Notes

Bioavailability, Ingestion, along with Metabolism of Pelargonidin-Based Anthocyanins Making use of Sprague-Dawley Test subjects and Caco-2 Mobile or portable Monolayers.
This case report discusses Stress-induced Cardiomyopathy as a complication of CRS-HIPEC.Occupational trauma in carpentry is common in our society due to lack of awareness on occupational safety and poor availability and adherence towards protective equipment. Given below is an unusual case of a young carpenter who presented in the orthopaedic outpatient department with complaint of difficulty in walking for the last four days. On examination, restricted movement of the hip joint on extension was observed. On further work up in the form of radiological investigations, a long iron nail was discovered as incidental finding in the back in close proximity to the ascending colon and duodenum in the retroperitoneum. Elective laparotomy was performed to remove the nail, after which the patient improved clinically and his presenting complaints were completely resolved on further follow up. This demonstrates the unusual way in which such a case can present in the outpatient department instead of the emergency department and with symptoms that may prompt one to think of anything but foreign body trauma, emphasising the need for proper history and meticulous relevant clinical examination, as covert foreign body injury can occur to the back, especially in patients involved in such occupations.The following is a case report of a 17-day-old female baby, born at 35 weeks' gestation, weighing 2.6 kg. She was brought to us with reluctance to feed, swelling over the left side of her face and a fever documented at 102oF, along with an erythematous, tender, localised swelling over the left pre-auricular region that measured 2 x 1.5 cm in size. Diagnostic workup and ultrasound findings were consistent with parotitis; however, her blood culture was negative. The patient was managed on antibiotics but subsequently, developed a nosocomial infection while she was admitted in the hospital, which prolonged her hospital stay to a total of 16 days. Nevertheless, she had complete resolution of the signs and symptoms on her follow-up visit. Acute parotitis should be considered in the differential diagnosis of a neonate presenting with facial swelling, reluctance to feed or incessant crying. Lusutrombopag Timely and appropriate management can result in good recovery and minimising the potential for complications.Wheat pill (zinc or aluminium phosphide), also known as rice pill, is used as rodenticide in wheat and rice storage reservoirs. In developing countries such as Pakistan there has been an increase in the number of aluminium phosphide (wheat pill) poisoning with suicidal intent due to its easy accessibility. It has a high mortality rate, with no antidote available. A young female presented with classical signs and symptoms of wheat pill poisoning, although during her stay at the hospital she developed cardiac arrhythmias leading to shock, haematuria, pleural effusion, and hyperglycaemia due to acute pancreatitis. Due to the appropriate recognition and management of the complications, the patient was able to recuperate. Appropriate transfer to Intensive Care Unit and prompt recognition of complications can lead to good outcomes. We recommend that there should be a nationwide cognizance campaign regarding the lethal consequences of wheat pill consumption by humans and proper disposal of this deadly material.The current study evaluated the effect of virtual reality based balance training in 30 stroke patients recruited via purposive sampling technique for a clinical trial. Sealed envelope method was used to randomly allocate patients into two groups, i.e. Exer-gaming group (EGG) (n=15) and traditional training (TBT) group (n=15). Patients ranging in age from 50 to 60 years were included using Modified Rankin Scale (MRS). Patients with cognitive deficits, severe physical impairments, contractures, inability to perform tasks, complications of the joint that affected movement, history of recent fracture, arthritis and those on drugs that could affect their physical function were excluded. Data was collected using Berg Balance Scale (BBS) and Timed Up & Go Test (TUG). Significant improvement was observed in the exer-gaming training group after completing intervention (P less then 0.001). Exer-gaming appears to be more effective in improving functional level, mobility and balance in stroke patients. The study also suggests that exer-gaming further provides dynamic environment for stroke patients, thereby improving dynamic balance and mobility.The aim of this study was to evaluate the factors affecting intraoperative and postoperative complications in retrograde intrarenal surgery. In this retrospective cohort study, 706 retrograde intrarenal surgery procedures administered to 617 patients were reviewed. Intraoperative and postoperative complications were classified according to the modified Satava and modified Clavien classification systems. The stone-free rate was 407 (57.6%) and the success rate was 528 (74.8%). Intraoperative complications were observed in 215 (30.5%) patients. The most common intraoperative complication was mild bleeding 60(8.5%), while the only independent risk factor associated with intraoperative complications was the presence of residual stones. Postoperative complications were observed in 190 (26.9%) patients. The most common postoperative complication was fever requiring antipyretic drugs 60(8.6%), while independent risk factors associated with postoperative complications were the presence of residual stones and solitary kidney.This study was conducted on children between 2 and 10 years age to determine the frequency of hearing impairment in middle ear infection. It was a cross-sectional survey, done at Riphah International University from August 2018 to January 2019. Data was collected from the ENT Department of Children's Hospital Lahore through convenience sampling technique and included 52 patients with middle ear infection. Measurements for the level of hearing impairment were taken, and data was analysed using statistical package for social sciences, SPSS 20.0. Of the total 52 patients, 15 (28.8%) had ear infection once a month and 37 (71.2%) had it off and on. Mild hearing loss was determined in 35 (67.3%) patients,13 (25%) had moderate, 2 (3.8%) severe and 2 (3.8%) had normal hearing. It was concluded that most of the children with middle ear infections developed hearing loss.
Implantology is one of the most investigated topics in modern dentistry. The current review was planned to systematically summarise all industrial, mass production and experimental trends in dental implant manufacturing relative primarily to their surface modification conducted between January 2017 and January 2020.

The review was conducted in Army Medical College, National University of Medical Sciences, Rawalpindi, Armed Forces Institute Of Dentistry, Combined Military Hospital, Rawalpindi, Foundation University College of Dentistry, Fauji Foundation Hospital, Islamabad, and the Higher Education Commission Library, Islamabad. Literature was searched on PubMed, Scopus, Medline, Cochrane and Science Direct databases. The key words employed were "dental Implants", "surface modification", "surface morphology", "surface treatment" and "surface augmentation".

A total of 38 articles were short-listed and reviewed in detail. There was abundant evidence suggesting the importance of these surface modifications on improving the implant success. Several strategies have been suggested to modify the implant surface topography as well as surface chemistry in order to achieve a micro-porous structure with nano-scale architecture, with increased bio-activity; hydrophilicity and anti-bacterial properties.

There has been commendable success with many of these strategies in laboratories. However, following the success in ex-vivo studies, very few of these surface modalities have found their way to clinical set-ups.
There has been commendable success with many of these strategies in laboratories. However, following the success in ex-vivo studies, very few of these surface modalities have found their way to clinical set-ups.
To explain the success and failure of dental implant diameter on the efficiency of fatigue.

The systematic review was conducted using PubMed and Cochrane databases for Original Articles published in the English language from 1999 to 2019. Outcomes were evaluated to determine perceptions regarding the role of dental implant diameter in influencing the implant's fatigue performance. Data was analysed using SPSS 22.

Of the 263 abstracts retrieved, 53(20%) were reviewed. Of them, 14(26.4%) were included; 9(64.3%) systematic reviews, and 5(35.7%) studies. The implant diameter could be categorised into wide diameter (5-6mm), regular diameter (3.75-4mm), and small/narrow diameter (3-3.4mm). The narrow diameter implants are indicated through thin alveolar ridges and mesiodistal spaces (<7mm). The implants with narrow diameter would offer greater risk of fatigue failure for clinical situations with significant functional loading (p<0.05). No significant differences were found either in success or failure of dental implant diameter on fatigue efficiency at 1-year and 3-year follow-ups (p>0.05).

The technical complication of dental implant included abutment screw loosening or fracture, abutment and superstructure fracture, and implant body fracture. The review mainly focussed on the impact of dental implant diameter on the efficiency of fatigue and reviewed a significant impact of dental implant diameter on the fatigue efficiency.
The technical complication of dental implant included abutment screw loosening or fracture, abutment and superstructure fracture, and implant body fracture. The review mainly focussed on the impact of dental implant diameter on the efficiency of fatigue and reviewed a significant impact of dental implant diameter on the fatigue efficiency.Active learning strategies with innovative ways are used in the teaching and learning for the engagement of students in classroom settings. A number of studies talk about the benefits the students have shown while using the active learning methods in their science courses, like Biochemistry, Anatomy and Physiology, Microbiology and Pathophysiology. Active learning helps to retain material, motivate students and to develop thinking skills. In the science courses of nursing education, these are very much in use for developing critical thinking qualities. By applying active learning strategies in science courses of nursing education, one may clearly see how the students get engaged with the content. Some of these activities are interactive simulations, games, small group discussions, videos, blended learning, role-playing, pair share, flipped classroom, mini research projects, formative evaluations, quizzes, hands-on activities, etc.
To see the efficacy of rapid colour test for the sensitivity of ceftriaxone against clinical isolates of salmonella typhi.

The cross-sectional validation study was conducted at the Department of Microbiology, Pakistan Navy Ship Shifa Hospital, Karachi, from Nov 2018 to April 2019, and comprised clinical isolates of salmonella typhi that were obtained from five different hospitals in Karachi and Hyderabad. The isolates were tested using the rapid colour test. All the isolates were also tested using the conventional disc diffusion method and minimum inhibitory concentrations on the Vitek-2 version 8.01.

Of the 97 isolates, 83(85.5%) were ceftriaxone-resistant and 14(14.4%) were ceftriaxone-sensitive. Sensitivity and specificity of the rapid colour test were 100% when compared with the results of the other methods. All the results were readable within 2 hours on the colour test.

The colour test was found to be a rapid, accurate and inexpensive tool to screen for ceftriaxone resistance in typhoid-endemic areas.
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