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When UV-irradiation and Tween-80 were provided together, the former factor can provide the target sites for functional bacteria to colonize, and the later factor can provide more candidates waiting to colonize by stimulating proliferation. As a result, an even better proliferation and colonization result can be achieved through the synergistic effect between the two factors. To some extent, the exposure between potential degrading bacteria and substrates to be degraded can be increased, which will create conditions for degrading. Generally, this research can provide certain theoretical basis and technical guidance for the remediation of plastic-polluted soil and the ocean.Efficient high-concentration organics degradation (including 2-CP, phenol, and tetracycline) and simultaneous electricity generation were achieved via in situ producing H2O2 and synchronous catalytic conversion to more reactive oxygen species at stable modified copper foam cathode. The cathode was synthesized using the one-pot electrodeposition method and was used to in-situ generate H2O2 through the two-electron reduction of oxygen. The produced H2O2 was then catalytically converted into ·OH and ·O2- simultaneously. The results showed that the system using the Au-Fe co-modified cathode achieved an optimal rhodamine b (50 mg L-1) removal ratio and the removal ratios of 2-CP, phenol and tetracycline were all higher than 90% in 120 min. Meanwhile, it exhibited a high conversion performance of organics into electricity, which is superior to most of the reported PFC (Photocatalytic Fuel Cell) systems. Electron spin resonance test was conducted to ascertain the role of ·O2- and ·OH in the organics degradation. Furthermore, the Au-Fe-modified cathode exhibited superior stability for long-term application in the pH range of 3-7, which can be attributed to the protection of photocurrent and the interaction between Cu and Fe.Modeling high-resolution air pollution concentrations is essential to accurately assess exposure for population studies. The aim of this study is to establish an advanced exposure model to predict spatiotemporal changes in fine particulate matter (PM2.5), nitrogen dioxides (NO2), and ozone (O3) concentrations in Shanghai, China. The model is constructed on a geo-statistical modeling framework that incorporates a dimension reduction regression approach and a spatial smoothing function to deal with fine-scale exposure variations. We used a dataset with comprehensive observational and predictor variables that included monitoring data from both national and local agencies from 2013 to 2019, a high-resolution geographical dataset of predictor variables, and a full-coverage weekly satellite data of the aerosol optical depth at a 1 × 1 km2 resolution. Our model performed well in terms of the spatial and temporal prediction ability assessed by cross-validation (CV) for PM2.5 (spatial R2 = 0.89, temporal R2 = 0.91), NO2 (R2 = 0.49, 0.78), and O3 (R2 = 0.67, 0.81) at the national monitors over seven years according to the leave-one-out CV. For the predictions at the local agency monitoring stations, the overall CV R2 was between 0.77 and 0.89 across the air pollutants. We visualized the long-term and seasonal averaged predictions of the PM2.5, NO2, and O3 exposure on maps with a spatial resolution of 100 × 100 m2. Our study provides a useful tool to accurately estimate air pollution exposure with high spatial and temporal resolution at the urban scale. These model predictions will be useful to assess both short-term and long-term air pollution exposure for health studies.Technical chlorinated paraffins (CPs) are produced via radical chlorination of n-alkane feedstocks with different carbon chain-lengths (∼C10-C30). Short-chain CPs (SCCPs, C10-C13) are classified as persistent organic pollutants (POPs) under the Stockholm Convention. This regulation has induced a shift to use longer-chain CPs as substitutes. Consequently, medium-chain (MCCPs, C14-C17) and long-chain (LCCPs, C>17) CPs have become dominant homologues in recent environmental samples. However, no suitable LCCP-standard materials are available. Herein, we report on the chemical synthesis of single-chain C18-CP-materials, starting with a pure n-alkane and sulfuryl chloride (SO2Cl2). Fractionation of the crude product by normal-phase liquid-chromatography and pooling of suitable fractions yielded in four C18-CP-materials with different chlorination degrees (mCl,EA = 39-52%). In addition, polar side-products, tentatively identified as sulfite-, sulfate- and bis-sulfate-diesters, were separated from CPs. The new single-chain materials were characterized by LC-MS, 1H-NMR and EA. LC-MS provided Relative retention times for different C18-CP homologues and side-products. Mathematical deconvolution of full-scan mass spectra revealed the presence of chloroparaffins (57-93%) and chloroolefins (COs, 7-26%) in the four single-chain C18-CP-materials. Homologue distributions and chlorination degrees were deduced for CPs and COs. 1H-NMR revealed chemical shift ranges of mono-chlorinated (δ = 3.2-5.3 ppm) and non-chlorinated (δ = 1.0-3.2 ppm) hydrocarbon moieties. The synthesized C18-single-chain standard materials and respective spectroscopic data are useful to identify and quantify LCCPs in various materials and environmental samples. CP- and CO-distributions resemble the ones of existing SCCP and MCCP reference materials and technical mixtures. Furthermore, these materials now allow specific studies on the environmental fate and the transformation of long-chain chloroparaffins and chloroolefins.Environmental toxicity of antimony (Sb) is significantly increased through the widespread industrial application. The extended release of Sb above the regulatory level became a risk to humans habituated in the ecosystem. Conventional methods to remediate Sb demand high energy or resource input, which further leads to secondary pollution. The bio-electrochemical system offers a promising bioremediation strategy to remove or reduce toxic heavy metals. Thus, this research explores the possibilities of simultaneous metal sulfide (MeS) precipitation and electricity production using a full biological Microbial fuel cell (MFC). A non-conventional sulfate-reducing bacteria (SRB) Citrobacter freundii SR10 was used for this investigation, where the MFC was operated for lactate utilization in the bio-anode and Sb reduction at the bio-cathode. This study observed 81% of coulombic efficiency (bio-anode) and 97% of sulfate reduction with 99.3% Sb (V) reduction (bio-cathode), and it was concluded that the MeS precipitation entirely depends on sulfide concentration via SR10 sulfate reduction. The MFC-SR10 offers a maximum power density of 1652.9 ± 32.1 mW/m3, and their performance was depicted using cyclic voltammetry and electrochemical impedance spectroscopy. The Sb reduction was evaluated through fluorescence spectroscopy, and the Sb (V) MeS precipitation was confirmed as stibnite (Sb2S3) by Raman spectroscopy and X-ray photoelectron spectroscopy. Furthermore, the matured anodic and cathodic biofilm formation was confirmed by Scanning electron microscopy with Energy-dispersive X-ray spectroscopy. Thus the MFC with SRB bio-cathode can be used as an alternative to simultaneously remove sulfate and Sb from the wastewater with electricity production.Perfluorooctanoic acid (PFOA) is a persistent environmental pollutant and will continually accumulate in blood due to its chemical inertness and strong interaction with serum proteins, especially serum albumin (SA), inducing highly adverse health risks. However, the molecular mechanisms of dynamic interactions between PFOA with serum proteins remain unclear, limiting the development of potential therapeutic strategies. Herein, we developed an integrated structural strategy to systematically profile the molecular details of dynamic interactions among PFOA, SA, and β-cyclodextrin (β-CD) by combing native mass spectrometry (nMS), lysine reactivity profiling (LRP), and molecular docking (MD) simulation. The SA site 1, site 2 pockets, and cleft nearby are observed as the primary interaction regions of PFOA. Further, β-CD can disrupt the PFOA combinations with bovine SA regions around sites Lys20, Lys280, Lys350, and Lys431-Lys439, with an overall reversing efficiency of about 26% at an identical concentration to PFOA. The interactome of PFOA with complex human serum proteins is globally profiled with molecular interaction details, including human serum albumin, apolipoprotein A-I, alpha-2-macroglobulin, and complement C3. Our results reveal molecular insights into the detail of the interaction between PFOA and serum proteins, beneficial to understanding PFOA toxicology.People in the United States and around the world are widely exposed to pyrethroid pesticides. However, little is known about the effect of pyrethroids exposure on obesity in adults. This study examined the association between pyrethroids exposure and obesity in males and females and the role of obesity in the association of pyrethroids exposure with diabetes and cardiovascular disease (CVD). We used data from the National Health and Nutrition Examination Survey 1999-2002 and 2007-2014. Multivariate linear regression and logistic regression models were fitted to assess the association between urinary 3-Phenoxybenzoic Acid (3-PBA, a validated biomarker for pyrethroids exposure used in the primary analysis) and obesity. Mediation analyses were performed to investigate the mediation role of obesity on the associations of 3-PBA with diabetes and CVD. In this analysis, 7896 participants aged 20 years and above were included, of which 1235 (32.2%) males and 1623 (39.9%) females were diagnosed as obese. There was a significant interaction between sex and 3-PBA (Pinteraction = 0.004) for the risk of obesity. Among females, participants in the highest tertile of urinary 3-PBA had higher odds of obesity (OR = 1.22, 95% CI 1.00, 1.48) compared to those in the lowest tertile after adjusting for covariates. Among males, the association was not statistically significant. Similar trends were found in the associations of log-transformed urinary 3-PBA level with body mass index in males and females. Further, we found that, in males and females, obesity explained the effect of 3-PBA exposure on diabetes by 1.1% (P = 0.850) and 13.6% (P = 0.004), as well as cardiovascular diseases by 5.9% (P = 0.785) and 25.0% (P = 0.016), respectively. In conclusion, 3-PBA was significantly associated with a higher risk of obesity, especially in females. In addition, obesity partially mediated the associations of 3-PBA exposure with diabetes and CVD.Neonicotinoid insecticides can selectively interact with the unique nicotinic acetylcholine receptor subtypes in insects and are considered to be low toxic to mammals. However, there is still insufficient knowledge on human exposure to neonicotinoid insecticides, especially for children. this website This study aimed to investigate urinary concentrations and profiles of neonicotinoid insecticides in South China children and to analyze potential influencing factors. Six neonicotinoid insecticides, including imidacloprid (IMI), thiamethoxam (THM), acetamiprid (ACE), clothianidin (CLO), thiacloprid (THD) and dinotefuran (DIN), exhibited high detection frequencies (>90%) in urine samples collected from 305 children, suggesting broad exposure in South China children. The median concentrations were determined to be 0.13, 0.21, 0.01, 0.19, 0.002 and 1.64 μg/L, respectively. Among the target neonicotinoids, urinary concentrations of CLO and THM exhibited a significant and positive correlation between each other (p less then 0.05), suggesting similar sources of these two chemicals.
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