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These two components interact such that knowledge of the world guides information sampling, and what is sampled updates knowledge. Like human decision makers, the model displays strategic sampling behavior, such as terminating information search when sufficient information has been sampled and adaptively adjusting the search path in response to previously sampled information. The model also shows human-like failure modes. For example, when information exploitation is prioritized over exploration, the bidirectional influences between information sampling and learning can lead to the development of beliefs that systematically differ from reality. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Genome-wide association (GWA) genetic epidemiology research has identified several variants modestly associated with brief self-report smoking measures, predominately in European Americans. E64d GWA research has not applied intensive laboratory-based measures of smoking endophenotypes in African Americans-a population with disproportionately low quit smoking rates and high tobacco-related disease risk. This genetic epidemiology study of non-Hispanic African Americans tested associations of 89 genetic variants identified in previous GWA research and exploratory GWAs with 24 laboratory-derived tobacco withdrawal endophenotypes. African American cigarette smokers (N = 528; ≥10 cig/day; 36.2% female) completed two counterbalanced visits following either 16-hr of tobacco deprivation or ad libitum smoking. At both visits, self-report and behavioral measures across six unique "sub-phenotype" domains within the tobacco withdrawal syndrome were assessed (Urge/Craving, Negative Affect, Low Positive Affect, Cognition, Hunger, and Motivation to Resume Smoking). Results of the candidate variant analysis found two significant small-magnitude associations. The rs11915747 alternate allele in the CAD2M gene region was associated with .09 larger deprivation-induced changes in reported impulsivity (0-4 scale). The rs2471711alternate allele in the AC097480.1/AC097480.2 gene region was associated with 0.26 lower deprivation-induced changes in confusion (0-4 scale). For both variants, associations were opposite in direction to previous research. Individual genetic variants may exert only weak influences on tobacco withdrawal in African Americans. Larger sample sizes of non-European ancestry individuals might be needed to investigate both known and novel loci that may be ancestry-specific. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Previous research suggests that parents' characteristics and race-related experiences shape the racial socialization messages they give their children. Parents' beliefs about race may also relate to how they interpret and respond to race-related stressors. The current study drew on the Sociohistorical Integrative Model for the Study of Stress in Black Families to examine the moderating roles of gender and racial identity subscales (i.e., racial centrality, private regard, and public regard) on the relations between race-related stressors (i.e., personal, vicarious, and anticipated racial discrimination) and racial socialization.

Path analyses were conducted in Mplus 8.2 using online survey data from a national sample of 567 African American parents of adolescents.

There were seven significant three-way interactions. Racial centrality and gender moderated the relations between both personal and vicarious racial discrimination and each racial socialization message. Private regard and gender moderated the essages African American parents who are exposed to race-related stressors give their children. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
To illuminate family implications of youth's work, we examined longitudinal links between the work experiences of Mexican-origin youth in late adolescence and young adulthood and father-youth relationships.

Using data from 187 Mexican-origin youth and their employed fathers, we tested youth's (52.4% female;

= 19.64,
= 1.78) work hours and workplace discrimination as predictors of paternal acceptance two years later (Time 1 paternal acceptance controlled), and tested moderation by youth gender and maternal employment.

Multivariate multilevel models revealed a curvilinear association between youth workplace discrimination and father-reported acceptance. Moderation effects of youth gender and mother employment in linear links between youth work experiences and youth-reported acceptance also emerged. Work hours were stronger negative predictors of paternal acceptance for sons than daughters and youth with employed compared to nonemployed mothers. Workplace discrimination was a positive predictor of paternal acceptance of daughters but not sons.

Findings highlight complex patterns in links between youth's work and family relationships, an understudied area. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Findings highlight complex patterns in links between youth's work and family relationships, an understudied area. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Although children's self-regulation has been widely regarded as a panacea, there may be individual differences in the adaptiveness of self-regulatory processes depending on temperamental factors. We examined whether individual differences in two conceptually distinct types of self-regulation (i.e., emotion self-regulation, nonemotion self-regulation) moderated the association between shyness measured during late childhood (N = 1284; 49.8% girls, 84.1% White, mean parental education fell between associate's degree/diploma and undergraduate degree) and prosocial tendencies indexed approximately two years later during early adolescence. We found that children's shyness was negatively associated with adolescents' prosocial tendencies only at high levels of emotion self-regulation, and that shyness was positively related to prosocial tendencies only at low levels of nonemotion self-regulation. In the context of relatively higher levels of shyness, being "over" emotionally regulated may interfere with positive socioemotional outcomes. These findings may provide additional insight into the heterogeneity of self-regulation, and why some shy children may be reluctant to engage in prosocial acts. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Objective Medication is particularly important to advocates within the mental health recovery movement and this movement is founded upon a resistance to coercive treatment. Given this history, we explored the perspectives of providers and service users engaged in the recovery-oriented practice Person-Centered Care Planning (PCCP) to understand (a). How providers trained in PCCP understand the role of psychiatric medication and (b). How service users receiving services from providers trained in PCCP understand and experience the role of psychiatric medication in treatment. Method This study comprises data from the qualitative phase of an NIMH-funded randomized trial of PCCP, an evidence-based recovery-oriented practice. Data were collected from 22 focus groups of providers and service users across seven community mental health centers. Interviews were analyzed using thematic analysis. Results Qualitative themes from the provider focus groups included "promoting adherence" and "medication as a precondition." Providers expressed that service users need to be adherent to medication and their symptoms managed before recovery-oriented practices could be pursued. Service user themes included "we were cattle" and medication as "my saving grace." While many experienced medication as helpful, they found providers' focus on adherence to be inflexible and, at times, coercive. Conclusion and Implications for Practice These results suggest that even within agencies actively implementing recovery-oriented practices, there are aspects of treatment, namely medication management, that are more impervious to recovery principles. Agency level trainings in PCCP and other recovery-oriented practices would benefit from the inclusion of all staff, including psychiatrists and other prescribers. (PsycInfo Database Record (c) 2021 APA, all rights reserved).A facile copper-catalyzed aminosulfonylation of O-homoallyl benzimidates with sodium sulfinates in the presence of tert-butyl peroxybenzoate (TBPB) and XPhos ligand has been developed. By using this protocol, a variety of potentially bioactive 1,3-oxazines were directly synthesized. This method has the merits of a cheap catalyst, easily available and stable sulfone reagents, and simple operation.Current treatment of chronic wounds has been critically limited by various factors, including bacterial infection, biofilm formation, impaired angiogenesis, and prolonged inflammation. Addressing these challenges, we developed a multifunctional wound dressing-based three-pronged approach for accelerating wound healing. The multifunctional wound dressing, composed of nanofibers, functional nanoparticles, natural biopolymers, and selected protein and peptide, can target multiple endogenous repair mechanisms and represents a promising alternative to current wound healing products.A new tandem annulation of p-quinone methides (p-QMs) with ynamides is described. This cascade reaction features a unique combination of (2 + 2) annulation, retro-4π electrocyclization, and imino-Nazarov cyclization, wherein vinyl p-quinone methides (p-VQMs) as one of the key intermediates have been identified chemically. Significantly, an unusual structural reconstruction of p-QMs involving the cleavage of the C5-C6 bond and the late-stage formation of the C4-C6 bond is involved, leading to a methodology development for the construction of functionalized aminoindenes.Lithium lanthanum titanate (LLTO) is one of the excellent candidates for an electrolyte in the all-solid-state Li-ion battery, owing to the high Li-ion conductivity in the bulk. However, the Li-ion conductivity at the grain boundary (GB) is largely reduced, and it is therefore important to reveal the origin of Li-ion conductivity reduction at the GB. Here, by using atomic-resolution scanning transmission electron microscopy combined with atomic force microscopy, we investigate the charge states, Li-ion conductivities, atomic and electronic structures at the LLTO Σ5 and Σ13 GBs. Although the Σ5 GB has no significant influence on Li-ion conductivity, the Σ13 GB shows the evident reduction of Li-ion conductivity. We further elucidate that the Σ13 GB is positively charged by the formation of oxygen vacancies at the GB. Such a positive charge would form the Li-ion depletion layers adjacent to the GB, which causes the significant reduction of Li-ion conductivity.The detection of polarization states of light is essential in photonic and optoelectronic devices. Currently, the polarimeters are usually constructed with the help of waveplates or a comprehensive metasurface, which will inevitably increase the fabrication complexity and unnecessary energy loss. Here, we have successfully demonstrated a self-powered filterless on-chip full-Stokes polarimeter based on a single-layer MoS2/few-layer MoS2 homojunction. Combining the built-in electric field enhanced circular photogalvanic effect with the intrinsic optical anisotropy of MoS2 between in-plane and out-of-plane directions, the device is able to conveniently sense four Stokes parameters of incident light at zero bias without requiring an extra filtering layer and can function in the wavelength range of 650-690 nm with acceptable average errors. Besides, this homojunction device is easy to integrate with silicon-based chips and could have much smaller sizes than metasurface based polarimeters. Our study thus provides an excellent paradigm for high-performance on-chip filterless polarimeters.
Website: https://www.selleckchem.com/products/Aloxistatin.html
     
 
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