Notes

Anti-Inflammatory Outcomes of Resveratrol on Man Retinal Color Tissues as well as a Myopia Canine Style.
The maximum adsorption capacities of 2FPL, 4FPL, and 6FPL for MO were found to be 775.19, 826.44, and 833.33 mg/g, respectively. Detailed adsorption studies confirm that the higher adsorption capacity of 6FPL is due to the fast exchange of anions (NO3 -) by MO in the interlayers of MAN-LDH, larger surface area, hydrogen bonding, and electrostatic interaction between adsorbate and adsorbent. The thermodynamic data indicate that the adsorption behavior is spontaneous and endothermic in nature. The reusability of all FPL adsorbents is observed to be excellent. The MAN-LDH recoated after the 31st-cycle nanocomposites show a recovery of 100% adsorption efficiency, similar to the freshly prepared 6FPL. Such systematic studies greatly help in advancing the applications of newly functionalized nanomaterials toward eco-remediation approaches. Copyright © 2020 American Chemical Society.An in-house UV lithography setup has been optimized to fabricate low-cost disposable electrochemical sensing Cu electrodes using a copper clad board. In view of the high oxidation probability of copper, the low-cost electrodes were modified using different gold nanostructures and a conducing polymer PEDOTPSS to attain maximal signal output and improved shelf-life. Zero-dimensional (0D) gold nanoparticles (∼40 nm) and three-dimensional (3D) gold nanoflowers (∼38 nm) mixed with PEDOTPSS were used as signal-enhancing conductors for the ultrasensitive detection of our model contaminant, methylene blue dye (MB). The bare copper electrode was sensitive to MB, linearly within the range of 4-100 μM, with a limit of detection of 3.49 μM. While for gold nanoparticle-PEDOTPSS-modified electrode, the sensitivity of the electrode was found to increase linearly in the range of 0.01-0.1 μM, and for gold nanoflowers-PEDOTPSS, the sensitivity achieved was 0.01-0.1 μM with the LOD as 0.0022 μM. For a PEDOTPSS-modified Cu electrode, used as a comparative to study the contributing role of gold nanostructures towards improved sensitivity, the linearity was found to be in the range of 0.1-1.9 μM with the LOD as 0.0228 μM. A 6 times improvement in signal sensitivity for the nanoflower-PEDOTPSS electrode compared to the nanoparticle-PEDOTPSS-modified electrode indicates the influence of nanoparticle shape on the electrode efficiency. 3D gold nanoflowers with a large surface area-to-volume ratio and a high catalytic activity prove to be a superior choice for electrode modification. Copyright © 2020 American Chemical Society.Successful surgeries involving orthopedic implants depend on the avoidance of biofilm development on the implant surface during the early postoperative period. Here, we investigate the potential of novel antibacterial compounds-second-generation lipophosphonoxins (LPPOs II)-as additives to surgical bone cements. We demonstrate (i) excellent thermostability of LPPOs II, which is essential to withstand elevated temperatures during exothermic cement polymerization; (ii) unchanged tensile strength and elongation at the break properties of the composite cements containing LPPOs II compared to cements without additives; (iii) convenient elution kinetics on the order of days; and (iv) the strong antibiofilm activity of the LPPO II-loaded cements even against bacteria resistant to the medicinally utilized antibiotic, gentamicin. Thus, LPPOs II display promising potential as antimicrobial additives to surgical bone cements. Copyright © 2020 American Chemical Society.Herein, two bifunctional macromolecular aromatic epoxy resins (ERs), namely, 4,4'-isopropylidenediphenol oxirane (ERH) and 4,4'-isopropylidene tetrabromodiphenol oxirane (ERBr), are synthesized, characterized, and evaluated as anticorrosive materials for carbon steel corrosion in acidic medium. ERs were characterized using proton nuclear magnetic resonance (1H NMR) and Fourier transform infrared spectroscopy techniques. Investigated ERs acted as effective corrosion inhibitors, and their inhibition effectiveness followed the order ERBr (96.5%) > ERH (95.6%). Potentiodynamic polarization results showed that ERH and ERBr behave as predominantly anodic type and the cathodic type of corrosion inhibitors, respectively. Adsorption of both the studied ERH and ERBr molecules obeyed the Langmuir adsorption isotherm model. Density functional theory and molecular dynamics studies showed that protonated forms of ERH and ERBr contribute more to metal (carbon steel)-inhibitor (ERH/ERBr) interactions than their neutral forms. Copyright © 2020 American Chemical Society.We developed a novel fabrication method for nanochannels that are easily scaled up to mass production by selectively growing zinc oxide (ZnO) nanostructures and covering using a flat PDMS surface to make hollow nanochannels. Nanochannels are used in the biotechnological and environmental fields, being employed for DNA analysis and water purification, due to their unique features of capillary-induced negative pressure and an electrical double-layer overlap. However, existing nanochannel fabrication methods are complicated, costly, and not amenable to mass production. Here, we developed a novel nanochannel fabrication method. The pillar-like dense ZnO nanostructures were grown in a solution process, which is easily applicable to mass production. The size of the fabricated ZnO nanostructures has a thickness of 30-300 nm and a diameter on the order of 102 nm, which are easily adjusted by synthesis times. The ZnO nanostructures were covered by the flat polydimethylsiloxane (PDMS) surface, and then the cracks between ZnO nanostructures served as hollow nanochannels. Because the suggested fabrication process has no thermal shrinkage, the process has higher production efficiency than existing nanochannel mass production methods based on the thermal/pressure process. The mechanical strength of the fabricated ZnO nanostructures was tested with repetitive tape peeling tests. Finally, we briefly verified the nanochannel performance by applying the nanochannel to the micro/nanofluidic system, whose performance is easily evaluated and visualized by current-voltage relation. Copyright © 2019 American Chemical Society.One of the serious problems in the oil industry is precipitation and deposition of asphaltenes in the different oil production stages including formation, wellbore, production tubing, flow lines, and separation units. This phenomenon causes a dramatic increase in the cost of oil production, processing, and transferring. Thus, it seems to be very necessary to use the removing methods for precipitated asphaltenes in different crude oil production and transferring stages. In this study, the ability of microorganisms for biodegradation of precipitated asphaltenes was investigated. For this purpose, four bacterial consortiums were isolated from oil-contaminated soil, crude oil, reservoir water, and oil sludge samples of an oil field located in the southwest of Iran. Based on the results of the designed experiments, by using response surface methodology (RSM) and central composite design, the bacterial consortiums were cultured in the flasks. Three levels of temperatures, salinity, pH, and initial asphaltene concenmedium were optimized by RSM, and besides, their effects on the performance of bacteria in the asphaltene biodegradation process were discussed. The validity of some available kinetic models to describe the behavior of the studied bacteria consortium was investigated, and it was observed that Tessier, Moser, and Contois models accurately predict the values of asphaltenes and biomass concentration at 30, 45, and 60 °C, respectively. Copyright © 2020 American Chemical Society.In the last three decades, there has been a huge increase in the number of antibiotic-resistant bacterial strains, which is becoming a serious threat to public health. Since the discovery of new effective antibiotics has dramatically decreased in last ten years, there are huge initiatives to develop new antimicrobial approaches to fight drug-resistant bacterial infections. In the last decade, a new nanoparticle-based tool has emerged to combat deadly bacterial infections, which may overcome the barriers faced by antibiotic resistance. The current mini-review highlights recent reports on two-dimensional (2D) graphene oxide (GO), 2D transition metal dichalcogenides (TMD), 2D MXenes, and 2D heterostructure material-based approaches to tackle bacteria. Notably, we discuss the major design criteria which have been used to develop novel antimicrobial 2D and heterostructure materials to eliminate bacterial infections. Next, details on the various mechanisms underlying antibacterial activity for 2D and heterostructure materials such as physical/mechanical damage, lipid extraction, oxidative stress, and photothermal/photodynamic effects have been discussed. Finally, we highlight the promises, major challenges, and prospects of nanomaterial-based approaches to combat multidrug-resistant bacterial infections. Copyright © 2020 American Chemical Society.Antibiotic resistance is a massive and serious threat to human welfare and healthcare. Apart from being genetically resistant to antibiotics, the other important mechanism by which bacteria can evade antibiotics is multidrug tolerance. Here cells enter into a transiently nongrowing phase, and as a result, latent infection remains inside the host, causing disease recurrence. EGFR inhibitor Biofilm-derived antibiotic tolerance and persister formation of the pathogenic bacteria inside the host remain a serious issue of treatment failure and recurrent chronic infection in the case of all major pathogens. As a result, new chemotherapeutic agents are sought that specifically inhibit biofilm formation or maturation as well as cause the dispersion of mature biofilms, thus allowing the conventional drugs to kill sensitive cells residing inside. This mini-review attempts to analyze different small-molecule-based chemical approaches that have been used to enable bacterial biofilm inhibition at different steps of maturation. Copyright © 2020 American Chemical Society.This mini review focuses on the effect of preparation technologies on the piezoelectric property of KNN-based materials. The piezoelectric properties of KNN-based ceramics can be optimized by controlling the condition for sintering and poling processes. The preparation method of textured and single crystals could realize an increased piezoelectric constant compared to that of corresponding ceramics. According to current developments in preparation technology, we also provide perspectives and outlooks of lead-free KNN-based materials. Copyright © 2020 American Chemical Society.In the immersion precipitation process for membrane formation, a polymer casting film is placed in contact with a nonsolvent in a coagulation bath; an essential feature of the membrane formation process is the foray into the metastable region of the ternary phase diagram for the nonsolvent/solvent/polymer system. The primary objective of this article is to trace the origins of such forays. The Maxwell-Stefan diffusion formulation is combined with the Flory-Huggins description of phase equilibrium thermodynamics to set up a model for describing the transient equilibration trajectory that is followed in the polymer casting film. Four different systems are analyzed water/acetone/CA, water/DMF/PVDF, water/NMP/PSF, and water/NMP/PEI (CA = cellulose acetate; PVDF = poly(vinylidene fluoride); PSF = polysulfone; PEI = polyetherimide, DMF = dimethyl formamide; NMP = N-methyl-2-pyrrolidone). The analysis shows that diffusional forays are mainly engendered due to thermodynamic coupling effects; such effects are quantified by the set of thermodynamic factors , where a i , the activity of species i, is dependent on the volume fractions, ϕ i and ϕ j , of both nonsolvent (i) and solvent (j).
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