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A selectivity-enhanced ratiometric fluorescence produced warning based on hand in glove aftereffect of covalent along with non-covalent acknowledgement models with regard to ultrasensitive recognition regarding ribavirin.
Competence-based approach plays an important role in the training of a modern doctor. Considering that the strategy of dental care for older age groups is determined not only by the demographic situation and its development, but also by the justified need for effective dental care, it is important to implement the teaching of gerontostomatology in a medical university based on the results of evidence-based medicine and a personalized approach. The aim of the work was to develop a methodology for teaching geriatric aspects according to the curriculum of a specialist in the discipline of maxillofacial surgery and surgical dentistry. Based on the study of scientific works on various aspects of gerontostomatology, the author's position is indicated in the work and methodological foundations for modern teaching of the gerontostomatology section are presented according to the curriculum of a specialist in the main areas of training in the field of maxillofacial surgery and surgical dentistry. Particular attention is paid to the methodology of teaching pyoinflammatory diseases and injuries of the maxillofacial region, salivology, pathology of the temporomandibular joint, masticatory muscles and oncostomatology.The assessment of barriers in persons older than working age with visual impairment was carried out using the International Classification of Functioning, Disabilities and Health to substantiate the list of necessary support services. An increase in the absolute number of people in older age groups objectively leads to an increase in the number of citizens experiencing difficulties in solving medical, social and psychological problems. Analysis of the results of the study showed that a significant part of people, due to impaired visual functions, experience limitations and barriers in physical environment, emotional sphere, family relationships with close and distant relatives. When assessing environmental barriers that interfere with the full-fledged life of persons with visual impairments, the presence of restrictions in sections D4 «Mobility», D5 «Self-service», D6 «Household life» was revealed. The presence of barriers and restrictions indicates the need to implement social protection measures, including rehabilitation, the need to adjust the list of support services. The use of the International Classification of Functioning, Disability and Health will determine the barriers faced by a disabled person due to visual impairment in various spheres of life and provide targeted assistance, support and assistance, to ensure the objectivity and sufficiency of social protection measures for each disabled person, on a scientific basis.The main task in the rehabilitation of athletes with traumatic injuries of the knee joint and surrounding soft tissues is effective and painless recovery at all stages of treatment. The aim of this work is to introduce a set of physical exercises for the treatment and prevention of traumatic injuries of the knee joint in middle-aged and elderly patients at the third stage of rehabilitation treatment (ICD-10 S80-S89). To date, there is no single regulated program for the management of middle-aged and elderly patients at the outpatient stage. The article describes the third stage of the organization of medical rehabilitation assistance in the late rehabilitation period, the period of residual symptoms of the course of the disease, without relapses. Physical exercises, presented in this complex, give the patient independence in everyday life in the implementation of self-service, independent movement, in the presence of the prospect of restoration of function (rehabilitation potential) confirmed by the results of the examination. The proposed technique was tested on 148 patients who underwent all 3 stages of rehabilitation treatment, in whom the duration of remission was 12-36 months.From 2017 to the present a scientific project «The use of dermatoprotectors to improve the quality of life of geriatric patients with age-associated xerosis (AAX)» has been realized as part of a typical model of a long-term care system in order to introduce the innovative gerontotechnologies as advanced social practices in further optimization of social and medical care for elderly and senile patients in Leningrad Region. The article presents the results of a comparative analysis of the effectiveness of the dermatoprotectors application in the improvement of the quality of life, prevention and correction of AAX. The AAX clinical manifestations have been studied before and after the emollients use. The cohort under study has included geriatric patients with senile asthenia from seven institutions of social protection of the Leningrad Region. In the foreign literature, such patients are called «fragile». The data thus obtained indicate that AAX as a manifestation of skin «fragility» during aging can be considered as a component of the geriatric syndrome of senile asthenia in patients of older age groups. The development of skin «fragility» significantly reduces the quality of life of geriatric patients and requires timely prevention and correction with adequately selected dermatoprotectors.The objective of this study was to identify the age-related peculiarities of the coordinated motor response and voluntary shift of the center of gravity (COG) in females aged 85-95. A total of 68 women within the age range of 85-95 were screened, mean age (М±SD) - 89,3±3. The first group comprised 37 women between the chronological ages of 85 and 89 (mean age 86,9±1,6). The second group included 31 women aged 90-95 (mean age 92,1±1,4). To achieve the stated objective the computer dynamic posturographic complex Smart Equitest Balance Manager (USA) was used. The following tests were conducted Motor Control Test (MCT), Rhythmic Weight Shift Test (RWS). The tests revealed a decreasing Composite of all Latencies (p=0,009) in the majority of the surveyed women aged 90-95. However, a comparative analysis of the RWS test results showed no statistically significant differences between the age groups. Cause and effect relationships between the RWS test results and subjective perception of aging were established. Women aged 90-95 demonstrated no decrease in the speed of the voluntary shift and effective control of COG in frontal and sagittal planes, whereas the latency of their coordinated motor response was marked by reliably low numbers compared to women aged 85-89. Thus, women after 89 experience no age-related alterations in sensorimotor integration, which could be regarded as a predictor of longevity. The results obtained made it possible to outline the MCT and RWS parameters which can be taken into consideration in forecasting postural alterations and life expectancy for older women.In the domestic and foreign specialized literature, there are no studies devoted to the study of risk factors of mortality in the older age patients with stroke-associated nosocomial pneumonia. The purpose of the study was to study the risk factors of adverse clinical outcomes in elderly and senile patients with stroke-associated nosocomial pneumonia. read more The study included 247 elderly and senile patients (139 men, 108 women, mean age -- 74,1±6,3 years) who were hospitalized with signs of ischemic or hemorrhagic stroke. According to the binary logistic regression model, the following parameters are statistically significantly associated with adverse clinical outcomes in the studied group of respondents age over 75 years (p=0.011), degree of disability according to mRS ≥3 (p=0,009), and C-reactive protein levels over 100 mg/l (p=0,023) and urea more than 7 mmol/l (p=0,044). In order to reduce the incidence of adverse clinical outcomes in patients of the older age group with stroke-associated nosocomial pneumonia, it is necessary to verify the above clinical and laboratory parameters at the early stages of hospitalization.At all stages of recovery after myocardial infarction (MI), the expansion of physical activity of elderly patients is one of the most important components. Of course, certain restrictions can reduce the load on the myocardium, reduce its oxygen needs and create conditions for early healing. Subsequently, depending on the dynamics and indicators of the cardiovascular system, the elderly patient is transferred from one stage of activity to another, the level of blood pressure, the number of heartbeats, the presence of arrhythmia, electrocardiogram data, EchoCG data, as well as individual load tolerance are evaluated. To date, there is a huge selection of optimal options for selecting methods of medical rehabilitation for elderly patients who have suffered a MI, and one of them is mechanotherapy. The mechanical therapy program of the David Back Concept complex - strength training is a set of simulators for working on the back muscles. The medical and diagnostic complex is designed for the diagnosis, treatment and prevention of pathologies of the musculoskeletal system, as well as for the rehabilitation of patients after surgical interventions and spinal injuries. Medical rehabilitation of elderly patients with coronary heart disease and after a MI through mechanotherapy, the program of the David Back Concept complex, provides for the restoration of their physical and social status to an optimally achievable level, determined by the capabilities of adaptive mechanisms.This study investigated elemental status in people from Republic of Karelia to identify gender- and age-related differences and deviations from standard values typical for the central part of Russia. We used hair samples taken from the head occipital zone to determine amounts of twenty-five chemical elements. Four-point scale that corresponds to deviation range and reflects the difference from hair macro- and microelement referent values was used. The inhabitants of Karelia tended to be excessive in toxic elements and extremely low in many essential macro- and microelements. Fifty-seven people over 60 years old were diagnosed with excess in toxic elements of Hg and Pb and deficiency in essential elements of Ca, Zn, Fe, and P. Age-related differences for Si, Na, and K were also found. The imbalance for Co, Mg, I, Cu, Fe, Cr, and Se was similarly typical for both older examinees aged over 60 and younger people of 20-25 years old participated as a baseline group for comparison. That indicates the need to prevent region-related microelementosis in all social groups regardless of age. Men were commonly low in Mg and Na while I, Zn, P, and Cr deficits were more common in women. Karelia residents' microelement imbalance proved to differ from standard values depending upon gender and age which requires a personalized approach to the mineral insufficiency treatment.The aim of the study was to evaluate the relationship between serum vitamin D deficiency and the risk of diastolic dysfunction in elderly patients with arterial hypertension. The study included 162 elderly patients (mean age 65,4±5,2 years) with arterial hypertension. The first group consisted of 67 patients with hypertension without vitamin D deficiency, the second-95 patients with hypertension with deficiency. It was revealed that the patients with vitamin D deficiency in the blood serum were significantly older (Δ7,3%, p less then 0,05), had a higher body mass index (Δ9,6%, p less then 0,05), a shorter distance in the 6-minute walk test (Δ10,4%, p less then 0,05), and more often (72,6%) had left ventricular diastolic dysfunction (LV DD). Patients with hypertension with LV DD in the presence of vitamin D deficiency in serum had a worse metabolic profile - they had higher values of total cholesterol (Δ15,7%, p less then 0,05), triglycerides (Δ15,2%, p less then 0,05), the НOMA-IR index (Δ12%, p less then 0,05) and lower HDL values (Δ11,9%, p less then 0,05).
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