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Chronic obstructive pulmonary disease is associated with an uncertain trajectory, which challenges prognostication and means that most patients are not involved in advance care planning and do not receive palliative and end-of-life care.
To understand the preferences of patients with chronic obstructive pulmonary disease for discussions about palliative and advance care planning with clinicians.
Semi-structured interviews were conducted with patients with chronic obstructive pulmonary disease. Data analysis was guided by principles of interpretative phenomenological analysis, of which symbolic interactionism and interpretation principles were employed throughout.
A total of 33 British patients with chronic obstructive pulmonary disease at different stages of their disease trajectory were recruited.
Patients preferred to discuss palliative care with clinicians they perceived had greater levels of competency and authority in care and with whom they had an established relationship, usually a specialistit patients from initiating early discussions with clinicians, so palliative care conversations should be initiated by respiratory-expert clinicians who know the patient well. After a sudden deterioration in the patient's condition may be a suitable time.
E-cigarette use is increasing in popularity for high school students (Singh etal., 2016) and may be accompanied by negative health outcomes (Rankin etal., 2019). Students who identify as sexual minority (lesbian, gay, bisexual, or queer/questioning) may be at an increased risk of bullying victimization and substance use due to their sexual identity (Caputi, 2018).
This study explored the relationship between bullying in school and cyberbullying (i.e. bullying through social media) victimization with past 30-day e-cigarette use for sexual minority youths, an at-risk group for victimization and its negative consequences.
The Youth Risk Behavioral Survey was utilized to study a sample of sexual minority high school students (
= 2302; 69.4% female). Three models were utilized to examine whether bullying in school or cyberbullying victimization were related to e-cigarette use after controlling only for demographics in the demographics model, and then the use of other substances in the substance use modelt separately. Cyberbullying victimization was significantly related to combined cigarette and e-cigarette use. Conclusions/Importance These findings suggest that sexual minority students who report cyberbullying victimization may use cigarette products more than their noncyberbullied peers. Cyberbullying prevention and interventions should continue to be targeted in schools, especially for sexual minority youths.
Gliomatosis peritonei (GP) is characterized by widespread implants of mature glial tissue in the peritoneum. It is most often associated with immature or mature ovarian teratomas.
A 6-month old infant developed isolated gliomatosis involving the tunica vaginalis following excision of an immature sacrococcygeal teratoma in the neonatal period.
Tunica vaginalis gliomatosis can occur in the setting of a retroperitoneal extragonadal congenital immature teratoma.
Gliomatosis peritonei (GP) is characterized by widespread implants of mature glial tissue in the peritoneum. It is most often associated with immature or mature ovarian teratomas. Case Report A 6-month old infant developed isolated gliomatosis involving the tunica vaginalis following excision of an immature sacrococcygeal teratoma in the neonatal period. Conclusion Tunica vaginalis gliomatosis can occur in the setting of a retroperitoneal extragonadal congenital immature teratoma.
This study aims to assess the effectiveness of the non-ablative photothermal erbium laser (ErYAG laser) for managing anterior and/or posterior vaginal compartment prolapse.
A randomized, single-blind, 11 trial was performed comparing ErYAG laser treatment to watchful waiting in postmenopausal women with symptomatic cystocele and/or rectocele stage 2 or 3 who opted to undergo surgery due to bothersome prolapse symptoms. Three ErYAG laser treatments at monthly intervals were applied for the ErYAG laser group, while there was no treatment for the watchful-waiting group. The primary outcome was the proportion of patients with stage 0 or 1 following laser treatment, while secondary outcomes included the Pelvic Organ Prolapse Quantification System (POP-Q points), Pelvic Floor Distress Inventory Questionnaire short-form, Pelvic Floor Impact Questionnaire short-form, and Patients Global Impression of Improvement (PGI-I). All outcomes were evaluated at baseline and 4 months post baseline.
Thirty women (15 vs. 15) were eligible to be included. No participants (0%) in either group had POP-Q stage 0 or 1 at 4 months. Moreover, no change was present in the secondary outcomes. check details In the PGI-I, 2/15 (14%) and 0/15 (0%) participants declared much better/very much better in the laser and watchful-waiting group, respectively.
The findings of this study do not support use of the intravaginal ErYAG laser for treatment of the anterior/posterior vaginal wall.
NCT03714607.
The findings of this study do not support use of the intravaginal ErYAG laser for treatment of the anterior/posterior vaginal wall. Clinical trial identification number NCT03714607.
To describe the presence of outer retinal tubulations (ORTs) in a patient diagnosed with maternally inherited diabetes and deafness (MIDD) - associated macular dystrophy.
The patient underwent clinical examination assessing best-corrected visual acuity (BCVA), anterior segment evaluation and fundoscopy followed by optical coherence tomography (OCT). Audiological evaluation was also performed for the accurate diagnosis of MIDD.
A 57-year-old diabetic patient with mildly affected BCVA, macular dystrophy and severe neurosensory hearing loss was diagnosed with MIDD. Examination with OCT revealed the central loss of photoreceptors and the presence of ORTs in close proximity to the fovea. Regular follow-up seven months after her initial visit showed no alterations in the clinical and imaging status of the patient. In the context of family screening, the patient's sister presented with the diagnosis of pre-diabetes and a moderate sensorineural hearing loss, while fundus examination and OCT revealed no significant pathology.
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