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Usefulness regarding ultrasound-accelerated vs . standard catheter-directed thrombolysis in management of lower extremity heavy venous thrombosis: A new process regarding systematic review and meta-analysis.
Patch testing, used in the assessment of allergic contact dermatitis, is ideally avoided in patients receiving immunosuppressive therapy because of concerns with reductions in accuracy; however, this is not well characterized in the literature. This systematic review summarizes patch testing results in patients receiving immunosuppressive therapy. We identified 16 studies, comprising 195 patients with dermatitis or psoriasis, who were patch tested while receiving immunosuppressants. Of these, 7 studies, comprising 85 patients with dermatitis, patch tests were performed before and during immunosuppression. Overall, 67.9% (n = 19) of the dermatitis patients receiving dupilumab maintained positive reactions to an allergen that previously graded as a 2+/3+ reaction. Several immunosuppressants were also associated with positive patch test results for various allergens. These include dupilumab, cyclosporine, and low-dose prednisone (≤10 mg/d) for dermatitis, and tumor necrosis factor α inhibitors, ustekinumab, an reactions to an allergen that previously graded as a 2+/3+ reaction. Several immunosuppressants were also associated with positive patch test results for various allergens. These include dupilumab, cyclosporine, and low-dose prednisone (≤10 mg/d) for dermatitis, and tumor necrosis factor α inhibitors, ustekinumab, and methotrexate for psoriasis. Ideally, it is preferable to patch test when patients are not receiving oral immunosuppressants or immunomodulators. However, clinicians may choose to assess the risks and benefits of patch testing for each patient given the impact of allergic contact dermatitis on patient quality of life.
The aim of this scoping review was to map teaching strategies incorporating Quality and Safety Education for Nurses (QSEN) competencies and assessment tools based on the QSEN framework.

The search was conducted through MEDLINE, Embase, Scopus, and Web of Science databases and carried out through the framework developed by Arksey and O'Malley and revised by Levac et al.

Thirty-one studies were included. Among QSEN competences, patient-centered care, safety, and teamwork and collaboration were most frequently incorporated into teaching strategies. Most assessment tools aimed at capturing the achievement of QSEN competencies after a classroom learning experience.

The scoping review made it possible to identify various teaching strategies and assessment tools developed on the QSEN framework. Further studies are needed to test teaching strategies to facilitate students' acquisition of QSEN competencies in clinical environments.
The scoping review made it possible to identify various teaching strategies and assessment tools developed on the QSEN framework. Further studies are needed to test teaching strategies to facilitate students' acquisition of QSEN competencies in clinical environments.
Mastering the Content is a proactive curriculum whose At-Risk Student Identification Criteria-Based Remediation Interventions Tool leads to nursing student success. The curriculum integrates active learning strategies and problem-solving activities throughout the nursing program to develop clinical judgment. Remediation includes guided metacognitive learning tool construction, individualized student support, and study plans to increase learning and decrease attrition. The curriculum and interventions tool were developed based on evidence gathered from a meta-analysis of research on best practices in basic RN prelicensure program remediation success and one nursing program's successful implementation of best practices.
Mastering the Content is a proactive curriculum whose At-Risk Student Identification Criteria-Based Remediation Interventions Tool leads to nursing student success. The curriculum integrates active learning strategies and problem-solving activities throughout the nursing program to develop clinical judgment. Remediation includes guided metacognitive learning tool construction, individualized student support, and study plans to increase learning and decrease attrition. The curriculum and interventions tool were developed based on evidence gathered from a meta-analysis of research on best practices in basic RN prelicensure program remediation success and one nursing program's successful implementation of best practices.
The daily evolution of the nursing profession has charged nurse educators to be innovative and creative in their teaching strategies, with the goal of engaging and motivating students and promoting lifelong learning. Educational escape rooms use multiple teaching/learning strategies, such as problem-based learning, flipping the classroom, and gamification, to engage learners and promote active learning. The educational escape room experience provides a way to engage and empower nursing students and assist in meeting learning objectives. This article describes an interactive educational escape activity for hematologic disorders.
The daily evolution of the nursing profession has charged nurse educators to be innovative and creative in their teaching strategies, with the goal of engaging and motivating students and promoting lifelong learning. Educational escape rooms use multiple teaching/learning strategies, such as problem-based learning, flipping the classroom, and gamification, to engage learners and promote active learning. The educational escape room experience provides a way to engage and empower nursing students and assist in meeting learning objectives. This article describes an interactive educational escape activity for hematologic disorders.
With the implementation of five remediation strategies immediately after the first failed exam in a pharmacology course, this quality improvement study demonstrated an increase in retention of at-risk associate degree nursing students. Unit exam scores and course failure rates were measured before and after implementation. Twelve of 14 students who completed the remediation demonstrated a statistically significant increase in scores from the first failed exam to the last exam taken. The mean increase was 17.3 percentage points (p < .0001, 95 percent confidence interval [13.3, 20.9]). Cohen's d, which equaled 0.604, indicated a significant increase in course pass rates.
With the implementation of five remediation strategies immediately after the first failed exam in a pharmacology course, this quality improvement study demonstrated an increase in retention of at-risk associate degree nursing students. Unit exam scores and course failure rates were measured before and after implementation. Twelve of 14 students who completed the remediation demonstrated a statistically significant increase in scores from the first failed exam to the last exam taken. The mean increase was 17.3 percentage points (p less then .0001, 95 percent confidence interval [13.3, 20.9]). Cohen's d, which equaled 0.604, indicated a significant increase in course pass rates.
A purpose of this activity was to determine if an escape room activity could familiarize prospective students with information about a program, nurture an interest in a nursing career, and expose individuals to active teaching strategies. Ten prospective nursing students participated in an escape room recruitment activity that introduced them to aspects of nursing care. The activity decreased participants' nervousness about beginning the nursing program. Escape rooms are an active and engaging strategy that can be used to introduce prospective students to nursing and facilitate team building for groups.
A purpose of this activity was to determine if an escape room activity could familiarize prospective students with information about a program, nurture an interest in a nursing career, and expose individuals to active teaching strategies. Ten prospective nursing students participated in an escape room recruitment activity that introduced them to aspects of nursing care. The activity decreased participants' nervousness about beginning the nursing program. Escape rooms are an active and engaging strategy that can be used to introduce prospective students to nursing and facilitate team building for groups.
Female reproductive aging remains one of the key unsolved challenges in the field of reproductive medicine. This article reviews three of the most recent and cutting-edge strategies that are currently being investigated to address the issues of poor ovarian response (POR) and primary ovarian insufficiency (POI).

Publications revealing the mechanism of mechanical disruption of the Hippo signaling pathway paved the way to studies on its potential application for fertility treatments. This, in combination with Akt stimulation, resulted in live births and ongoing pregnancies in women with POI. Building on previous reports on the effects of bone marrow transplants on fertility after chemotherapy, another approach involved autologous stem cell ovarian transplantation (ASCOT). The method proved effective in achieving live births in women previously diagnosed with POR. 3,4-Dichlorophenyl isothiocyanate supplier A third approach, intraovarian injection of autologous platelet-rich plasma, resulted in live births and ongoing pregnancies both spontaneously and via in vitro fertilization (IVF) in women with POI and POR.

New paths are being charted to address the issues of POI and POR. Although these are preliminary studies that should be interpreted with caution, they represent great promise for the women affected by these conditions and the physicians treating them.
New paths are being charted to address the issues of POI and POR. Although these are preliminary studies that should be interpreted with caution, they represent great promise for the women affected by these conditions and the physicians treating them.
Endometrial stem cells (ESCs) are multipotent cells that are thought to originate locally in the endometrium as well as in the bone marrow (BM). They have remarkable plasticity and hold promise as an autologous source for regenerative medicine. This review focuses on recent studies that have advanced our understanding of the biology and function of ESCs and BM-derived stem cells (BMDSCs) as related to physiological reproductive processes and pathologies. Moreover, it reviews recent data on potential therapeutic applications of stem cells to endometrial disorders that lead to reproductive failure.

Growing evidence from basic and preclinical studies suggests that ESCs participate in endometrial tissue regeneration and repair. Recent evidence also suggests that ESCs and BMDSCs play important roles in physiological reproductive functions including decidualization, implantation, pregnancy maintenance, and postpartum uterine remodeling. Initial preclinical and clinical studies with ESCs and BMDSCs suggest they have the potential to provide new therapies for various endometrial disorders associated with reproductive failure.

Uterine ESCs and BMDSCs appear to play an important biological role in reproductive success and failure, and have the potential to become treatment targets for reproductive diseases including recurrent implantation failure, thin endometrium, Asherman, and recurrent pregnancy loss.
Uterine ESCs and BMDSCs appear to play an important biological role in reproductive success and failure, and have the potential to become treatment targets for reproductive diseases including recurrent implantation failure, thin endometrium, Asherman, and recurrent pregnancy loss.
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