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Glucagon-like Peptide-1 Receptor Agonists as well as Cardioprotective Benefit in Patients together with Diabetes type 2 With no Base line Metformin: A deliberate Review and Update Meta-analysis.
The present study is designed to test the effectiveness of two positive psychological micro-interventions ("use your resources" and "count your blessings") aimed at improving the combination of work and family roles. Based on the Transactional Model of Stress (TMS), the Conservation of Resources (COR) Theory and the Work-Home Resources (WH-R) Model, it was expected that the interventions would result in a more positive cognitive appraisal of combining both roles as well as in less work-to-family and family-to-work conflict and more work-to-family and family-to-work enrichment. The hypotheses were tested in a field experiment with three conditions and three measurement waves. In total, 218 working mothers participated in the study. The "use your resources" intervention appeared effective in sorting positive effects on the work-family outcome variables. Participating in the "count your blessing" micro-intervention did not result in a better (appraisal of the) combination of work and family roles. Moreover, for generating positive effects it was important that the participants performed the exercises on a regular basis the more days women performed the exercise, the stronger the effects. The implications of our findings for future interventions to improve work-family role combining are discussed. Copyright © 2020 Peeters, van Steenbergen and Ybema.The evolution of the human brain and visual system is widely believed to have been shaped by the need to process and make sense out of expressive information, particularly via the face. We are so attuned to expressive information in the face that it informs even stable trait inferences (e.g., Knutson, 1996) through a process we refer to here as the face-specific fundamental attribution error (Albohn et al., 2019). We even derive highly consistent beliefs about the emotional lives of others based on emotion-resembling facial appearance (e.g., low versus high brows, big versus small eyes, etc.) in faces we know are completely devoid of overt expression (i.e., emotion overgeneralization effect see Zebrowitz et al., 2010). The present studies extend these insights to better understand lay beliefs about older and younger adults' emotion dispositions and their impact on behavioral outcomes. In Study 1, we found that older versus younger faces objectively have more negative emotion-resembling cues in the face (using computer vision), and that raters likewise attribute more negative emotional dispositions to older versus younger adults based just on neutral facial appearance (see too Adams et al., 2016). In Study 2, we found that people appear to encode these negative emotional appearance cues in memory more so for older than younger adult faces. Finally, in Study 3 we exam downstream behavioral consequences of these negative attributions, showing that observers' avoidance of older versus younger faces is mediated by emotion-resembling facial appearance. Copyright © 2020 Albohn and Adams.This article, corresponding to a part of the restitution of a financed international research project between France, Brazil, Canada, Italy and Belgium, aims to offer a modelisation and qualitative evaluation of mediation care settings based on an original methodological tool that involves identifying the typical games at the foundations of creativity, following a multidisciplinary perspective. Therapeutic mediations are settings or devices organized around a "pliable medium," often artistic, like painting, modeling, writing and theater, which are very widespread in institutional practices, both in France and abroad. The scientific objectives of this research consist in a multi-disciplinary exploration (anthropology, criminology, neuroscience, clinical psychology) of the process of creative symbolization understood as a process of transformation involving play. According to this orientation, play can be defined as a psychic process whereby a subjective experience can be explored with pleasure, and consequentl settings, with a convergence of the different disciplines emphasizing the pertinence of this model. The scientific impact of this research overlaps with its societal impact, through the development of innovative tools for evaluating therapeutic mediations, in order to take account of the evolution of the different forms of social expression of psychic suffering. Copyright © 2020 Brun, Brunet, Cerclet, Masson, Ravit, Tassin, Zornig, Zurlo, Guénoun, Missonnier, Di Rocco, Mitsopoulou, Jacquet, Jung and Roussillon.We propose a new method that balances attribute coverage for short-length cognitive diagnostic computerized adaptive testing (CD-CAT). The new method uses the attribute discrimination index (ADI-based method) instead of the number of items that measure each attribute [modified global discrimination index (MGDI)-based method] to balance the attribute coverage. Therefore, the information that each attribute provides can be captured. The purpose of the simulation study was to evaluate the performance of the new method, and the results showed the following (a) Compared with uncontrolled attribute-balance coverage method, the new method produced a higher mastery pattern correct classification rate (PCCR) and attribute correct classification rate (ACCR) with both the posterior-weighted Kullback-Leibler (PWKL) and the modified PWKL (MPWKL) item selection method. (b) Equalization of ACCR (E-ACCR) based on the ADI-based method leads to better results, followed by the MGDI-based method. The uncontrolled method leads to the worst results regardless of item selection methods. (c) Both the ADI-based and MGDI-based methods produced acceptable examinee qualification rates, regardless of item selection methods, although they were relatively low for the uncontrolled condition.Background Cocaine is a psychostimulant drug used as performance enhancer throughout history. The prolonged use of cocaine is associated with addiction and a broad range of cognitive deficits. Currently, there are no medications proven to be effective for cocaine-use disorder (CocUD). Previous preliminary clinical work suggests some benefit from repetitive transcranial magnetic stimulation (rTMS) stimulating the prefrontal cortex (PFC), involved in inhibitory cognitive control, decision-making and attention. All published studies to date have been limited by small sample sizes and short follow-up times. Methods This is a retrospective observational study of 284 outpatients (of whom 268 were men) meeting DSM-5 criteria for CocUD. At treatment entry, most were using cocaine every day or several times per week. All patients underwent 3 months of rTMS and were followed for up to 2 years, 8 months. Self-report, reports by family or significant others and regular urine screens were used to assess drug use. CP-673451 in vivo Results Median time to the first lapse (resumption of cocaine use) since the beginning of treatment was 91 days.
Website: https://www.selleckchem.com/products/CP-673451.html
     
 
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