Notes

Metastasis Features Multiple Roots along with Occurs Early in Tumorigenesis.
DRG payment is beneficial for reduced clinical hospitalization time, cost, and mortality, and improved bed utilization rate and subjective satisfaction, which is worthy of clinical promotion.
To evaluate the therapeutic efficacy and serum inflammatory factors changes of influenza patients received Lianhua Qingwen granule combined with peramivir sodium chloride injection.

The clinical data of 100 influenza patients enrolled in our infirmary from January 2018 to January 2020 were retrospectively analyzed. Among them, 50 patients received eramivir sodium chloride injection (the control group) and 50 patients received Lianhua Qingwen granule plus (the experimental group). The clinical efficacy and serum inflammatory factor, including C-reactive protein (CRP), interleukin (IL)-6, and procalcitonin (PCT) were recorded and compared.

The overall effective rate of the experimental group was significantly higher than that of the control group (96.0% vs. 80%, P=0.014). There was difference in the antipyretic time, sore throat relief time, cough relief time and general ache relief time between the two groups (all
< 0.05). Before treatment, there was no difference in IL-6, CRP, and PCT levels between the two groups (all
> 0.05). After treatment, the IL-6, CRP, and PCT levels were decreased in the two groups, and lower in the experimental group compared with the control group (all
=0.014). The ADRs rate in the experimental group was significantly lower than that of the control group (6.0% vs. 24%, χ
=6.353, P=0.012).

Lianhua Qingwen granule combined with peramivir sodium chloride injection shows a remarkable potency in influenza patients. It can reduce the treatment span and improve the inflammatory factors, which is worthy of clinical promotion and application.
Lianhua Qingwen granule combined with peramivir sodium chloride injection shows a remarkable potency in influenza patients. It can reduce the treatment span and improve the inflammatory factors, which is worthy of clinical promotion and application.
To study the management of thrombus during direct coronary intervention in patients with acute myocardial infarction (AMI).

We retrospectively analyzed 332 acute myocardial infarction patients receiving coronary artery intervention in our hospital from May 2017 to May 2019. Among them, 221 patients received thrombus aspiration and 111 patients received thrombus aspiration combined with platelet membrane glycoproteins receptor antagonist. The propensity score matching 11 nearest neighbor matching method was adopted to match 50 cases of the two methods as the control group and the experimental group, respectively. read more The incidence rate of intraoperative and postoperative adverse reactions, the effective rate of treatment, the electrocardiogram (ECG) at 1 h after operation, and the echocardiographic results at 1 week after operation were compared between the two groups.

The incidence rate of adverse reactions in the experimental group was significantly lower than that in the control group, (P<0.05). The incidence rate of postoperative adverse reactions in the two groups did not statistically differ (P>0.05). The effective rate was found to be substantially higher in the experimental group when compared with that of the control group (P<0.05). The ECG 1 h after operation was in favor of the experimental group (P<0.05). The echocardiography results 1 week after operation were not statistically different in the two groups (P>0.05).

Thrombus aspiration combined with receptor antagonist yielded a desirable outcome in direct coronary intervention for AMI, and has a high application value.
Thrombus aspiration combined with receptor antagonist yielded a desirable outcome in direct coronary intervention for AMI, and has a high application value.
To investigate the clinical significance of the expression levels of transient receptor potential vanilloid 5 (TRPV5) and Osteopontin (OPN) biomarkers for the diagnosis of early-stage urinary stones.

A total of 48 calcium-containing kidney stone patients admitted to our hospital between February 2018 and February 2019 were selected as the experimental group in this study, and another 48 age-matched stone-free healthy individuals were selected as the control group, and the expression levels of TRPV5 and OPN biomarkers in the two groups were examined and compared with respect to related indicators.

The urine oxalic acid content of the experimental group was found to be notably higher than the control group, while the citric acid content was lower; we observed higher levels of the 24-hour urine calcium content in the experimental group, while the citric acid/calcium ratio was remarkably lower; 24-hour urine magnesium and phosphorus levels of the two groups showed no marked difference; the mRNA expression levels of TRPV5 and OPN in the kidney tissues of the two groups were statistically different.

The level of TRPV5 in urinary calculi patients was found to be significantly lower, whereas the level of OPN was significantly higher than the normal control, thus TRPV5 and OPN biomarker levels can be used as diagnostic markers for early urinary calculi.
The level of TRPV5 in urinary calculi patients was found to be significantly lower, whereas the level of OPN was significantly higher than the normal control, thus TRPV5 and OPN biomarker levels can be used as diagnostic markers for early urinary calculi.
To explore the relationship between ApoE gene polymorphism and clinical efficacy of statins on lipidemia.

Peripheral venous blood was obtained from 220 patients with hyperlipidemia who were admitted to the outpatient department of our hospital. The potential relationship between ApoE gene polymorphism and clinical effect of statins was analyzed.

In the three isomers (E2, E3, E4) of ApoE, expression level of ApoE protein in ApoE4 gene carriers was significantly different from that in E2 or E3 gene carriers (both P<0.05). At the same time, both the decrease rate of total cholesterol (TC) in blood lipid and low density lipoprotein cholesterol (LDL-C) and the rise rate of high density lipoprotein cholesterol (HDL-C) in ApoE4 carriers after taking statins were much lower than those in non-ApoE4 patients (P<0.05).

ApoE gene polymorphism is associated with hyperlipidemia and has certain influence on the clinical efficacy of statins in treatment of hyperlipidemia.
ApoE gene polymorphism is associated with hyperlipidemia and has certain influence on the clinical efficacy of statins in treatment of hyperlipidemia.
Our aim was to explore the clinical effect of warm needle penetration in treating knee osteoarthritis.

We randomly divided 118 patients with knee osteoarthritis into the observation group (n=59) and the control group (n=59). The observation group was treated with warm needle penetration combined with western medicine therapy, and the control group was only given western medicine therapy. The clinical effective rate, Visual analogue scale pain score, knee joint score, Western Ontario and McMaster Universities osteoarthritis index and subjective satisfaction were observed and compared between the two groups.

The clinical effective rate, knee joint score and subjective satisfaction rate were higher (all P<0.05), while the Visual analogue scale pain score and Western Ontario and McMaster Universities osteoarthritis indices score were lower in the observation group than in the control group (both P<0.05).

Warm needle penetration can ameliorate the efficiency of treatment, reduce pain, and improve the range of knee joint motion and subjective satisfaction of patients with knee osteoarthritis.
Warm needle penetration can ameliorate the efficiency of treatment, reduce pain, and improve the range of knee joint motion and subjective satisfaction of patients with knee osteoarthritis.
To explore the effect of traction combined with paraffinotherapy on lumbar function in patients with lumbar disc herniation (LDH).

100 LDH patients treated in our hospital (from April 2018 to April 2020) were enrolled and randomized into a control group and experimentalexperimental group, with 50 patients each. The control group adopted traction, and the experimentalexperimental group adopted traction combined with paraffinotherapy. Pain symptoms, lumbar function, range of motion (ROM) and isometric muscle strength (IMS) of lumbodorsal muscle, quality of life, and clinical efficacy were compared before and after treatment.

① After treatment, the effectiveness rate of 96% in the experimental group was higher than the 84% in the control group (P=0.046). ② Visual analogue scale (VAS) score in both groups after treatment was lower than that before treatment, and the experimental group was lower compared with controls (P < 0.05). ③ ROM and IMS of lumbodorsal muscle in both groups after treatment were higher than those before treatment, and the experimental group was higher compared with controls (P < 0.05). ④ The Japanese Orthopaedic Association (M-JOA score) and Oswestry disability index (ODI) in both groups after treatment were lower than those before treatment, and the experimental group was lower compared to controls (P < 0.05). ⑤ After treatment, the life quality indexes of both groups were higher than those before treatment, and the experimental group was higher compared to controls (P < 0.05).

The treatment of traction combined with paraffinotherapy for LDH patients has significant therapeutic efficacy, and can alleviate lumbocrural pain, improve lumbar function and life quality, and is worthy of application.
The treatment of traction combined with paraffinotherapy for LDH patients has significant therapeutic efficacy, and can alleviate lumbocrural pain, improve lumbar function and life quality, and is worthy of application.
To study the curative effect of the traditional Chinese medicine (TCM) Shashen Maidong Decoction in treating lung cancer cachexia based on the cancer toxicity theory, and analyze its influence on patients' serum tumor necrosis factor-α (TNF-α) and interleukin 6 (IL-6).

From January 2018 to January 2019, 104 patients with primary lung cancer cachexia diagnosed and treated in our hospital's oncology department were selected and randomly divided into experimental group and control group, with 52 cases in each group. The control group received routine treatment and nutritional support, while the experimental group received Shashen Maidong Decoction plus. Indexes were compared and analyzed before and after 4 weeks of treatment, including TCM syndrome score, Patient-Generated Subjective Global Assessment (PG-SGA) score, Karnofsky score (KPS), albumin, prealbumin, TNF-α and IL-6 levels.

(1) After treatment, both groups' PG-SGA score, KPS score and TCM syndrome score were better than those before treatment (P &efinite therapeutic effects and important clinical values. It can effectively alleviate patients' symptoms, improve nutritional status, and reduce body's inflammatory response.
To investigate the changes of triacylglycerol and inflammatory factors after hypertriglyceridemia acute pancreatitis (HTG-AP) dialysis during pregnancy and to analyze the nursing strategies.

50 patients treated with HTG-AP dialysis in our hospital from February 2017 to June 2019 were selected. The patient's vital signs, triglyceride (TG), total cholesterol (TC), TG and TC decline rates before treatment, 1, 3, and 5 days after treatment and inflammatory factors [tumor necrosis factor-α (TNF-α), Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Interleukin-10 (IL-10) level changes] were measured, as well as the acute physiological and chronic health evaluation II (APACHEII), multiple organ dysfunction syndromes (MODS), systemic inflammatory response syndrome (SIRS) and maternal treatment outcomes.

There was no significant change in body temperature before and after treatment (P>0.05); The heart rate, WBC, CRP before and after treatment were statistically different (P<0.05); Compared with before treatment, serum levels of TG and TC significantly decreased after treatment, and the rate of decrease was significantly increased (P<0.
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