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Primary Objective To compare child- and parent-report ratings on the Health Behavior Inventory, Revised Child Anxiety and Depression Scale-Short Version (anxiety subscale), Patient Health Questionnaire-9, and Pediatric Quality of Life InventoryTM among children with persistent post-concussive symptoms following a sports- or recreation-related concussion, overall and by child age and gender.Research Design Cross-sectional study examining baseline data from a randomized, comparative effectiveness trial.Methods and Procedures Inter-rater reliability was assessed using two-way random effects model (absolute agreement) intraclass correlations, correlations were examined using Spearman's rho, mean differences were determined using paired t-tests, and agreement was examined using Bland-Altman plots.Main Outcomes and Results The final analytic sample was 200 parent-child dyads [child Mage = 14.7 (95% CI 14.5, 15.0)]. Reliability and correlations were modest overall. When considering child age and gender, reliability ranged from poor to excellent (-1.01-0.95) and correlations ranged from weak to strong (-0.64-0.94). Overall, children reported more symptoms but better functioning than parents, and mean differences in scores were greater among females (versus males) and ages 16-18 (versus younger groups).Conclusions Findings should inform the use and interpretation of psychosocial measures when developing appropriate youth concussion treatment plans.
With the increasing drilling depth of shale formation, downhole collapse is a frequent occurrence, which often manifests as borehole wall caving.

We used the deep shale of the Longmaxi Formation to conduct the mechanical loading and unloading experiments under different downhole working conditions and a theoretical evaluation method of borehole wall caving and instability was proposed.

As the confining pressure and axial load increased, the acoustic velocity increased. When a certain value was reached, the acoustic velocity of the rock mass had minimal changes. As the confining pressure continued to unload and decrease, the acoustic velocity decreased. At the moment of core failure, the acoustic velocity suddenly dropped. When the axial force of loading was constant, the unloading speed of confining pressure increased, and shale could easily be destroyed. The pressure at the well bottom changed rapidly, the likelihood of borehole wall failure increased.

The deep shale has high brittleness. Under the bnd turning the pump off, the shale tensile stress in the upper and lower sidewalls of the horizontal well section was responsible for tensile caving.
The aims of this study were (1) to examine the associations between self-reported health-related quality of life (HRQoL), health-related physical fitness (cardiorespiratory fitness, muscular strength, and speed-agility), and mode of commuting to and from school in Spanish children, and separately by gender and (2) to analyse the difference in cardiorespiratory fitness by mode of commuting to and from school by gender.

We conducted a cross-sectional analysis that included 415 children aged 8.47 ± 0.36 years from 14 schools in Granada, Spain. The HRQoL outcome was assessed using the valid and reliable KINDL-R questionnaire, which covers six life dimensions, children's physical fitness was assessed using the ALPHA fitness test battery, and while commuting to and from school was assessed using the valid, reliable, and feasible 'Mode and Frequency of Commuting To and From School Questionnaire'.

Cardiorespiratory fitness was positively correlated with all dimensions of HRQoL in boys, whereas higher muscular sding long jump) was positively correlated with the emotional wellbeing dimension only in girls. Active commuting to and from school was associated with higher levels of cardiorespiratory fitness, school dimension, and KINDL-R total score. Improving cardiorespiratory fitness might be especially useful to improve HRQoL in children, and vice versa.
Wearable devices are a new strategy for promoting physical activity in a free-living condition that utilizes self-monitoring, self-awareness, and self-determination. The main purpose of this study was to explore health benefits of commercial wearable devices by comparing physical activity, sedentary time, sleep quality, and other health outcomes between individuals who used and those that did not use commercial wearable devices.

The research design was a cross-sectional study using an Internet survey in Taiwan. Self-administered questionnaires included the International Physical Activity Questionnaire-Short Form, Pittsburgh Sleep Quality Index, Health-Promoting Lifestyle Profile, and World Health Organization Quality-of-Life Scale.

In total, 781 participants were recruited, including 50% who were users of wearable devices and 50% non-users in the most recent 3 months. Primary outcomes revealed that wearable device users had significantly higher self-reported walking, moderate physical activity, and total physical activity, and significantly lower sedentary time than non-users. Wearable device users had significantly better sleep quality than non-users.

Wearable devices inspire users' motivation, engagement, and interest in physical activity through habit formation. Wearable devices are recommended to increase physical activity and decrease sedentary behavior for promoting good health.
Wearable devices inspire users' motivation, engagement, and interest in physical activity through habit formation. Wearable devices are recommended to increase physical activity and decrease sedentary behavior for promoting good health.A new highly oxygenated ent-atisane diterpenoid, namely excagallonoid A (1), together with five known analogues (2 - 6) were isolated from the leaves and twigs of Excoecaria agallocha. Their structures were elucidated on the basis of extensive spectroscopic analyses (HRESIMS, UV, IR, 1 D and 2 D NMR), and the absolute configurations of 1 and 5 were determined by single-crystal X-ray diffraction. Compound 1 represents the first example of an ent-atisane diterpenoid featuring a vicinal 2,3-diol moiety. Compounds 1 and 4 exhibited weak cytotoxicities in vitro against RKO colon cancer cells with IC50 values of 28.7 ± 1.98 and 32.6 ± 2.81 µM, respectively.Lymphedema is manifested as a chronic swelling arising due to stasis in the lymphatic flow. see more No cure is currently available. A non-invasive treatment is a 3 week complete decongestive therapy (CDT), including manual lymphatic drainage and compression bandaging to control swelling. As CDT leads to mobilization of several liters of fluid, effects of CDT on hyaluronan clearance (maker for lymphatic outflow), volume regulating hormones, total plasma protein as well as plasma density, osmolality and selected electrolytes were investigated. In this pilot study, we assessed hyaluronan and volume regulating hormone responses from plasma samples of nine patients (three males, six females, aged 55 ± 13 years) with lower limb lymphedema stage II-III, before - and after - CDT. A paired non-parametric test (Wilcoxon) was used to assess hormonal and plasma volume changes. Correlation was tested using Spearman's correlation. The main findings of this novel study are that lymphedema patients lost volume and weight after therapy. Hyaluronic acid did not significantly change pre- compared to post-CDT. Aldosterone increased significantly after therapy, while plasma renin activity increased, but not significantly. Plasma total protein, density, osmolality and sodium and chloride did not show differences after CDT. To our knowledge, no study has previously investigated the effects of CDT on volume regulating hormones or electrolytes. To identify the time-course of volume regulating hormones and lymphatic flow changes induced by CDT, future studies should assess these parameters serially over 3 weeks of therapy.Sarcopenia is associated with obesity and might also be responsible for other disorders. Here, we investigated the prevalence of sarcopenia and its predictors in obese subjects. Subjects who underwent a medical health checkup and living-related liver donors were recruited. Obesity was defined as body mass index (BMI) ≥25 kg/m2. Muscle mass was assessed using computed tomography at the 3rd lumbar vertebra. The lowest quartile of the lumbar skeletal muscle index (LSMI) was considered sarcopenia. Among 466 obese subjects, 53 (11.4%) had sarcopenia. Subjects with sarcopenia were significantly older (mean 66.6 vs. 53.3 years) and had a significantly higher prevalence of hypertension (62.3 vs. 46.0%) and diabetes (45.3 vs. 31.0%), higher fibrosis-4 (FIB-4) index (mean 1.57 vs. 1.16), and higher atherosclerotic cardiovascular disease (ASCVD) risk score (mean 22.86% vs. 11.15%), whereas they had a significantly lower prevalence of female gender (13.2% vs. 27.8%), lower BMI (mean 26.4 vs. 27.4 kg/m2), and lower LSMI (mean 43 vs. 56 cm2/m2) than subjects without sarcopenia (all P  less then  0.05). On multivariate analysis, higher BMI (odd ratio [OR] = 0.599, P = 0.001) was independently associated with a reduced risk of sarcopenia, whereas higher ASCVD risk scores (OR = 1.045, P  less then  0.001) were independently associated with an increased risk of sarcopenia. Sarcopenia is significantly associated with lower BMI and higher cardiovascular risk in an obese Asian population.
Limited data are available to guide cardiovascular screening in adult or masters athletes (≥35 years old). This review provides recommendations and the rationale for the cardiovascular risk assessment of older athletes.

Review of available clinical guidelines, original investigations, and additional searches across PubMed for articles relevant to cardiovascular screening, risk assessment, and prevention in adult athletes (1990-2020).

Clinical review.

Level 3.

Atherosclerotic coronary artery disease (CAD) is the leading cause of exercise-induced acute coronary syndromes, myocardial infarction, and sudden cardiac death in older athletes. Approximately 50% of adult patients who experience acute coronary syndromes and sudden cardiac arrest do not have prodromal symptoms of myocardial ischemia. The risk of atherosclerotic cardiovascular disease (ASCVD) can be estimated by using existing risk calculators. ASCVD 10-year risk is stratified into 3 categories low-risk (≤10%), intermediate-risk (between 10% anological therapy.
We propose a comprehensive risk assessment for older athletes that combines conventional and novel risk factors for ASCVD, a 12-lead resting electrocardiogram, and a CAC score. Available risk calculators provide a 10-year estimate of ASCVD risk allowing for risk stratification and targeted management strategies. CAC scoring can refine risk estimates to improve the selection of patients for initiation or avoidance of pharmacological therapy.Dirofilaria immitis causes life-threatening heart disease in dogs, thus screening of dog populations is important. Lens-free technology (LFT) is a low-cost imaging technique based on light diffraction that allows computerized recognition of small objects in holographic images. We evaluated an algorithm capable of recognizing microfilariae in canine whole blood using the LFT. We examined 3 groups of 10 EDTA blood specimens, from dogs with microfilaremia (group A), healthy dogs (B), and dogs with hematologic modifications other than microfilaremia (C). The LFT analyzer photographed repeated series of 5 images of all samples. The algorithm declared a sample positive if a microfilaria was detected on ≥1, ≥2, or ≥3 of the 5 images of a series. Microfilariae were detected visually in the images in 9 of 10 cases in group A; no microfilariae were seen in the images from groups B and C. Of the 30 cases, there were 14, 4, and only 3 false-positives with the 1 of 5, 2 of 5, and 3 of 5 image cutoffs, respectively. There were no false-negatives, regardless of cutoff.
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