Notes

Record in the NIH Activity Power on Investigation Standards pertaining to Continual Mid back pain.
Cardiovascular effects of thyroid hormones may be measured through heart rate variability (HRV). We sought to determine the impact of hyperthyroidism on HRV.

A systematic review and meta-analysis on the impact of hyperthyroidism on HRV.

PubMed, Cochrane, Embase and Google Scholar were searched until 20 August 2021 for articles reporting HRV parameters in untreated hyperthyroidism and healthy controls. Random-effects meta-analysis was stratified by degree of hyperthyroidism for each HRV parameter RR intervals (or Normal-to-Normal intervals-NN), SDNN (standard deviation of RR intervals), RMSSD (square root of the mean difference of successive RR intervals), pNN50 (percentage of RR intervals with >50 ms of variation), total power (TP), LFnu (low-frequency normalized unit) and HFnu (high-frequency), VLF (very low-frequency), and LF/HF ratio.

We included 22 studies with 10,811 patients 1002 with hyperthyroidism and 9809 healthy controls. There was a decrease in RR (effect size = -4.63, 95% CI -5.7 to -3.56), SDNN (-6.07, -7.42 to -4.71), RMSSD (-1.52, -2.18 to -0.87), pNN50 (-1.36, -1.83 to -0.88), TP (-2.05, -2.87 to -1.24), HFnu (-3.51, -4.76 to -2.26), and VLF power (-2.65, -3.74 to -1.55), and an increase in LFnu (2.66, 1.55 to 3.78) and LF/HF ratio (1.75, 1.02 to 2.48) (
< 0.01). Most parameters had ES that was twice as high in overt compared to subclinical hyperthyroidism. Increased peripheral thyroid hormones and decreased TSH levels were associated with lower RR intervals.

Hyperthyroidism is associated with a decreased HRV, which may be explained by the deleterious effect of thyroid hormones and TSH. The increased sympathetic and decreased parasympathetic activity may have clinical implications.
Hyperthyroidism is associated with a decreased HRV, which may be explained by the deleterious effect of thyroid hormones and TSH. The increased sympathetic and decreased parasympathetic activity may have clinical implications.Previous research, that showed that corporate social responsibility (CSR) had positive effects on the corporate image and performance, has attracted much attention and resulted in an increasing number of follow-up studies. However, CSR-related activities are focused on their effect on external stakeholders, although they are social service activities geared towards internal and external stakeholders, thus showing a research gap regarding the effects of internal stakeholders on organizational effectiveness. Therefore, this study investigated the mediating effects of the value congruence climate and prosocial behavior among the team members in the relationship between leader's CSR perception and team members' psychological well-being, using a multilevel analysis of the relationship between the team and individual level factors. For the empirical analysis, 69 teams (334 employees) were sampled from 23 Korean small and medium-sized enterprises (SMEs). Analyses revealed a positive effect of a leader's CSR perception on the team members' psychological well-being. Furthermore, a leader's CSR perception had a positive effect on his/her team's value congruence environment and team members' prosocial behavior. The team's value congruence environment and team members' prosocial behavior were found to mediate the relationship between the leader's CSR perception and team members' psychological well-being. The relationships among these variables were investigated using a multilevel analysis model capable of simultaneous validation of team- and individual-level factors associated with team members' psychological well-being. Future research directions were then discussed based on the theoretical and practical implications and limitations of the study results.Breast cancer (BC) is globally the most frequent cancer in women. Adherence to endocrine therapy (ET) in hormone-receptor-positive BC patients is active and voluntary for the first five years after diagnosis. This study examines the impact of adherence to ET on 10-year excess mortality (EM) in patients diagnosed with Stages I to III BC (N = 2297). Since sample size is an issue for estimating age- and stage-specific survival indicators, we developed a method, ComSynSurData, for generating a large synthetic dataset (SynD) through probabilistic graphical modeling of the original cohort. We derived population-based survival indicators using a Bayesian relative survival model fitted to the SynD. Our modeling showed that hormone-receptor-positive BC patients diagnosed beyond 49 years of age at Stage I or beyond 59 years at Stage II do not have 10-year EM if they follow the prescribed ET regimen. This result calls for developing interventions to promote adherence to ET in patients with hormone receptor-positive BC and in turn improving cancer survival. The presented methodology here demonstrates the potential use of probabilistic graphical modeling for generating reliable synthetic datasets for validating population-based survival indicators when sample size is an issue.Adolescent internet gaming addiction (IGA) has become a serve public health problem, particularly in China. Despite the fact that the school climate has a significant impact on teenage IGA, little research has looked into the underlying mediating processes. This cross-sectional study looked at the impact of adolescents' perceptions of their school climate (including teacher-student support, student-student support, and opportunities for autonomy) on IGA in a sample of 1053 Chinese adolescents (Meanage = 13.52 years; 52.4% females) using convenient sampling methodology, as well as whether deviant peer affiliation mediated this association. Adolescents' school climate, IGA, and deviant peer affiliation were examined using the School Climate Questionnaire, Internet Gaming Addiction Scale, and two validated tools in this study. The results showed that teacher-student support and student-student support were both negatively associated with IGA, and that these correlations were mediated by deviant peer affiliation. The implications of these findings are discussed.The Cognitive Emotion Regulation Questionnaire (CERQ) is an assessment tool to evaluate cognitive emotion regulation strategies. The main objective of this study is to provide new empirical evidence about the validity and reliability of the CERQ via a sample of 271 Spanish adolescents (136 female, 135 male) aged from 15 to 18 years (M = 15.7, SD = 0.76). The analytical process was carried out in two phases. A confirmatory factor analysis was performed on the polychoric correlation matrix between items. Four possible alternative models were contrasted two models with nine factors and two models with two second-order factors and nine first-order factors, with 36 and 27 items, respectively. The model with nine correlated factors and 27 items obtained the best indices of overall fit. Subsequently, the reliability of the measurements was estimated on this model. The results reaffirm the validity of the 27-item version of the CERQ over the original 36-item structure. The findings also confirm that the CERQ is a reliable instrument for the evaluation of emotion regulation strategies in adolescents.People across the globe are facing increasingly complex public health emergencies that are responsible for the loss of life, economic and social problems with unprecedented damage and costs. For some sociologists, our society is even "a risk society" and our time is highly violative. Tyloxapol manufacturer Emergencies of different origin stemming from natural environmental disasters, such as floods, hurricanes, intense drought, technical accidents, social unrest and last but not least-outbreaks of infectious diseases. This decade started with one of the most significant pandemics in the history of man-kind-COVID-19. Hence, the problems of resilient health and healthcare systems have become urgent. Especially since SARS-CoV-2 may cause long-term health threats and recurrent crises. It is very important to have a common language. So far, definitions and concepts of health and healthcare resilience differ substantially and are seldom clearly defined. The aim of this paper is to describe how health and healthcare system resilience is defined to either uncover, recall, or in combination, its concept and prepare an introductory conceptual review as a preliminary step for further studies.This study aimed to (i) analyze fat mass and physical fitness variations among age-groups and playing positions, and (ii) explore the relationship between fat mass and physical fitness in youth male soccer players. A total of 66 players from under-16, under-17, and under-19 were tested. Body mass, skinfolds, countermovement jump (CMJ), single-leg triple hop jump (SLTH), bilateral triple hop jump (BTH), and yo-yo intermittent recovery Level 2 (YYIR-2) were assessed. A two- and one-way ANOVA were conducted, and the effect size was measured. Interactions were found in skin folds and fat mass. The under-19 group was taller, heavier, with a greater BMI and muscle mass than the under-16 group. They also exceeded the under-16 and under-17 in SLTH, BTH, and YYIRT-2. The under-17 group jumped higher and longer than under-16 group. Goalkeepers were taller and heavier than the midfielders. Central defenders were taller and had more muscle mass than midfielders and were heavier than the midfielders and wingers. The wingers jumped higher than the midfielders and showed better YYIRT-2. BMI was small correlated with YYIRT-2 and moderately with CMJ. Fat mass had a moderate negative correlation with CMJ and YYIRT-2. Muscle mass largely correlated with CMJ, UTH, very large with BTH and moderate with YYIRT-2. Summarily, with increasing age, better performances and body compositions were registered. Muscle mass better influences performance than body fat. Body composition can distinguish players positions.Hypothermia is an emergency caused by the lowering of the central body temperature with a slowdown of basic vital functions. Reduced mobility, old age, psychiatric or metabolic disorders are relevant risk factors. Diagnosis of death from hypothermia is a challenge, as there are no pathognomonic signs, and supportive findings can be inconstant. Wischnewsky Spots (WS) are blackish lesions of gastric mucosa, typically associated with hypothermic death. The pathophysiology of these lesions is still uncertain. The aim of this paper is to investigate the pathological mechanisms determining the appearance of WS by analyzing the current scientific knowledge in this area. We performed a narrative review of the literature published in the last 20 years, comparing the results with three cases of hypothermia reported from our experience. The review proved that WS show a multifactorial etiology, i.e., not only body temperature decrease, but also various extrinsic and intrinsic factors, such as physical and psychological stress, agony, causa mortis and metabolic comorbidities. The review summarizes the current knowledge in the field of incidence, pathology and morphology of WS by proposing some scientific and technical points for clinical and forensic analysis of this phenomenon.Less than 20% of cancer patients meet the recommended physical activity (PA) guidelines, partially due to poor knowledge and enforcement/encouragement amongst health-care professionals (HCPs). The primary aim of this study was to explore the perceptions of exercise practitioners on the role of PA and the physiological and psychological benefits to recovering cancer patients; the secondary aim was to understand the barriers and facilitators of promoting PA to cancer survivors. The third aim was to, seek the perspectives on the effectiveness of referral systems between the hospitals and PA structures. A purposive sample of five exercise practitioners' (four male and one female) with experience with cancer patients participated in a semi-structured interview (45-60 min). Interviews addressed five key topics intervention procedures, patient well-being, patient education on PA, effectiveness of referrals from hospitals, and post-intervention PA. Interviews were transcribed verbatim and analysed via thematic analysis.
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