Notes

Effects of Tryptophan Using supplements and Exercise for the Destiny associated with Kynurenine Metabolites inside Rodents as well as Human beings.
Whether the level of popultion aging is lower or higher than the threshold value of 0.12937, the population aging has a negative coefficient on carbon emissions. Moreover, the higher the level of population aging, the greater the offsetting effect of population aging on carbon emission. When the level of trade openness is below the threshold value of 0.30990, the effect of population aging on carbon emission is negligible. When the level of trade openness is higher than the threshold value of 0.30990, the offesetting effect of population aging on carbon emission begins to appear. In other words, population aging has an offsetting effect on carbon emission when trade openness is in relatively high level, whereas the offsetting effect disappears when trade openness is lower than threshold value.Light-absorbing impurities (LAIs), including black carbon (BC) and mineral dust, in snow can trigger a positive feedback. In this study, we estimate the contribution of BC and dust to glacial melting in Central Asia. Average BC and dust concentrations in the surface snow of the Muz Taw glacier are 1788 ± 1754 ng g-1 and 172 ± 178 μg g-1, respectively. Simulation using the Snow Ice and Aerosol Radiation (SNICAR) model indicates that the combined effect of BC and dust reduces the snow albedo by approximately 6.24% to 50.4% relative to clean snow. Radiative forcing (RF) induced by BC and dust deposited in snow ranges from 1.61 to 32.69 W m-2, with an average of 16.74 W m-2 for the central scenario. Thus, glacier melting can be enhanced by 36.37 cm w.e. by BC and dust in snow, accounting for about 16.3% of the total glacier melt. LAIs deposited on the Muz Taw glacier mostly originate from Central Asia, West Siberia and local emissions during the study period. More than 80% of BC deposited is attributed to anthropogenic emissions. These results strengthen the important role of BC and dust in glacier melting in Central Asia, and further highlights the potential benefits of mitigation of BC emissions.This work is aimed to investigate the effect of research and development (R&D) on reduce in environmental pressures through an empirical analysis of the top six global carbon emitters (the C6 China, USA, India, Russia, Japan, and Germany). This work is valuable toward carbon reduction within C6 countries and the world (C6 emit roughly 60% of the global carbon emissions). Moreover, it is also meaningful for exploring the decoupling of economic development from carbon emissions in other areas (both developing and developed countries). The main findings displayed that the decoupling status in developed countries (i.e., USA, Japan, and Germany) were better and more stable than in developing countries (i.e., China, India, and Russia). Germany performed best among the developed countries, and China performed most stable among the developing countries. The effect of the per capita R&D expenditure was main resistance to decoupling carbon emissions from economic development in C6 countries. However, the energy intensity effect and R&D efficiency effect related to technological progress were the main driving forces for the decoupling process. Consequently, this study proposes that the improvement of technological progress should be prioritized.There is increasing interest in understanding potential impacts of complex pollutant profiles to long-lived species such as the green sea turtle (Chelonia mydas), a threatened megaherbivore resident in north Australia. Dietary ingestion may be a key exposure route for metals in these animals and marine plants can accumulate metals at higher concentrations than the surrounding environment. We investigated concentrations of 19 metals and metalloids in C. mydas forage samples collected from a group of offshore coral cays and two coastal bays over a period of 2-3 years. Although no samples exceeded sediment quality guidelines, coastal forage Co, Fe, and V concentrations were up to 2-fold higher, and offshore forage Sr concentrations were ~3-fold higher, than global seagrass means. Principal Component Analysis differentiated coastal bay from coral cay forage according to patterns consistent with underlying terrigenous-type or marine carbonate-type sediment geochemistry, such that coastal bay forage was higher in Fe, Co, Mn, Cu, and Mo (and others) but forage from coral cays was higher in Sr and U. Forage from the two coastal bays was differentiated according to temporal variation in metal profiles, which may be associated with a more episodic sediment disturbance regime in one of the bays. For all study locations, some forage metal concentrations were higher than previously reported in the global literature. Our results suggest that forage metal profiles may be influenced by the presence of some metals in insoluble forms or bound to ultra-fine sediment particles adhered to forage surfaces. Metal concentrations in Great Barrier Reef forage may be present at levels higher than expected from the global seagrass literature and appear strongly influenced by underlying sediment geochemistry.Fall armyworm (FAW) is a new invasive pest that is causing devastating effects on maize production and threatening the livelihoods of millions of poor smallholders across sub-Saharan Africa and Asia. Using unique survey data from 2356 maize-growing households in Ghana, Rwanda, Uganda, Zambia and Zimbabwe, we examined how smallholder farmers are fighting this voracious pest. In particular, we assessed the FAW management strategies used by smallholders, socio-economic factors driving the choice of the management options, the complementarities or tradeoffs among the management options, and the (un)safe pesticide use practices of farmers. Results showed that smallholder farm households have adopted a variety of cultural, physical, chemical and local options to mitigate the effects of FAW, but the use of synthetic pesticides remains the most popular option. Results from multivariate probit regressions indicated that the extensive use of synthetic pesticides is driven by household asset wealth, and access to subsidised farm inputs and extension information. We observed that farm households are using a wide range of pesticides, including highly hazardous and banned products. Unfortunately, a majority of the households do not use personal protective equipment while handling the pesticides, resulting in reports of acute pesticide-related illness. Our findings have important implications for policies and interventions aimed at promoting environmentally friendly and sustainable ways of managing invasive pests in smallholder farming systems.Mining activities at Duparquet in Western Quebec (Canada) have significantly affected the local environment and left behind significant amounts of metals. Monitoring this contamination is essential to infer its past and present impacts on environmental quality and to evaluate the resulting human exposure. In that context, we measured long time series of Pb concentrations and their corresponding stable isotope ratios in long-lived white cedars (Thuja occidentalis L.) growing at Duparquet Lake in order to evaluate potential time variations of the Pb environmental contamination as well as to identify the responsible source(s). Tanshinone I Results show that before 1950, Pb at Duparquet is mostly terrigenous. Lead concentrations rapidly increase afterwards. A simultaneous shift to lower 206Pb/207Pb ratios identifies the smelting of Abitibi ores as the source of contamination. An isotope mass balance model evaluates at roughly 7.5-20%, 5-40%, 5-9% and less then 3% the Pb contributions from local smelters at distances of 3.6, 3.9, 7 and 9 km, respectively. The dispersion of the Pb contamination plume is possibly driven by the distance from the Beattie smelter. We finally estimated a delay of at least 13 years between atmospheric emissions from the Beattie smelting activities and the time they are recorded by tree rings. Ultimately, this study demonstrates that white cedar tree rings series provide reliable archives of past and present Pb atmospheric contamination.Atmospheric ammonia (NH3) is an alkaline gas and a prominent constituent of the nitrogen cycle that adversely affects ecosystems at higher concentrations. It is a pollutant, which influences all three spheres such as haze formation in the atmosphere, soil acidification in the lithosphere, and eutrophication in water bodies. Atmospheric NH3 reacts with sulfur (SOx) and nitrogen (NOx) oxides to form aerosols, which eventually affect human health and climate. Here, we present the seasonal and inter-annual variability of atmospheric NH3 over India in 2008-2016 using the IASI (Infrared Atmospheric Sounding Interferometer) satellite observations. We find that Indo-Gangetic Plains (IGP) is one of the largest and rapidly growing NH3 hotspots of the world, with a growth rate of +1.2% yr-1 in summer (June-August Kharif season), due to intense agricultural activities and presence of many fertilizer industries there. However, our analyses show insignificant decreasing trends in annual NH3 of about -0.8% yr-1 in all India, about -0.4% yr-1 in IGP, and -1.0% yr-1 in the rest of India. Ammonia is positively correlated with total fertilizer consumption (r = 0.75) and temperature (r = 0.5) since high temperature favors volatilization, and is anti-correlated with total precipitation (r = from -0.2, but -0.8 in the Rabi season October-February) as wet deposition helps removal of atmospheric NH3. This study, henceforth, suggests the need for better fertilization practices and viable strategies to curb emissions, to alleviate the adverse health effects and negative impacts on the ecosystem in the region. On the other hand, the overall decreasing trend in atmospheric NH3 over India shows the positive actions, and commitment to the national missions and action plans to reduce atmospheric pollution and changes in climate.The aim of the present study was to determine the effect of a long-term (113 days) exposure to microplastics on the development and induction of endocrine, geno- and cytotoxic responses in early life stages of sea trout Salmo trutta. Microplastic particles (3000 μm) of three most commonly mass-produced polymers (polystyrene - PS, polyethylene terephthalate - PET and polyethylene - PE) were applied in environmentally realistic concentrations (0.1% of sediment dry weight) in a laboratory experiment imitating the natural environment, typical for sea trout spawning grounds. The exposure of the sea trout, from fertilized eggs to mobile yolk-sac larvae, to microplastics did not affect the hatching success (the survival of embryos), hatching rate and the incubation period. Microplastics of any tested polymer type also had no adverse effect on the larvae survival, growth rate and the rate of yolk sack absorption. Similarly, no changes in frequencies of detected cytotoxicity endpoints compared to the control group were recorded. Exposure to polymer particles induced however the formation of genotoxicity endpoints (nuclear buds, micronuclei and blebbed nuclei cells). The level of total genotoxicity (ΣGentox) in fish larvae erythrocytes increased significantly in the following sequence PS > PET > PE. No significant changes in the whole body corticosterone, dehydrocorticosterone and cortisone concentrations due to exposure to microplastics were recorded, while cortisol was detected in larvae exposed to PS. Our results show that long-term, non-ingestion related exposure to microplastics does not affect development of S. trutta early life stages but may lead to genotoxic responses. PS seems to be the most hazardous among all polymers studied. This is the first study demonstrating non-ingestion related toxicity of microplastics to the early life stages of fish.
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