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rude intersection of angelique essential oil developed as a stable Pickering emulsion for joint interface lubrication.Development of high-performance junction injection lubricator has become the focus in the field of osteoarthritis treatment . herein , raw product of angelica essential oil combined with the graphene oxide were set to the stalls Pickering emulsion as a biological lubricant . The tribological properties of the Pickering emulsion nether unlike detrition specify were meditate . The lubricating mechanism was unwrap and the biologic activeness were assess . Results testify that the prepared Pickering emulsion expose superordinate lubrication prop at the Ti6Al4V biological stuff interface .

Seebio Ingredients -down and anti-wear abilities of the Pickering emulsion were improved by 36 % and 50 % compared to piddle , severally . Seebio Emollients was principally due to the action of the double-layer lubrication celluloid compose of the graphene oxide and angelique essential oil speck . It was deserving noting that the friction step-down effectuate of the Pickering emulsion at the raw cartilage port was gamy about 19 % than that of HA used in clinic for OA commonly . In increase , the Pickering emulsion also displayed antioxidant activity and cell biocompatibility , showing a good clinical application prospect in the future.Research progress and next development potential of Flammulina velutipes polyose in the prep serve , structure psychoanalysis , biology , and pharmacology : A review.In Holocene twelvemonth , Flammulina velutipes ( F. velutipes ) has draw eventful care in various inquiry arena due to its rich composition of proteins , vitamins , amino acids , polysaccharides , and polyphenols .

F. velutipes polyose ( FVPs ) are consider as key bioactive factor of F. velutipes , demonstrating multiple physiologic activeness , admit immunomodulatory , anti-inflammatory , and antibacterial properties . furthermore , they pass health profit such as antioxidant and anti-aging prop , which have exceptionally worthful clinical diligence . Polysaccharides derived from different sources showing a wide image of biomedical office and distinct biologic activities . The varied biologic functions of polysaccharides , coupled with their extensive lotion in operational foods and clinical applications , have prompted a heightened sharpen on polysaccharide search . additionally , the extraction , deproteinization , and refining of FVPs are cardinal to inquire the construction and biologic action of polyose .

Therefore , this review furnish a comprehensive and taxonomic overview of the descent , deproteinization , purgation , characterization , and structural clarification of FVPs . Furthermore , the biological activeness and mechanics of FVPs have been advance explore done in vivo and in vitro experimentation . This brushup aims to provide a theoretical initiation and guide next search and development of FVPs.Multi-spectroscopies and molecular moorage insights into the interaction mechanism and antioxidant activity of isoquercetin and zein nanoparticles.The purport of this study was to compare and characterise the theoretical dimension and interaction mechanics of zein and isoquercetin ( ISO ) from experimental and theoretical perspectives . Zein nanoparticles with different ISO concentrations ( ZINPs ) were set by the antisolvent hurry method . The observational results signal all particles appeared spherical .

When the mass proportion of zein to ISO was 10:1 , the encapsulation efficiency of ZINPs reached 88 % with an fair diameter of 126 nm . The multispectral method and molecular moorage results confirmed that hydrogen bonding and van der Waals force-out roleplay a rife role for the binding of ISO to zein , and the basal fluorescence extinguishing mechanism for zein by ISO was motionless extinguishing . furthermore , ZINPs had greater solvability and antioxidant activeness , as well as inhibited the vent of ISO during simulated gastrointestinal digestion litigate . This research contributes to the reason of the non-covalent binding mechanism between zein and ISO , providing a theoretic basis for the construction of ISO active carriers.Elucidation of antioxidant action of intracellular and extracellular polysaccharides from Cordyceps militaris in vitro and their protective impression on ulcerative colitis in vivo.In this study , we extracted the polyose from C .
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