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Usefulness along with Basic safety regarding Enteral Recombinant Human being Blood insulin with regard to Decrease in Time-to-Full Enteral Giving in Preterm Infants: The Randomized, Double-blind, Placebo-Controlled Demo.
Responding approximated vehicle levels for many drug doses tested, but at least half of the monkeys responded for ≥ one dose of each cannabinoid and heroin above vehicle, with the exception of THC. Drug deliveries calculated as percent vehicle followed a prototypical inverted-U shaped dose-response curve for cannabinoids and heroin except for THC and JWH-018 (in males). Grouped data according to sex demonstrated that peak percent of vehicle reinforcers earned for THC was greater in males than females, whereas peak percent of vehicle reinforcers earned for JWH-018, HU-210, and heroin were greater in females than males. These findings indicate minimal reinforcing effects of CB1 receptor agonists when self-administered by NHPs via aerosol inhalation. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Objectives Racial-ethnic minority youth face multiple types of victimization associated with negative developmental outcomes. The present study examined the interplay of youth experiences of online and offline bullying/harassment and racial-ethnic discrimination across three waves. Methods Racial-ethnic minority adolescents aged 10-19 (N = 735) at Midwest schools were surveyed yearly on Internet usage and experiences, mental well-being, and related risk and protective factors. We analyzed offline and online bullying/harassment, offline and online racial-ethnic discrimination, and time online in an autoregressive cross-lagged panel model. Results Youth who reported more of one type of victimization also reported more of other victimization types and more time online concurrently. Our results show some (but not consistent) influences over time. Youth who experienced more offline bullying/harassment at wave 1 were more likely to report more wave 2 victimization in another context (online bullying/harassment) and in other content (offline racial-ethnic discrimination), although these associations did not appear in the second wave. Youth who reported more online bullying/harassment at wave 2 also experienced increased risk for offline bullying/harassment at wave 3. Youth who reported more time online were not more likely to experience later victimization, though youth who experienced more wave 1 offline bullying/harassment were more likely to report more next-wave time online. Conclusions Racial-ethnic minority youth simultaneously and persistently face multiple types of victimization. Offline bullying/harassment interventions may have the added benefit of reducing other forms of victimization down the road, while reducing time online alone is unlikely to protect youth. (PsycInfo Database Record (c) 2021 APA, all rights reserved).The dual-basis theory of metamemory suggests that people evaluate their memory performance based on both processing experience during the memory process and their prior beliefs about overall memory ability. However, few studies have proposed a formal computational model to quantitatively characterize how processing experience and prior beliefs are integrated during metamemory monitoring. Here, we introduce a Bayesian inference model for metamemory (BIM) which provides a theoretical and computational framework for the metamemory monitoring process. BIM assumes that when people evaluate their memory performance, they integrate processing experience and prior beliefs via Bayesian inference. We show that BIM can be fitted to recall or recognition tasks with confidence ratings on either a continuous or discrete scale. Results from data simulation indicate that BIM can successfully recover a majority of generative parameter values, and demonstrate a systematic relationship between parameters in BIM and previous computational models of metacognition such as the stochastic detection and retrieval model (SDRM) and the meta-d' model. We also show examples of fitting BIM to empirical data sets from several experiments, which suggest that the predictions of BIM are consistent with previous studies on metamemory. In addition, when compared with SDRM, BIM could more parsimoniously account for the data of judgments of learning (JOLs) and memory performance from recall tasks. Finally, we discuss an extension of BIM which accounts for belief updating, and conclude with a discussion of how BIM may benefit metamemory research. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Describing, analyzing, and explaining patterns in eye movement behavior is crucial for understanding visual perception. Further, eye movements are increasingly used in informing cognitive process models. In this article, we start by reviewing basic characteristics and desiderata for models of eye movements. Specifically, we argue that there is a need for models combining spatial and temporal aspects of eye-tracking data (i.e., fixation durations and fixation locations), that formal models derived from concrete theoretical assumptions are needed to inform our empirical research, and custom statistical models are useful for detecting specific empirical phenomena that are to be explained by said theory. In this article, we develop a conceptual model of eye movements, or specifically, fixation durations and fixation locations, and from it derive a formal statistical model-meeting our goal of crafting a model useful in both the theoretical and empirical research cycle. https://www.selleckchem.com/products/ABT-888.html We demonstrate the use of the model on an example of infant natural scene viewing, to show that the model is able to explain different features of the eye movement data, and to showcase how to identify that the model needs to be adapted if it does not agree with the data. We conclude with discussion of potential future avenues for formal eye movement models. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Neurocognitive disorders in Parkinson's disease (PD) are common and heterogeneous. The aim of this study was to use a data-driven method to describe different cognitive phenotypes in PD and to explore anxiety, depression, and motor disturbances across the different cognitive profiles.

Latent profile analysis was applied to the neuropsychological performances of 65 patients with idiopathic PD assessed by means of a battery of tests that encompass measures of attention, memory, executive functions, social cognition, language, and visuospatial abilities.

A three-cluster model produced the best solution Cluster A (21.54%) included patients with intact cognition or with a relatively slight cognitive impairment in memory and executive functioning; Cluster B (53.85%) included patients with an intermediate level of cognitive impairment; and Cluster C (24.61%) included patients with the most severe cognitive impairment, with greater deficit compared to Cluster B in executive functioning, and, notably, in tasks w 2021 APA, all rights reserved).
In the Alzheimer's Disease Neuroimaging Initiative (ADNI), cognitive function was tracked across multiple years by a comprehensive neuropsychological battery. In this study, we examined the latent structure of the ADNI battery and evaluated the invariance of that structure among diagnostic groups and over time.

We used exploratory and confirmatory factor analyses to investigate the invariance of the ADNI battery's latent factor structure among three diagnostic groups (healthy controls, patients with mild cognitive impairment, patients with Alzheimer's disease) over a 2-year interval (baseline, 6 months, 12 months, 24 months).

The results revealed a five-factor structure for the ADNI battery (memory, visuospatial processing, attention, language, executive function). This structure displayed configural invariance but not weak, strong, or strict invariance across the three diagnostic groups. Longitudinally, configural, weak, strong, and strict invariance were all established within each diagnostic group, ed underlying factors remained invariant over 2 years, suggesting that this battery is a reliable tool for tracking longitudinal changes in specific cognitive abilities within individual diagnostic groups. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Neuropsychological instruments are often developed in English and translated to other languages to facilitate the clinical evaluation of diverse populations or to utilize in research environments. However, the psychometric equivalence of these assessments across language must be demonstrated before populations can validly be compared.

To test this equivalence, we applied measurement invariance procedures to a subsample (N = 1,708) of the Hispanic Community Health Survey/Study of Latinos (HCHS/SOL) across English and Spanish versions of a neurocognitive battery. Using cardinality matching, 854 English-speaking and 854 Spanish-speaking subsamples were matched on age, education, sex, immigration status (U.S. born, including territories, or foreign-born), and Hispanic/Latino heritage background. Neurocognitive measures included the Six-Item Screener (SIS), Brief-Spanish English Verbal Learning Test (B-SEVLT), Word Fluency (WF), and Digit Symbol Substitution (DSS). Confirmatory factor analysis was utilized to the underperformance of Spanish-speakers to some extent, more work is needed to determine whether such bias is reflective of true cognitive differences or additional variables unaccounted for in this study. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Prospective memory (PM), a salient component of neurocognitive functioning for people living with HIV (PLH), is necessary for planning and coordinating health-related behaviors and instrumental tasks of daily living. However, little is known regarding the impact of sociocultural factors on PM in diverse populations, particularly Latinx PLH. The aim of this study was to examine ethnic group differences and sociocultural factors related to PM.

The sample of 127 PLH (91 Latinx and 36 non-Latinx white) completed measures of quality of education, socioeconomic status (SES), and a validated PM measure, the Memory for Intentions Screening Test (MIST). The Latinx group also completed a bicultural acculturation measure.

Results revealed the Latinx and the non-Latinx white groups did not significantly differ in overall MIST performance (all p > .05). In the entire sample, better quality of education was associated with better MIST performance (all p < .05). Within the Latinx group, higher Latinx acculturatiord (c) 2021 APA, all rights reserved).
A deficit in interference control is commonly reported in children with attention deficit hyperactivity disorder (ADHD). This has mainly been interpreted as a difficulty in inhibiting inappropriate responses. However, it could be due to at least two distinct and independent processes, which are often confounded The activation or suppression of impulsive responses. The aim of the present study was to separate the contribution of these two processes.

We compared performance of 26 children with ADHD to that of 26 nonADHD children using a novel approach based on electromyographic activity (EMG) analysis. EMG allows two distinct indices to be computed Incorrect activation rate, which is an index of the intensity of impulse capture and correction rate, which provides a direct measure of the ability to suppress automatic responses.

Children with ADHD were slower, committed more errors, and had a larger interference effect than nonADHD children. Moreover, we observed a greater incorrect activation rate and a lower correction rate in the ADHD group.
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