Notes
Notes - notes.io |
Our model can be embedded in any general CNN to form a video-level attention network for action recognition. Experimental results show that our method achieves state-of-the-art results on the datasets UCF101, HMDB51, Kinetics-400, and untrimmed Charades.Spherical images or videos, as typical non-Euclidean data, are usually stored in the form of 2D panoramas obtained through an equirectangular projection, which is neither equal area nor conformal. The distortion caused by the projection limits the performance of vanilla Deep Neural Networks (DNNs) designed for traditional Euclidean data. In this paper, we design a novel Spherical Deep Neural Network (DNN) to deal with the distortion caused by the equirectangular projection. Specifically, we customize a set of components, including a spherical convolution, a spherical pooling, a spherical ConvLSTM cell and a spherical MSE loss, as the replacements of their counterparts in vanilla DNNs for spherical data. The core idea is to change the identical behavior of the conventional operations in vanilla DNNs across different feature patches so that they will be adjusted to the distortion caused by the variance of sampling rate among different feature patches. We demonstrate the effectiveness of our Spherical DNNs for saliency detection and gaze estimation in 360° videos. To facilitate the study of the 360 video saliency detection, we further construct a large-scale 360° video saliency detection dataset. Comprehensive experiments validate the effectiveness of our proposed Spherical DNNs for spherical handwritten digit classification and sport classification, saliency detection and gaze tracking in 360° videos.
The capacity of discriminating between normal and impaired dynamic cerebral autoregulation (dCA), based on spontaneous fluctuations in arterial blood pressure (ABP) and cerebral blood flow (CBF), has considerable clinical relevance. This study aimed to quantify the separate contributions of vascular resistance and compliance as parameters that could reflect myogenic and metabolic mechanisms to dCA.
Forty-five subjects were studied under normo and hypercapnic conditions induced by breathing a mixture of 5% carbon dioxide in air. Dynamic cerebrovascular resistance and compliance models with ABP as input and CBFV as output were fitted using Genetic Algorithms to identify parameter values for each subject, and respiratory condition.
The efficiency of dCA was assessed from the models generated CBFV response to an ABP step change, corresponding to an autoregulation index of 5.561.57 in normocapnia and 2.381.73 in hypercapnia, with an area under the ROC curve (AUC) of 0.9 between both conditions. Vascular compod flow, Genetic Algorithms, hypercapnia.
An imaging device to locate functionalized nanoparticles, whereby therapeutic agents are transported from the site of administration specifically to diseased tissues, remains a challenge for pharmaceutical research. Here, we show a new method based on electrical impedance tomography (EIT) to provide images of the location of gold nanoparticles (GNPs) and the excitation of GNPs with radio frequencies (RF) to change impedance permitting an estimation of their location in cell models Methods We have created an imaging system using quantum cluster GNPs as a contrast agent, activated with RF fields to heat the functionalized GNPs, which causes a change in impedance in the surrounding region. This change is then identified with EIT.
Images of impedance changes of around 804% are obtained for a sample of citrate stabilized GNPs in a solution of phosphate-buffered saline. learn more A second quantification was carried out using colorectal cancer cells incubated with culture media, and the internalization of GNPs into the colorectal cancer cells was undertaken to compare them with the EIT images. When the cells were incubated with functionalized GNPs, the change was more apparent, approximately 402%. This change was reflected in the EIT image as the cell area was more clearly identifiable from the rest of the area.
EIT can be used as a new method to locate functionalized GNPs in human cells and help in the development of GNP-based drugs in humans to improve their efficacy in the future.
EIT can be used as a new method to locate functionalized GNPs in human cells and help in the development of GNP-based drugs in humans to improve their efficacy in the future.
In patients treated with noninvasive ventilation, sleep-related breathing changes can modify patient-ventilator interactions which could reduce its effectiveness. The aim of this prospective observational study was to determine the impact of sleep/wake state on leaks, upper airway obstructive events, and asynchronies, in patients treated by long-term noninvasive ventilation.
Stable patients adapted to noninvasive ventilation were considered for nocturnal polysomnography. Unintentional leaks, upper airway obstructive events, and asynchronies were compared between sleep and awake periods.
Twenty-eight patients were enrolled. Underlying diagnoses were neuromuscular disease (n=11), chest wall disease (n=8) and obesity-hypoventilation (n=9). Leaks were more frequent in sleep than in awake periods, with a median of 10% (IQR 0-75%)
1% (IQR 0-9%) of time (p<0.001), respectively. During sleep, asynchronies with and without associated leak affected 27% of breaths (IQR 16-39%), compared to non-leak-related aidering that in patients with low sleep efficiency respiratory events could be underestimated if sleep is not evaluated.
The aim of this study is to determine the extent of agreement between self-reported measurements of total sleep time (TST) and actigraphy in the fire and emergency services occupation.
Twenty-four firefighters participated in an 18-day study. Four measurements were used to assess TST PSQI, a newly developed habitual Extended Sleep Survey, a newly developed daily Emergency Services Sleep Diary (ESSD), and actigraphy. The Extended Sleep Survey and ESSD were constructed to address the specific job-related characteristics of fire and emergency services that other measurements cannot achieve (e.g., multiple sleep bouts in a single night).
The PSQI TST is least accurate compared to actigraphy. The Extended Sleep Survey TST shows improvement over PSQI TST, but was statistically different from actigraphy TST. No difference in mean TST was found between ESSD TST and Actigraphy TST. Furthermore, ESSD TST and Actigraphy TST correlated strongly together.
Without modification, traditional self-reported measures may not be appropriate in the fire and emergency service occupation. This study suggests that the ESSD may serve as a useful alternative to actigraphy to measure TST.
Without modification, traditional self-reported measures may not be appropriate in the fire and emergency service occupation. This study suggests that the ESSD may serve as a useful alternative to actigraphy to measure TST.Primary central sleep apnea (CSA) is classified as non-hypercapnic CSA. High loop gain, lower carbon dioxide (CO2) reserves, and other reasons can lead to hypocapnia in patients who develop intermittent hyperventilation during sleep. Therefore, it is necessary to monitor nocturnal CO2 level for these patients. We report a female patient diagnosed with non-hypercapnic primary CSA who complained of snoring, apnea, and excessive daytime sleepiness. With the monitoring of transcutaneous partial pressure of CO2 (PtcCO2), manual non-invasive ventilation (NIV) pressure titration was performed with continuous positive airway pressure (CPAP), bilevel positive airway pressure in a spontaneous-timed mode (BPAP-ST), and adaptive servo-ventilation (ASV) mode for three nights, respectively. Only ASV mode could stabilize the PtcCO2 above the apneic threshold (AT, approximately 40 mmHg) with successfully eliminating central apnea events. It is concluded that the level of CO2 is the determinant of successful NIV pressure titration in patients with non-hypercapnic CSA.
To identify the association between insomnia symptoms and signs of prodromal neurodegeneration, including an analysis of potential differences between sleep-onset and sleep-maintenance insomnia.
We included those aged 45-85 years, living in one of 10 Canadian provinces in between 2012-2015 (at the baseline), recruited via three population-based sampling methods. Insomnia symptoms were assessed using questions adapted/modified from the Pittsburgh Sleep Quality Index. A panel of potential prodromal neurodegenerative markers including self-reported symptoms and objective gait motor, cognitive, and autonomic variables were assessed cross-sectionally. We compared those who endorsed insomnia symptoms ≥3 times per week to controls, adjusting for age, sex and education via logistic regression.
Overall, 2,051/30,097 people screened positive for sleep-onset insomnia alone and 4,333 for sleep-maintenance insomnia alone, while 2,371 endorsed both subtypes. On objective gait tests, participants with sleep-onset insored to maintenance insomnia, those with sleep-onset insomnia have more motor, cognitive and autonomic signs/symptoms. When evaluating neurodegenerative risk, differentiating insomnia subtypes may increase precision.
We determined the relationship of cardiovascular risk factors (CRF), cardiovascular diseases (CVD), nocturnal blood pressure (NBP) and nocturnal blood pressure fluctuations (NBPFs) with the severity of obstructive sleep apnea (OSA). We also investigated the effect of short-term continuous positive airway pressure (CPAP) therapy on NBP parameters.
This retrospective study included 548 patients from our cardiac clinic with suspected OSA. Patients underwent polysomnography and continuous NBP measurement using the pulse transit time (PTT). According to their apnea-hypopnea index (AHI), patients were subclassified Controls (AHI < 5/h), mild (AHI 5 - < 15/h), moderate (AHI 15 - < 30/h) and severe OSA (AHI ≥ 30/h). 294 patients received CPAP therapy.
Analysis of covariance (ANCOVA) showed that NBP and the frequency of NBPFs were the highest in severe followed by moderate and mild OSA (all p < 0.001). Multivariable regression analysis revealed a significant association of NBPFs with AHI, BMI, systolbstructive sleep apnea; Identifier DRKS00024087; URL https//www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00024087.
To evaluate the impact of COVID-19 pandemic on insomnia and other sleep disturbances in health care professionals.
A survey was distributed using social media and organizational emails to Brazilian active health care professionals during the COVID-19 outbreak. We explored potential associated factors including age, gender, occupation, workplace, work hours, income, previous infection with COVID-19, recent/current contact with COVID-19 patients, regional number of incident deaths, anxiety, and burnout. We evaluated new-onset/ previous insomnia worsening episodes (primary outcome), new pharmacological treatments, sleep quality, duration, nightmares and snoring (secondary outcomes).
A total of 4,384 health professionals from all regions of the country were included in the analysis (44±12 years, 76% females, 53.8% physicians). Overall, 55.7% were assisting patients with COVID-19, and 9.2% had a previous COVID-19 infection. The primary outcome occurred in 32.9% of respondents in parallel to 13% new pharmacological treatments for insomnia.
My Website: https://www.selleckchem.com/Androgen-Receptor.html
|
Notes.io is a web-based application for taking notes. You can take your notes and share with others people. If you like taking long notes, notes.io is designed for you. To date, over 8,000,000,000 notes created and continuing...
With notes.io;
- * You can take a note from anywhere and any device with internet connection.
- * You can share the notes in social platforms (YouTube, Facebook, Twitter, instagram etc.).
- * You can quickly share your contents without website, blog and e-mail.
- * You don't need to create any Account to share a note. As you wish you can use quick, easy and best shortened notes with sms, websites, e-mail, or messaging services (WhatsApp, iMessage, Telegram, Signal).
- * Notes.io has fabulous infrastructure design for a short link and allows you to share the note as an easy and understandable link.
Fast: Notes.io is built for speed and performance. You can take a notes quickly and browse your archive.
Easy: Notes.io doesn’t require installation. Just write and share note!
Short: Notes.io’s url just 8 character. You’ll get shorten link of your note when you want to share. (Ex: notes.io/q )
Free: Notes.io works for 12 years and has been free since the day it was started.
You immediately create your first note and start sharing with the ones you wish. If you want to contact us, you can use the following communication channels;
Email: [email protected]
Twitter: http://twitter.com/notesio
Instagram: http://instagram.com/notes.io
Facebook: http://facebook.com/notesio
Regards;
Notes.io Team