dissemination and metastasis of the disease. Current immunotherapies are mostly based on cytotoxic immunocytes, monoclonal antibodies and gene transferred vaccines. The use of Immune checkpoint inhibitors (ICIs) have grown rapidly. In this review, we aimed to explore perspective and progression of different approaches of immunotherapy in the treatment of GC and the clinical outcomes reported so far.
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