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In this Letter, we propose a new (to the best of our knowledge), promising concept of a hybrid femtosecond (fs) laser processing method composed of single-point scanning and holographic light modulation fabrication for manufacturing a tunable-size microtrap chip. The hybrid method not only ensures key microfluidic device precision but also greatly improves the fabrication speed. By using a new asymmetry-bracket-shaped microtrap design with a mechanical strain stretching method, real-time size-tunable trapping is obtained, and a 100% particle trapping retention is realized, ignoring the flow fluctuation. Finally, the microtrap array is successfully applied to trap single yeast cells and hold them for $sim10;rm h$∼10h without escaping.A radio frequency magnetron co-sputtering technique exploiting GaTe and $rm Sb_2 rm Te_3$Sb2Te3 targets was used for the fabrication of Ga-Sb-Te thin films. Prepared layers cover broad region of chemical composition ($sim10.0 - 26.3,, rm at.$∼10.0-26.3at. % of Ga, $sim19.9 - 34.4,, rm at.$∼19.9-34.4at. % of Sb) while keeping Te content fairly constant (53.8-55.6 at. % of Te). Upon crystallization induced by annealing, large variations in electrical contrast were found, reaching a sheet resistance ratio of $R_rm annealed/R_rm as - deposited;sim2.2 times 10^ - 8$Rannealed/Ras-deposited∼2.2×10-8 for the $rm Ga_26.3rm Sb_19.9rm Te_53.8$Ga26.3Sb19.9Te53.8 layer. Phase transition from the amorphous to crystalline state further leads to huge changes of optical functions demonstrated by optical contrast values up to $|Delta n| + |Delta k| = 4.20$|Δn|+|Δk|=4.20 for $rm Ga_26.3rm Sb_19.9rm Te_53.8$Ga26.3Sb19.9Te53.8 composition.Brillouin imaging is an emerging optical elastography technique that is able to generate maps of the mechanical properties at microscale with great potential in biophysical and biomedical fields. A key parameter is its spatial resolution, which is usually identified with that of the confocal microscope coupled to the Brillouin interferometer. Conversely, here we demonstrate that the mean free path of acoustic phonons plays a major role in defining the resolution, especially for high numerical aperture confocal setups. Surprisingly, the resolution of elastography maps may even deteriorate when decreasing the scattering volume.In this Letter, we develop a novel technique, to the best of our knowledge, to increase the link span ($ L_s $Ls) of a rolling shutter (RS)-based optical camera communications (OCC) system by reducing the spatial bandwidth of the camera in the out-of-focus regions. Olaparib We demonstrate a 400 m line-of-sight RS-based OCC link, which is to date the longest $ L_s $Ls reported in these systems, and develop a detection method to extract the information out of the video frames, successfully. The proposed system relaxes the condition of a large surface area for the transmitter light source. Consequently, we show that at 400 m $ L_s $Ls and exposure times of 100-80 µs, a data rate of 450 bps is achieved successfully.We study the behavior of silicon microparticles in a 1064 nm Gaussian-beam optical tweezers, showing that this semiconductor can be used to perform different types of optical manipulation experiments. Depending on the focal position and the laser power used, the particles can present an oscillatory dynamics in the tweezers or can be stably 3D-trapped with a trap stiffness that allows the application of femtoNewton forces with accuracy. A new, to the best of our knowledge, interpretation based on the photoexcitation of electrons in the valence band is proposed to explain the oscillations, and the quantities associated with such dynamics (e.g., amplitude, period, etc.) were characterized as a function of relevant parameters to optical tweezers setups.A dispersed fringe sensor (DFS) is a promising approach for sensing the large-scale piston error for segmented mirror systems. In this Letter, a novel method, to the best of our knowledge, for piston sensing based on a digital dispersed fringe (DDF), which is generated by wavelength tuning, is introduced. By continuously changing the wavelength of light passing through the sensor, a collection of far-field spot arrays can be acquired, which are used to construct the DDF with steps of accumulation and stacking in sequence for each inter-segment region. A correlation-based method is applied to extract the encoded piston information from the DDF. The method greatly eases the demanding hardware requirement in traditional DFS and shows high efficiency for the reason that it could simultaneously measure all of the relative piston settings; in addition, it exhibits strong robustness to noise.In this work, TmYAG (Tm$rm Y_3rm Al_5rm O_12$Y3Al5O12) ceramic-derived multimaterial fiber was fabricated by using the molten core method, which has a high gain per unit length of 2.7 dB/cm at 1950 nm. To our knowledge, this is the highest gain per unit length at 2 µm band in similar TmYAG-derived multimaterial fibers. A distributed Bragg reflector (DBR) fiber laser was built based on a 10-cm-long as-drawn fiber. The achieved 1950 nm laser, which has a maximum output power of $sim240;rm mW$∼240mW and a slope efficiency of 16.5%, was pumped by a self-developed 1610 nm fiber laser. What is more, an all-fiber-integrated passively mode-locked fiber laser based on the 10-cm-long as-drawn fiber was realized. The mode-locked pulses operate at 1950 nm with duration of $sim380;rm ps$∼380ps, and the repetition rate is 26.45 MHz. The results described here indicate that the TmYAG ceramic-derived multimaterial fiber with high gain per unit length has promising applications in 2 µm all-fiber fiber lasers.Given the important role played by 2-hydroxybiaryls in organic, medicinal and materials chemistry, concise methods for the synthesis of this common motif are extremely valuable. In seeking to extend the lexicon of synthetic chemists in this regard, we have developed an expedient and general strategy for the ortho-arylation of phenols and naphthols using readily available boronic acids. Our methodology relies on in situ generation of a uniquely reactive Bi(V) arylating agent from a bench-stable Bi(III) precursor via telescoped B-to-Bi transmetallation and oxidation. By exploiting reactivity that is orthogonal to conventional metal-catalysed manifolds, diverse aryl and heteroaryl partners can be rapidly coupled to phenols and naphthols under mild conditions. Following arylation, high-yielding recovery of the Bi(III) precursor allows for its efficient re-use in subsequent reactions. Mechanistic interrogation of each key step of the methodology informs its practical application and provides fundamental insight into the underexploited reactivity of organobismuth compounds.
Homepage: https://www.selleckchem.com/products/AZD2281(Olaparib).html
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