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Several differences have been reported between male and female patients with stroke in clinical and sociodemographic features, treatment, and outcomes. Potential effects in the inpatient rehabilitation population are unclear.
To evaluate the differences between male and female patients in discharge functional status, length of stay, and discharge home after inpatient rehabilitation for stroke.
Retrospective, population-based cohort study.
Inpatient rehabilitation centers in Ontario, Canada.
Male (N=10,684) and female (N=9459) patients discharged from acute care between September 1, 2012 and August 31, 2017, with a diagnosis of stroke and subsequently admitted to inpatient rehabilitation.
Female sex.
Discharge Functional Independence Measure (FIM) score, length of stay, and discharge home.
Female patients had a lower functional status at discharge (mean FIM score 94.1 vs. 97.8, p < .001) and a lower proportion were discharged home (81.1% vs. 82.9%, p=.001). Female and male patients had similar rehabilitation length of stay (mean 31.8 vs. 31.7 days, p=.90). In the adjusted analyses, there was no difference in discharge functional status between male and female patients (FIM score β -.20 [95% confidence interval [CI] -0.64 to 0.25]). Female patients had a mean length of stay 2% shorter (0.98 [95% CI 0.96-0.99]) and a higher odds of discharge home (odds ratio [OR] 1.14 [95% CI 1.05-1.24]).
There were no clinically significant sex differences in outcomes after inpatient rehabilitation for stroke. Observed sex disparities in the general stroke population may not be directly applicable to individuals undergoing inpatient rehabilitation.
There were no clinically significant sex differences in outcomes after inpatient rehabilitation for stroke. Observed sex disparities in the general stroke population may not be directly applicable to individuals undergoing inpatient rehabilitation.Developing the ecological scientist mindset among underrepresented students in ecology fields (Bowser and Cid, this Forum) provides timely and compelling strategies to broaden inclusion in ecology and environmental biology. Chronic underrepresentation of minorities in ecology and environmental disciplines (EE) is a crisis that is surprising to many, and even more surprising that, for African-Americans, this underrepresentation is more severe compared to other STEM disciplines. It is beyond irony that a discipline that values diversity as a cornerstone of ecological practice continues to struggle to achieve diversity in the ranks of its practitioners.The Cambodian government is attempting to mobilise government, donor and private sector funding to implement a coordinated FMD vaccination program (FMDVP). A necessary first step is to convince the farmers of the benefits of participating in and potentially financially supporting this program. Information was collected from 300 farmers in order to estimate the on-farm benefits and costs of their participation in an FMDVP. Implementing a successful vaccination program is difficult, and farmers understand from previous experience that there may be institutional, social, technical and financial constraints which limit its success. A benefit-cost analysis needs to take into account that outbreaks do not occur every year, not all cattle will be successfully vaccinated, not all sick animals successfully treated and sometimes sick animals simply sold. This study sensitises these variables in order to give a realistic estimation of the farmer participation benefits in an FMDVP. A general result is that it is worthwhile for farmers to participate in the FMDVP if there are average annual outbreaks, or at least two major outbreaks, in the ensuing 5 years. However, the results are influenced by the interaction of vaccination success and treatment success and coverage. Ineffective coverage and poor treatment of sick animals reduce the benefits of an FMDVP. It is also important that farmers do not sell sick stock and, if they do, that they are able to breed replacements rather than purchase replacements. There are many factors in the smallholder cattle farming system that will influence the success of an FMDVP; farmers will only choose to participate if they can be convinced of the short and long-term economic benefits.Implicit motor sequence learning (IMSL) is a cognitive function that is known to be directly associated with impaired motor function in Parkinson's disease (PD). Research on healthy young participants shows the potential for transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, over the primary motor cortex (M1) to enhance IMSL. tDCS has direct effects on the underlying cortex, but also induces distant (basal ganglia) network effects-hence its potential value in PD, a prime model of basal ganglia dysfunction. To date, only null effects have been reported in persons with PD. However, these studies did not determine the reacquisition effects, although previous studies in healthy young adults suggest that tDCS specifically exerts its beneficial effects on IMSL on reacquisition rather than acquisition. In the current study, we will therefore establish possible reacquisition effects, which are of a particular interest, as long-term effects are vital for the successful functional rehabilitation of persons with PD. Using a sham-controlled, counterbalanced design, we will investigate the potential of tDCS delivered over M1 to enhance IMSL, as measured by the serial reaction time task, in persons with PD and a neurologically healthy age- and sex-matched control (HC) group. Multilevel Mixed Models will be implemented to analyze the sequence-specific aspect of IMSL (primary outcome) and general learning (secondary outcome). We will determine not only the immediate effects that may occur concurrently with the application of tDCS but also the short-term (5 min post-tDCS) and long-term (1 week post-tDCS) reacquisition effects.
Population-specific studies of vaccine uptake in pregnancy are necessary to monitor progress and ensure enablers to vaccination are locally relevant. PFK158 We aimed to determine the uptake of influenza and pertussis vaccine during pregnancy in women in south-east Queensland and the reasons why women were choosing not to vaccinate.
A secondary analysis of data collected in a prospective cohort study. Data were collected at enrolment during pregnancy and within six weeks of giving birth. The primary outcome was the proportion of women vaccinated during pregnancy.
Among 310 pregnant women, 45.8% and 69.7% were vaccinated against influenza and pertussis, respectively; 123 (39.7%) had received both vaccines. The common predictor of vaccine uptake for influenza, pertussis or both was having had any vaccine in the 12 months prior to pregnancy. Not considering the vaccines necessary and perceptions of the risk of infection were common reasons for not intending to vaccinate.
Antenatal vaccine uptake remains suboptimal in women in south-east Queensland. Barriers to vaccination during pregnancy are complex and vary depending on context and population. Implications for public health More efforts are needed to promote antenatal uptake, particularly for influenza vaccine and having both the influenza and pertussis vaccines during pregnancy.
Antenatal vaccine uptake remains suboptimal in women in south-east Queensland. Barriers to vaccination during pregnancy are complex and vary depending on context and population. Implications for public health More efforts are needed to promote antenatal uptake, particularly for influenza vaccine and having both the influenza and pertussis vaccines during pregnancy.How do students discover ecology? Answering this question is essential for diversifying the environmental workforce because scientific disciplines, such as ecology, are often not discovered until students enter academia and are exposed to different disciplinary options. Ecology, and many of the environmental sciences, have persistent and alarmingly low numbers of underrepresented minorities (URM; African American, Hispanic American, Native American, and Pacific Islanders), while other science and technology fields have shown progress in diversification. Why does such underrepresentation persist in environmental disciplines? Social factors such as sense of belonging, science identity, implicit biases, and stereotypes all have been explored and are known to influence the participation of URM students in science. The unique role of the field experience in environmental sciences as a "rite of passage" and "authentic" research experience is one important influence on how URM students experience ecology. Interventions using social elements such as belonging and sense of place are demonstrated ways to broaden participation particularly in environmental science fields, yet dramatic underrepresentation still persists. Here we review known factors affecting and enhancing the recruitment and retention of URMs in the sciences and focus on comprehensive strategies shown to be effective recruiting URM students into the environmental workforce.
An energetically demanding environment like a wilderness expedition can lead to potent stressors on human physiology and homeostatic balance causing shifts in energy expenditure and body composition. These shifts likely have consequences on overall health and performance and may potentially differ by sex. It is therefore critical to understand the potential differential body composition and energy expenditure changes in response to a novel and challenging environment in both males and female bodies.
Data were collected from 75 healthy individuals (female=41; ages 18-53) throughout a 3-month long expedition in the American Rockies. Body mass, body fat, and lean muscle mass were measured before, during, and after the course. Physical activity intensity and energy expenditure were also measured in a subset of participants using the wGT3X-BT Actigraph wrist monitor and an accompanying Bluetooth heart rate monitor.
Over the 3-month period, individuals initially experienced declines in body mass, body fat percentage, and lean muscle mass. Participants partially rebounded from these deficits to maintain overall body mass with a slight recomposition of body fat and lean muscle mass. Our data also demonstrated that sex moderated total energy expenditure, where females experienced a modest decline whereas males experienced an increase in energy expenditure from the beginning to the end of the course.
Understanding changes in energy storage in the body and variation in energy expenditure between sexes during a 3-month expedition has critical implications for maintaining health and performance in an energetically demanding environment where resources may be scarce.
Understanding changes in energy storage in the body and variation in energy expenditure between sexes during a 3-month expedition has critical implications for maintaining health and performance in an energetically demanding environment where resources may be scarce.Intellectual diversity, which is often assessed through social diversity proxies, such as race, ethnicity, and gender, is essential to innovation in ecology. There are many diverse ways of knowing, valuing, and discerning alternatives within ecology and as it is applied to solve global-change issues. However, science is a cultural activity, one that is affected by colonialism, racism, and White supremacy and, like other fields of science, the pursuit of ecological careers has historically been a space of limited opportunities for participation for Black, Indigenous, and People of Color (BIPOC)-narrowing the diverse ways of knowing, valuing, and engaging in ecological work. We seek to debunk the view that such limited participation is a result of BIPOC lacking interest in or proficiency in science, and instead offer that BIPOC communities are places of deep scientific understanding, sociocultural resilience, and cultural wealth. Scientists must broaden their consideration of the ecological sciences and work with BIPOC to establish community-based scientific partnerships that will foster increased ecological career pathways for BIPOC youth.
Website: https://www.selleckchem.com/products/pfk158.html
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