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Classical theories of attention posit that integration of features into object representation (or feature binding) requires engagement of focused attention. Studies challenging this idea have demonstrated that feature binding can happen outside of the focus of attention for familiar objects, as well as for arbitrary color-orientation conjunctions. Detection performance for arbitrary feature conjunction improves with training, suggesting a potential role of perceptual learning mechanisms in the integration of features, a process called "binding-learning". In the present study, we investigate whether stimulus variability and task relevance, two critical determinants of visual perceptual learning, also modulate binding-learning. Transfer of learning in a visual search task to a pre-exposed color-orientation conjunction was assessed under conditions of varying stimulus variability and task relevance. We found transfer of learning for the pre-exposed feature conjunctions that were trained with high variability (Experiment 1). Transfer of learning was not observed when the conjunction was rendered task-irrelevant during training due to pop-out targets (Experiment 2). Our findings show that feature binding is determined by principles of perceptual learning, and they support the idea that functions traditionally attributed to goal-driven attention can be grounded in the learning of the statistical structure of the environment.The size congruity effect in a numerical Stroop task shows that magnitude judgments of two numbers are faster and more accurate when the numerically larger number also appears in a physically larger size, indicating the interaction between numerical and physical magnitudes. It has recently been suggested that spatial shifts of attention between the two numbers may contribute to the size congruity effect. However, a complete line of evidence for the attentional attribution to the size congruity effect remains to be established. Therefore, the present study aimed to provide further demonstrations for the idea that spatial shifts of attention contribute to the size congruity effect during magnitude judgments regarding either the numerical or physical dimension of two numbers. Participants were sequentially or simultaneously presented with a pair of single-digit Arabic numbers whose numerical and physical magnitudes varied independently. They were instructed to perform a magnitude judgment regarding the numerical value or physical size of the paired numbers. Across three experiments, we consistently found that the size congruity effect was reduced or eliminated when number pairs were presented sequentially compared to when they were presented simultaneously. Because in the sequential presentation mode the paired numbers were successively presented at central fixation and therefore spatial attention shifts should be completely precluded by the central presentation of number stimuli, the present findings support the notion that spatial shifts of attention between numbers in the simultaneous presentation mode play an important role in generating the size congruity effect for both numerical and physical tasks.DICER1, a member of the ribonuclease III family, is involved in the biogenesis of microRNAs and, hence, it influences gene expression regulation. DICER1 germline (associated with the inherited DICER1 syndrome) or somatic mutations have been linked to tumorigenesis in histogenetically diverse benign and malignant neoplasms in different organs including pleuropulmonary blastoma, cystic nephroma, embryonal rhabdomyosarcoma, nasal chondromesenchymal hamartoma, poorly differentiated thyroid carcinoma, thyroblastoma, intracranial sarcoma and gonadal Sertoli-Leydig cell tumors in addition to others. Moreover, rare botryoid (giant) fibroepithelial polyps may harbor this mutation. Herein, we describe the first reported case of a DICER1-mutated botryoid fibroepithelial polyp occurring within the parotid duct of a 65-year-old female who has no other features or family history of the DICER1 syndrome. Based on its distinctive morphology, we tested this lesion specifically for DICER1 mutations and confirmed the presence of a pathogenic DICER1 variant with a low allele frequency, consistent with a somatic mutation.Adenoid ameloblastoma is a hybrid odontogenic tumour showing histopathological features of both ameloblastoma and adenomatoid odontogenic tumour (AOT), with approximately 40 cases reported in the literature. The aims of the report are to illustrate the diagnostic challenges of adenoid ameloblastoma using three new cases and to analyze evidence in literature to consider adenoid ameloblastoma as a new sub type of ameloblastoma. A literature review was performed with the key words-adenoid ameloblastoma, hybrid/composite odontogenic tumours, hybrid ameloblastoma and adenomatoid odontogenic tumour, ameloblastoma with inductive changes, dentinoid and dentinoma to select the cases compatible with the diagnosis of adenoid ameloblastoma. Out of the 40 cases reported in literature, 31 cases with sufficient information and 3 new cases were analyzed. EGFR inhibitor Out of the 34 adenoid ameloblastomas majority of tumours (76.5%) occurred in adults with age ranging from 25 to 55 years. Slight female predilection with a malefemale ratio astoma as a sub type of ameloblastoma in the next revision of the WHO odontogenic tumour classification.Kimura disease (KD) is a rare inflammatory disorder which involves the head and neck. Due to its rarity and various findings, definitive diagnosis can be difficult to ascertain. Kimura disease is distinguished from other conditions, including angiolymphoid hyperplasia, by histopathological features including follicular hyperplasia, reactive germinal centers, abundant eosinophilia, eosinophilic microabscesses, preserved nodal architecture, Warthin-Finkeldy polykaryocytes, and capsular fibrosis. Herein, we describe the clinical presentation, pathology, and diagnosis of a single case of a 39-year-old treated at an academic center in Texas.People can make judgments about statistical properties of visual features within groups of objects, such as the average size, size variability, or numerosity of circles. Emerging from recent work is the view that these kinds of visual estimations, collectively dubbed ensemble perception, rely on independent abilities that are specific to the statistical property being estimated (mean, variance, range, numerosity). Here we revisit evidence for the claim that different statistical judgments (i.e., average and variability) for the same object feature are based on independent abilities. We tested a large sample of people, using a pre-registered open-ended sequential design to avoid ending up with weak evidence. We estimated the shared variance in ability across different ensemble judgments, with common constraints for the different tasks. We found that the abilities to judge the average size and the size variability for an array of circles are positively correlated, even after controlling for the ability to discriminate the size of single circles.
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