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Shaping Potential Doctors' Heads: Effects of Biological along with Social Versions about Medical Students' Views on Depressive disorders.
The clinical variants of subacute thyroiditis in COVID-19 are diverse and have not been fully evaluated. In this regard, it can be concluded that the true incidence of subacute thyroiditis in COVID-19 is much greater, since it is masked by severe lesions of other organs.It has been established that the eosinophilic phenotype of COPD is separate phenotype of the disease. The results of some studies demonstrate the possibility that may presence a phenotype with an increased level of eosinophil activity. To study the relationship between the blood ECP level and the characteristics of the course of COPD, we examined 161 patients with COPD aged from 40 to 70 years old, smoking index> 10 pack-years, no history of atopy, total blood Ig E 100 cells/μL in combination with ≥2 exacerbations of moderate or severe severity during the year, but not with stratification by the level of blood eosinophils (≥300 cells/μL, less then 300 cells/μL). It has been shown that an increase in ECP in accordance with moderate and severe exacerbations is a more reliable markers of the development of the eosinophilic phenotype in patients with COPD.The purpose of the study was to search for a correlation between FEV1 and the possible predictors that determine disease progression and lung function deterioration in COPD patients. The research was conducted at N. Kipshidze Central University Clinic. 78 COPD patients participated in it. Spirometry was used to diagnose the participants and GOLD guidelines for COPD were applied to estimate stages of disease severity. Multiple regression analysis were conducted in order to estimate severity of COPD and its risk factors. The research revealed statistically significant correlation between lung function deterioration and the factors such as age, BMI, duration of COPD, hospitalization frequency due to COPD exacerbation based on the patient's anamnesis and self-assessment questionnaire for dyspnea. It can be considered statistically significant that early diagnosing of COPD and therefore timely and adequate treatment, prevention of disease exacerbation and adherence to a healthy lifestyle notably determines severity of the disease and its prognosis. Statistically significant correlation that was revealed between FEV1 and dyspnea self-assessment questionnaire increases the clinical value of this questionnaire in estimating COPD severity.The aim of our study was to study prevalence and clinical importance of Hyperuricemia (HU) in patients with heart failure (HF). 126 patients with HF were involved in a study. Main group included 75 patients with HF and HU. 51 patients with HF without HU were included in the control group. All patients underwent to a standardized clinical evaluation, including physical examination, determination of NYHA class and laboratory studies; namely, full blood count, serum uric acid, creatinine and ferritin. Assessment of exercise capacity was performed using a 6-min walk test. Echocardiographic assessment included interventricular septum thickness, left ventricular systolic and diastolic dimensions, left ventricular diastolic function, posterior wall thickness, left ventricular mass index and LVEF. Patients with HU had higher prevalence of diabetes mellitus than patients without HU. Patients with HU had significantly lower LVEF (38.2±7.0 and 44.5±5.1; respectively. read more P less then 0.05). No differences were recorded for b and independent association with reduced exercise capacity, it is highly recommended to define HU level in all the patients with chronic heart failure to avoid future complications.The aim was to study the effects of non-functional overreaching and overtraining on responses of biomarkers of the skeletal muscle cell (CK-NAC) and cardiomyocyte injury (cTnI and CK-MB) and their use in monitoring OTS. In 43 athletes with non-functional overreaching (NFO)/overtraining syndrome (OTS) and 40 athletes without NFO/OTS -control athletes (CA) off-season measurements of creatine kinaze (CK-NAC and CK-MB) were performed, followed by peak-season evaluation of the dynamic of CK-NAC, CK-MB and cardiac troponin I (cTnI) changes. CK and cTnI levels were obtained 24 hrs before the strenuous exercise appropriate to the sport-specific peak-season intensity, immediately after completion of the work-load, after 6, 48, and 72hrs. Baseline and post-exercise clinical assessment and echocardiography were performed in 6 and 48 hrs after strenuous session. Similar rising trend of CK-NAC, CK-MB, and cTnI levels was observed immediately after exercise, reaching peak values after 6 hours in all athletes, though, signile and transient increase of the CK-MB and cTnI, without irreversible pathophysiological and clinical consequences, suggesting mostly benign cardiac involvement, though amplified by existent oxidative stress in athletes with OTS. Monitoring responses via alterations of biochemical parameters can be helpful to guide athletic training, and prevent OTS or interrupt NFO to OTS progression.132 women after facial contouring on terms from 2 weeks to 15 years after filler injection were examined by sonography (US). They had complaints of the edema, hypercorrection, asymmetry, discomfort and anxiety about the excess of the terms that filler had spent into the soft tissues. HA fillers were injected in 111 cases (84.1%), silicon agents - in 13 cases (9.8%), CaHA - in 6 (4.5%), PMMA - on 1 (0.8%) and one patient have had non-hyalouronic filler with unknown origin (0.8%). According to the US data, nasolacrimal and palpebromar fissures were the most common location of fillers or the echo signs of fibrotic changes in the projection of their injection - 54 patients, just like the lips region and nasolabial folds - 52 cases. The US of the skin and the soft tissues of the face and neck region prescribed to the patients in order to carry out the differential diagnosis of complaints' causes, to determine the treatment tactics and for planning cosmetic procedures.The aim - in the given research, the difficulties in interpreting the study results of oxidative homeostasis of oral fluid are analyzed. Changes in the total antioxidant activity of blood and saliva can be multidirectional - an increase or decrease in the oral fluid indicator and a reduction in the parameter of blood plasma can be recorded. To resolve the emerging difficulties, there was proposed a parallel assessment of the dynamics of changes in the total antioxidant activity of blood plasma and oral fluid in the patients of 4 groups with nosological forms of fundamentally different in the distribution and localization of the pathological process, which include phlegmons of the maxillofacial region, partial absence of teeth, type 2 diabetes mellitus and the pelvic inflammatory diseases. As a result of the conducted studies, it was shown that a simultaneous decrease in the total antioxidant activity of blood plasma and oral fluid was attributable to the chronic long-term somatic diseases of a systemic characitation only to the dentoalveolar system's tissues and elements. As an example of such a situation, the patients with phlegmon of the maxillofacial region or patients with partial absence of teeth can be cited.Excessive tooth wear is currently one of the main problems of oral health. Excessive tooth wear affects both function and aesthetics. Teeth with excessive tooth wear cannot be effectively used for biting and chewing food. Treating excessive tooth wear is complex and time consuming. Studies on increasing the effectiveness of treatment of such patients are relevant. The study involved 60 people with a significant degree of excessive tooth wear and a decrease in the height of the bite. We examined patients using measurements of the electromyographic (EMG) activity of mm.masseter and temporalis. The subjects were divided into two groups - in the first group (30 people), the maxillofacial system was prepared for further prosthetics by wearing a removable dental splint-teethguard, in the second group (30 people) we used both removable splint-teethguards and transcutaneous electrical nerve stimulation (TENS). In both groups, an electromyographic study of mm.masseter and temporalis was performed after 1 week, 1 and 2 months of treatment. In patients with excessive tooth wear and a significant decrease in bite height, our method of preparation for orthopedic treatment contributed to a more rapid normalization of mm.masseter and temporalis functions. The results indicate a pronounced positive effect of the use of removable teeth guard and TENS on the normalization of the bioelectric activity of the masticatory muscles in the preparation of patients for orthopedic treatment of excessive tooth wear.Surgically assisted rapid maxillary expansion (SARME) is a common technique developed to treat skeletally mature patients with transverse maxillary deficiency. Although SARME is supposed to be a relatively safe procedure, it is not completely free of complications. The purpose of this study was to reveal the most typical postoperative SARME complications. Retrospective evaluation of the clinical cases of 665 patients (247 males and 418 females, mean age 25,3 years) with the diagnosis of maxillary transverse deficiency, who underwent SARME in period between 2012 and 2017 at the Clinical Center of Maxillofacial, Plastic Surgery and Dentistry, Moscow. According to the results of the research, the most typical complications of SARME are paresthesia of the infraorbital nerve branches and nasopalatine nerve (198/665), distraction device dislocation (61/665), inflammation in the distraction device area (57/665), insufficient expansion of the maxilla (42/665), asymmetric expansion (27/665). The number of complications revealed indicates that SARME is an operation associated with the risks of postoperative complications. Careful treatment planning, following the operation protocol and performing the minimally invasive access can help to avoid the majority of complications.Chronic generalized parodontitis is one of the most prevalent disorders among diseases of oral cavity, making the search for optimal treatment modalities of this disorder one of the mostressing matters to this day.  The purpose of this study was to assess outcomes of conventional therapy and secondary prevention of chronic generalized parodontitis with in combination with use of laser therapy and antioxidant drug treatment.  The study is presented as a joint multi-site investigation conducted by the group of authors from St. Petersburg and Saransk medical teaching and clinical institutions. The aim of the study was to improve the treatment and secondary prevention of chronic generalized parodontitis based on a pathogenetically substantiated scheme of laser and antioxidant therapy.  The total of 98 patients (31 male and 67 female) aged 30-50 years) with the 3 to 10 year history of moderate chronic generalized parodontitis were selected for the prospective study.  All patients were approximately equally divided into three groups according to the received treatment regimens conventional treatment, laser therapy, and laser therapy with antioxidant medication. Several clinical indices were utilized for parodontal tissue assessment (PMA, SBI, AP), resistance of gingival capillary bed, osteal resorption. The lipid peroxide oxidation was determined by MDA, Fe2+ MDA  and phospholipase A2.  Additional implementation of laser and metabolic therapies sufficiently increases efficacy of conventional therapy and improves secondary prevention of chronic parodontitis. A marked decrease in structural-functional deviations and apparent recovery of microcirculatory vascular bed of parodontal tissue has been achieved. .
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