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[Super steady capillary electrophoresis: idea and examples].
The purpose of this study is to develop a straightforward mathematical concept for determination of object to image magnification in both phakic and pseudophakic eyes, based on biometric measures, refractometry and data from an anterior segment optical coherence tomography (OCT).

We have developed a strategy for calculating ocular magnification based on axial length measurement, phakic anterior chamber and lens thickness, keratometry and crystalline lens front and back surface curvatures for the phakic eye, and axial length measurement, anterior chamber and lens thickness, keratometry and intraocular lens power, refractive index and shape factor for the pseudophakic eye. Comparing the magnification of both eyes of one individual yields aniseikonia, while comparing the preoperative and postoperative situation of one eye provides the gain or loss in ocular magnification. The applicability of this strategy is shown using a clinical example and a small case series in 78 eyes of 39 patients before and after canification does not change greatly after cataract surgery with implantation of an artificial lens, but in some cases, the change could be up to ±10%. If the changes are not consistent between the left and right eyes, then this could lead to post-cataract aniseikonia.Poor subsoil properties are difficult to ameliorate and detrimental to soil fertility and crop yield. The effects of loosening (L) and loosening + straw (LS) ∼60 Mg ha-1 into the subsoil (25-40 cm depth) on crop yield, water flow, and the nitrogen (N) balance components under bare soil conditions and a barley (Hordeum vulgare L.) crop were investigated in an about 21-mo lysimeter study and compared with a control treatment. Undisturbed soil columns (n = 12) were excavated from an agricultural field in May 2016, installed at a lysimeter station, and exposed to outdoor climatic conditions in Uppsala, Sweden, in August 2016. Spring barley ('Makof') was grown between June and September 2017. Total N leaching loads over the 21 mo were high (74-193 kg ha-1 ). The LS treatment reduced the N load by 49% (P = .01) and 62% (P = .001) compared with the L and control treatments, respectively. Loosening reduced N load by 25% (P .05), respectively. These results suggest that LS can reduce N leaching. The overall effects of LS on crop performance and N removal and leaching should be further scrutinized in long-term field studies.The nationwide lockdowns ended influenza seasons rapidly in Northern Hemisphere in Spring 2020. The strategy during the second wave was to minimize the restrictions set for children. Children spread influenza and therefore simultaneous influenza and COVID-19 surges were feared. The aim of this report is to analyze the epidemiology of influenza season 2020-2021 in Finland. Data for this retrospective register-based study were gathered from the National Infectious Disease Register, all laboratory-confirmed influenza cases from August 2017 to March 2021 were included. The positive influenza findings were stratified by age, and incidences per 100 000 persons were calculated. Only 41 influenza A and B cases have been reported in this season from August 2020 to March 2021, which adds up to an incidence of 0.9 per 100 000 person-years. In the three preceding years, the numbers and corresponding incidences from August to March were 12 461 (282 per 100 000 person-years) in 2019-2020, 15 276 (346 per 100 000 person-years) in 2018-2019, and 33 659 (761 per 100 000 person-years) in 2017-2018. Nonpharmaceutical interventions combined with the lockdown measures interrupted the influenza season in Finland in March 2020. Despite looser restrictions, alongside traveling restrictions and facial masks, failing to prevent the spread of the severe acute respiratory syndrome coronavirus 2 virus, these restrictions have proved to be effective against seasonal influenza.
To estimate the prevalence of computer vision syndrome (CVS) in presbyopic digital device workers using two ophthalmic progressive lens designs during the working day, and to analyse the association of CVS with sociodemographic, occupational, digital device exposure and refractive factors.

This time series, quasi-experimental design study included 69 presbyopic digital device workers (age range 46-69years; mean±SD=54.7±5.0). All used desktop computers at their workplace. Progressive addition lenses (PALs) and occupational lenses were used for three months each. CVS was measured with the CVS-Q
questionnaire before intervention (baseline) and at 1week, 1month and 3months after wearing the lenses. A multivariate logistic regression model was used to identify the factors that were associated with an improved CVS-Q
score.

37.7% of the subjects were female and 78.3% were ametropes; 65.2% had advanced presbyopia. 56.2% used digital devices at work >6hday
. The prevalence of CVS at baseline, after wearing PALs for three months and after three months of occupational lens wear was 68.1%, 33.3% and 18.8%, respectively. The mean CVS-Q
score was lower with occupational lenses than with PALs (p=0.001). 40.6% of the digital device workers improved their CVS-Q
score ≥2 points with the occupational lenses. Ametropes were less likely than emmetropes to improve with occupational lenses (OR=0.27, p=0.05). 89.8% of the sample workers were satisfied or very satisfied with the occupational lenses and 71% were similarly satisfied with the PALs. KRT-232 cell line 73.9% chose the occupational lenses as their first choice of lens for digital device use, compared with 17.4% for PALs.

Computer vision syndrome is reduced in presbyopic desktop computer workers wearing occupational lenses compared with PALs, especially in emmetropes.
Computer vision syndrome is reduced in presbyopic desktop computer workers wearing occupational lenses compared with PALs, especially in emmetropes.The kinetics of IgG antibodies after coronavirus disease 2019 (COVID-19) remain poorly understood. We investigated factors influencing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG antibody levels and time to seronegativation during the follow-up of severe and critically ill patients. We retrospectively reviewed serological evaluations drawn during the follow-up of severe or critical laboratory-proven COVID-19 patients hospitalized at a large academic hospital. Specific IgG titers were measured using a chemiluminescent assay targeting anti-spike and anti-nucleocapsid protein IgG. The influence of time, demographic factors, clinical and paraclinical characteristics, and COVID-19 therapeutics on IgG levels were assessed through linear regression using a mixed-effect model, and delay until IgG negativation through a Weibull regression model. The cohort included 116 patients with a total of 154 IgG measurements drawn at a median of 79 days after diagnosis. IgG antibodies were increased with age (p = 0.
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