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Carboxyhemoglobin quantities in kids throughout extracorporeal membrane layer oxygenation assist: a new retrospective examine.
Business process modeling aims to construct digital representations of processes being executed in the company. However, models derived from the event logs of their execution tend to overcomplicate the desired representation, making them difficult to apply. The most accurate recovery of the business process model requires a comprehensive study of the various artifacts stored in the company's information system. This paper, however, aims to explore the possibility to automatically obtain the most accurate model of business process, using mutual optimization of models recovered from a set of event logs. Further, the obtained models are executed in multi-agent simulation model of company, and the resulting event logs are examined to determine patterns that are specific to distinct employees and those that generally characterize business process.Today pneumonia is one of the main problems of all countries around the world. This disease can lead to early disability, serious complications, and severe cases of high probabilities of lethal outcomes. A big part of cases of pneumonia are complications of COVID-19 disease. This type of pneumonia differs from ordinary pneumonia in symptoms, clinical course, and severity of complications. For optimal treatment of disease, humans need to study specific features of providing 19 pneumonia in comparison with well-studied ordinary pneumonia. In this article, the authors propose a new approach to identifying these specific features. This method is based on creating dynamic disease models for COVID and non-COVID pneumonia based on Bayesian Network design and Hidden Markov Model architecture and their comparison. We build models using real hospital data. We created a model for automatically identifying the type of pneumonia (COVID-19 or ordinary pneumonia) without special COVID tests. And we created dynamic models for simulation future development of both types of pneumonia. All created models showed high quality. Therefore, they can be used as part of decision support systems for medical specialists who work with pneumonia patients.In this paper, we present a framework, which aims at facilitating the choice of the best strategy related to the treatment of periprosthetic joint infection (PJI). The framework includes two models a detailed non-Markovian model based on the decision tree approach, and a general Markov model, which captures the most essential states of a patient under treatment. The application of the framework is demonstrated on the dataset provided by Russian Scientific Research Institute of Traumatology and Orthopedics "R.R. Vreden", which contains records of patients with PJI occurred after total hip arthroplasty. The methods of cost-effectiveness analysis of treatment strategies and forecasting of individual treatment outcomes depending on the selected strategy are discussed.The relevance of this study lies in improvement of machine learning models understanding. We present a method for interpreting clustering results and apply it to the case of clinical pathways modeling. This method is based on statistical inference and allows to get the description of the clusters, determining the influence of a particular feature on the difference between them. Based on the proposed approach, it is possible to determine the characteristic features for each cluster. Finally, we compare the method with the Bayesian inference explanation and with the interpretation of medical experts [1].Electronic Medical Records (EMR) contain a lot of valuable data about patients, which is however unstructured. There is a lack of labeled medical text data in Russian and there are no tools for automatic annotation. We present an unsupervised approach to medical data annotation. Morphological and syntactical analyses of initial sentences produce syntactic trees, from which similar subtrees are then grouped by Word2Vec and labeled using dictionaries and Wikidata categories. This method can be used to automatically label EMRs in Russian and proposed methodology can be applied to other languages, which lack resources for automatic labeling and domain vocabularies.This article describes the results of feature extraction from unstructured medical records and prediction of postoperative complications for patients with thoracic aortic aneurysm operations using machine learning algorithms. The datasets from two different medical centers were integrated. Seventy-two features were extracted from Russian unstructured medical records. We formulated 8 target features Mortality, Temporary neurological deficit (TND), Permanent neurological deficit (PND), Prolonged (> 7 days) lung ventilation (LV), Renal replacement therapy (RRT), Bleeding, Myocardial infarction (MI), Multiple organ failure (MOF). XGBoost showed the best performance for most target variables (F-measure 0.74-0.95) which is comparable to recent results in cardiovascular postoperative risks prediction.The global pandemic over the past two years has reset societal agendas by identifying both strengths and weaknesses across all sectors. Focusing in particular on global health delivery, the ability of health care facilities to scale requirements and to meet service demands has detected the need for some national services and organisations to modernise their organisational processes and infrastructures. Core to requirements for modernisation is infrastructure to share information, specifically structural standardised approaches for both operational procedures and terminology services. Navitoclax Problems of data sharing (aka interoperability) is a main obstacle when patients are moving across healthcare facilities or travelling across border countries in cases where emergency treatment is needed. Experts in healthcare service delivery suggest that the best possible way to manage individual care is at home, using remote patient monitoring which ultimately reduces cost burden both for the citizen and service provider. Core to this practice will be advancing digitalisation of health care underpinned with safe integration and access to relevant and timely information. To tackle the data interoperability issue and provide a quality driven continuous flow of information from different health care information systems semantic terminology needs to be provided intact. In this paper we propose and present ContSonto a formal ontology for continuity of care based on ISO 139402015 ContSy and W3C Semantic Web Standards Language OWL (Web Ontology Language). ContSonto has several benefits including semantic interoperability, data harmonization and data linking. It can be use as a base model for data integration for different healthcare information models to generate knowledge graph to support shared care and decision making.Digital information consists of sequences of numbers that are selections. So far, these are defined by context. We can globalize this by using an efficient global pointer (UL) as "context". The article explains new globally identified and defined "Domain Vectors" (DVs) for transporting digital information. They have the structure "UL plus sequence of numbers", where UL is an efficient identifier and global pointer (link) to the unified online definition of the sequence of numbers. Thus, the format of the number sequence and its meaning is defined online. This opens up far-reaching new possibilities for the efficient exchange, comparison and search of information. It can form the basis for a new global framework that improves the reproducibility, search, and exchange of data across systems, borders, and languages.The Coronavirus pandemic has surprised the world and social media was extremely used to express frustrations and development of the cases found. Social media tools, such as Twitter, show a comparable impact with the number of tweets related to COVID-19 indicating remarkable development in a limited ability to focus time. The purpose of this paper is to investigate the impact of Coronavirus on the United States of America (USA) and New Zealand (NZ), and how that is reflected in a sentiment analysis through the examination of American and New Zealand tweets. We have gathered tweets from a March 2020 - August 2020 and used sentiment extraction on the tweets. The major finding of this sentiment extraction is the fact that the overall average sentiment over the 5-month period stayed in a negative range in the USA and NZ. This paper aims to analyze these trends, identify patterns, and determine whether these trends were caused by the COVID-19 pandemic or outside sources. One trend that was analyzed was the spike of COVID-19 results in relation to the number of protests occurring in the USA.In this ongoing fall of the year 2021, many disciplines are frightened by the Covid-19 situation. A generalized sense of Scientific and administrative impotence, - in keeping the pandemic under real control, - is felt widely in Society. In this Invited Lecture the author reminds us of the blows suffered, recalls pertinent elements present in our social organization, browses selected eHealth experiences and proposes an open agenda of actions to allow the eHealth to help the population segments better, and individuals as well.The paper describes some aspects of precision medicine and shows the importance of pharmacokinetics and pharmacodynamics for the therapeutic drug monitoring and model-informed precision dosing. A key element in the design of the pharmacokinetics and pharmacodynamics (PKPD) models is relevant literature search that represents an essential step in the procurement and validation of a new drug. Available search engine resources do not offer specific functionalities that are required for efficient and relevant search in reliable literature sources. We present a prototype of such an intelligent search engine and show its results on real project data.pHealth is a data (personal health information) driven approach that use communication networks and platforms as technical base. Often it' services take place in distributed multi-stakeholder environment. Typical pHealth services for the user are personalized information and recommendations how to manage specific health problems and how to behave healthy (prevention). The rapid development of micro- and nano-sensor technology and signal processing makes it possible for pHealth service provider to collect wide spectrum of personal health related information from vital signs to emotions and health behaviors. This development raises big privacy and trust challenges especially because in pHealth similarly to eCommerce and Internet shopping it is commonly expected that the user automatically trust in service provider and used information systems. Unfortunately, this is a wrong assumption because in pHealth's digital environment it almost impossible for the service user to know to whom to trust, and what the actual level of information privacy is. Therefore, the service user needs tools to evaluate privacy and trust of the service provider and information system used. In this paper, the authors propose a solution for privacy and trust as results of their antecedents, and for the use of computational privacy and trust. To answer the question, which antecedents to use, two literature reviews are performed and 27 privacy and 58 trust attributes suitable for pHealth are found. A proposal how to select a subset of antecedents for real life use is also provided.
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