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In silico analysis of deleterious SNPs of human being MTUS1 gene as well as their has an effect on about following proteins composition and function.
At the local scale, environmental parameters often require monitoring by means of affordable measuring techniques and technologies given they need to be frequently surveyed. selleck chemicals llc Streamflow in riverbeds or in channels is a hydrological variable that needs to be monitored in order to keep the runoff regimes under control and somehow forecast floods, allowing prevention of damage for people and infrastructure. Moreover, measuring such a variable is always extremely important for the knowledge of the environmental status of connected aquatic ecosystems. This paper presents a new approach to assessing hydrodynamic features related to a given channel by means of a beamforming technique that was applied to video sensing. Different features have been estimated, namely the flow velocity, the temperature, and the riverbed movements. The applied beamforming technique works on a modified sum and delay method, also using the Multiple Signal Classification algorithm (MUSIC), by acting as Synthetic Aperture Radar (SAR) post-processing. The results are very interesting, especially compared to the on-site measured data and encourage the use of affordable video sensors located along the channel or river course for monitoring purposes. The paper also illustrates the use of beamforming measurements to be calibrated by means of conventional techniques with more accurate data. Certainly, the results can be improved; however, they indicate some margins of improvements and updates. As metrics of assessment, a histogram of greyscale/pixels was adopted, taking into account the example of layers and curve plots. They show changes according to the locations where the supporting videos were obtained.The microseismic signal is easily affected by observation noise and the inaccurate estimation of traditional methods will seriously reduce the location accuracy of the microseismic event. Therefore, based on the continuous wavelet spectrum and the similarity coefficient, a fast and efficient microseismic time delay estimation method is proposed. Firstly, the original signals are denoised by continuous wavelet transform. Subsequently, the time-frequency transform of the original signal by continuous wavelet transform, time-frequency signal extraction is the process of band-pass filtering, which can further reduce the influence of noise interference on the time delay estimation. Finally, we calculated the similarity between the time-frequency signals via the time domain and frequency domain integration. The similarity function is based on correlation and proposed according to the time-frequency transformation provided by the phase spectrum to evaluate the similarity between two noisy signals. The time delay estimation is determined by searching for the similarity function peak. The experimental results show the precision and accuracy of the method over the cross-correlation method and generalized cross-correlation phase transformation method, especially when the signal-to-noise ratio is low. Therefore, a new time delay estimation method for non-stationary random signals is presented in this paper.Today, enterprises are multitasking, with branches set up all over the world. Virtual enterprises are created to make better use of existing resources, improve the quality of manufactured products and agilely respond to customer requirements. In order to fully meet the requirements of enterprises, a decentralized structure of data registration and transmission and authentication of network users is needed. The information collected via the Internet of Things and flowing based on the properties of the Blockchain (BC) network facilitates enterprise resource planning and enables the integration of internal processes, especially when planning, changing the current or introducing new production. The aim of this paper is to present the concept of using a common data register in BC technology, which enables a number of applications related to the automation of the process of selecting human resources for production tasks. The paper presents an analysis of the problem related to the integration of production scheduliresources planning.Deploying low maintenance and long-life systems is an important requirement of emerging commercial Internet of Things (IoT) solutions. Such systems can be envisioned in which the connected devices are powered by energy harvested from ambient sources and stored in long-lifetime capacitors rather than short-lived and polluting batteries. However, due to the unpredictable nature of ambient energy harvesting, such batteryless IoT devices might not always have enough energy to initiate communication. The Bluetooth Low Energy (BLE) specification defines support for Low Power Nodes (LPNs) using the friendship feature, where the LPN is associated with a neighbouring friend node (FN). The LPN can receive downlink (DL) data and remain connected to the network via the FN that buffers the LPN's incoming packets while allowing the LPN to save energy by sleeping or turning itself off. This novel BLE feature makes the LPN highly suitable to support the connection of batteryless ambiently-powered IoT devices. While the LPN can decide when to transmit uplink (UL) packets and does not depend on the FN to receive downlink (DL) data, the LPN needs to poll its FN to receive the buffered packets. However, the DL packet latency increases with this process due to the buffering time at the FN. Therefore, in this work, we present an analytical model to characterize the performance as a function of DL data latency and packet delivery ratio (PDR) of a batteryless LPN powered by different harvesting powers and capacitor sizes. This would help to optimally choose the correct configuration of the batteryless LPN for its network deployment. We also compare the analytical model and simulation results, showing consistency with an average error of 2.23% for DL data latency and 0.09% for the PDR.Current studies are focused on the correlation between characteristic features extracted from the laser speckle pattern of machined surfaces and 2D surface roughness parameters. Since milled surfaces are 3D in nature, 3D surface roughness parameters will provide a more accurate representation of the surface. Novelties of this work are (1) an inexpensive laser pointer, which was used for presentation and was used without any spatial filtering setup for producing the laser speckle pattern; (2) a correlation study, which was conducted between characteristic features extracted from the speckle pattern and 3D surface roughness; and (3) the influence of angle of illumination, lens aperture size (f-number) and shutter speed on the correlation. A highest coefficient of determination of 0.8955 was obtained for the correlation between the gray level co-occurrence matrix descriptor, namely energy, and 3D surface roughness parameter, namely ten-point height S10z, at an illumination angle of 45°, f-number of 16 and shutter speed of 1/100 s.Accurate and reliable stride length estimation modules play a significant role in Pedestrian Dead Reckoning (PDR) systems, but the accuracy of stride length calculation suffers from individual differences. This paper presents a stride length prediction strategy for PDR systems that can be adapted across individuals and broad walking velocity fields. It consists of a multi-gait division algorithm, which can divide a full stride into push-off, swing, heel-strike, and stance based on multi-axis IMU data. Additionally, based on the acquired gait phases, the correlation between multiple features of distinct gait phases and the stride length is analyzed, and multi regression models are merged to output the stride length value. In experimental tests, the gait segmentation algorithm provided gait phases division with the F-score of 0.811, 0.748, 0.805, and 0.819 for stance, push-off, swing, heel-strike, respectively, and IoU of 0.482, 0.69, 0.509 for push-off, swing, heel-strike, respectively. The root means square error (RMSE) of our proposed stride length estimation was 151.933, and the relative error for total distance in varying walking speed tests was less than 2%. The experimental results validated that our proposed gait phase segmentation algorithm can accurately recognize gait phases for individuals with wide walking speed ranges. With no need for parameter modification, the stride length method based on the fusion of multiple predictions from different gait phases can provide better accuracy than the estimations based on the full stride.This paper addresses the problem of automatic quality inspection in assembly processes by discussing the design of a computer vision system realized by means of a heterogeneous multiprocessor system-on-chip. Such an approach was applied to a real catalytic converter assembly process, to detect planar, translational, and rotational shifts of the flanges welded on the central body. The manufacturing line imposed tight time and room constraints. The image processing method and the features extraction algorithm, based on a specific geometrical model, are described and validated. The algorithm was developed to be highly modular, thus suitable to be implemented by adopting a hardware-software co-design strategy. The most timing consuming computational steps were identified and then implemented by dedicated hardware accelerators. The entire system was implemented on a Xilinx Zynq heterogeneous system-on-chip by using a hardware-software (HW-SW) co-design approach. The system is able to detect planar and rotational shifts of welded flanges, with respect to the ideal positions, with a maximum error lower than one millimeter and one sexagesimal degree, respectively. Remarkably, the proposed HW-SW approach achieves a 23× speed-up compared to the pure software solution running on the Zynq embedded processing system. Therefore, it allows an in-line automatic quality inspection to be performed without affecting the production time of the existing manufacturing process.The performance of deep neural networks and the low costs of computational hardware has made computer vision a popular choice in many robotic systems. An attractive feature of deep-learned methods is their ability to cope with appearance changes caused by day-night cycles and seasonal variations. However, deep learning of neural networks typically relies on large numbers of hand-annotated images, which requires significant effort for data collection and annotation. We present a method that allows autonomous, self-supervised training of a neural network in visual teach-and-repeat (VT&R) tasks, where a mobile robot has to traverse a previously taught path repeatedly. Our method is based on a fusion of two image registration schemes one based on a Siamese neural network and another on point-feature matching. As the robot traverses the taught paths, it uses the results of feature-based matching to train the neural network, which, in turn, provides coarse registration estimates to the feature matcher. We show that as the neural network gets trained, the accuracy and robustness of the navigation increases, making the robot capable of dealing with significant changes in the environment. This method can significantly reduce the data annotation efforts when designing new robotic systems or introducing robots into new environments. Moreover, the method provides annotated datasets that can be deployed in other navigation systems. To promote the reproducibility of the research presented herein, we provide our datasets, codes and trained models online.
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