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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are often described as a focus on the practical aspects of designing a study that include the recruitment process and consent, adhering and the use of routinely available equipment.

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Pragmatic is a software company, offers a variety of casino games on online gambling platforms. Its iGaming solutions are utilized by the top operators and casinos with a physical location. The company offers front-end website design tools, analysis and promotions, marketing, security, payment systems, customer support and bug reporting. Additionally, the company offers its players a safe and secure environment with high-quality graphics as well as games.

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A pragmatic study that involves various investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is required for pragmatic trials to be valid, and it also reduces bias in the results. However excessive heterogeneity could result in problems with the design of the trial.

Pragmatic Play is one of the biggest players on the live casino market, offers various classic table games like Blackjack and Roulette. Pragmatic Play's live studios in Romania and Malta offer a real-life gaming experience for its customers and offer an extensive selection of virtual betting options. The company also offers a variety of game shows that make online gambling more exciting and interactive. Some of these shows are broadcast live, while others feature famous personalities in the field.

Mobile compatibility

Pragmatic Play is a relatively new player in the online casino industry however, it has made a name for itself with its mobile-friendly slots. Their games are optimized for mobile devices and are powered by HTML5 technology. They are also certified and regulated by trusted gaming authorities, ensuring fairness and transparency. This is a great signal for players since it means the games have been thoroughly tested and verified in order to ensure the randomness and unbiased results of every game.

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Legality

Pragmatic Play is renowned for its top-quality games and also for providing an outstanding user experience. The software is available on mobile devices as well as in various languages. It has established itself as one of the leading gaming platforms in the casino industry despite its relative infancy. Wolves is one of the most recent releases which is a five-reel slot machine with a healthy RTP and stunning graphics. Other notable games include Wolf Gold and Chilli Heat.

The aim of pragmatic trials is to simulate real-life scenarios and gain the highest level of validity externally. They are usually commissioned by policymakers and practitioners to help guide their decisions. They also provide a useful way to identify the causality between the intervention and its effects. They should, however, not be used to replace explanatory studies.

The pragmatism idea is controversial and there are doubts about whether pragmatic trials should replace tests for explanations or if they should serve as an alternative to them. Schwartz and Lellouch1 suggested a distinction between explanatory studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the decision-making process for policy and practice. They also suggested a framework known as PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a practical study, including recruitment, design, implementation of the intervention, and follow-up.

There is a growing trend in the number of pragmatic trials that are published. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are highlighted in red on Figure 2. This indicates that the health sciences community is becoming increasingly sensitized to the issue of pragmatic thinking. It is important to note, however, that the majority of studies were conducted in primary-care settings.

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