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Objective.Accurate decoding of individual finger movements is crucial for advanced prosthetic control. In this work, we introduce the use of Riemannian-space features and temporal dynamics of electrocorticography (ECoG) signal combined with modern machine learning (ML) tools to improve the motor decoding accuracy at the level of individual fingers.Approach.We selected a set of informative biomarkers that correlated with finger movements and evaluated the performance of state-of-the-art ML algorithms on the brain-computer interface (BCI) competition IV dataset (ECoG, three subjects) and a second ECoG dataset with a similar recording paradigm (Stanford, nine subjects). We further explored the temporal concatenation of features to effectively capture the history of ECoG signal, which led to a significant improvement over single-epoch decoding in both classification (p less then 0.01) and regression tasks (p less then 0.01).Main results.Using feature concatenation and gradient boosted trees (the top-performing model), we achieved a classification accuracy of 77.0% in detecting individual finger movements (six-class task, including rest state), improving over the state-of-the-art conditional random fields by 11.7% on the three BCI competition subjects. In continuous decoding of movement trajectory, our approach resulted in an average Pearson's correlation coefficient (r) of 0.537 across subjects and fingers, outperforming both the BCI competition winner and the state-of-the-art approach reported on the same dataset (CNN + LSTM). Furthermore, our proposed method features a low time complexity, with only less then 17.2 s required for training and less then 50 ms for inference. This enables about 250× speed-up in training compared to previously reported deep learning method with state-of-the-art performance.Significance.The proposed techniques enable fast, reliable, and high-performance prosthetic control through minimally-invasive cortical signals.Three-dimensional (3D) graphene with a high specific surface area and excellent electrical conductivity holds extraordinary potential for molecular gas sensing. Gas molecules adsorbed onto graphene serve as electron donors, leading to an increase in conductivity. However, several challenges remain for 3D graphene-based gas sensors, such as slow response and long recovery time. Therefore, research interest remains in the promotion of the sensitivity of molecular gas detection. In this study, we fabricate oxygen plasma-treated 3D graphene for the high-performance gas sensing of formaldehyde. We synthesize large-area, high-quality, 3D graphene over Ni foam by chemical vapor deposition and obtain freestanding 3D graphene foam after Ni etching. We compare three types of strategies-non-treatment, oxygen plasma, and etching in HNO3solution-for the posttreatment of 3D graphene. Eventually, the strategy for oxygen plasma-treated 3D graphene exceeds expectations, which may highlight the general gas sensing based on chemiresistors.
Approximately 10% of patients with mild traumatic brain injury (mTBI) have intracranial bleeding (complicated mTBI) and 3.5% eventually require neurosurgical intervention, which is mostly available at centers with a higher level of trauma care designation and often requires interhospital transfer. In 2018, the Brain Injury Guidelines (BIG) were updated in the United States to guide emergency department care and patient disposition for complicated mild to moderate TBI. The aim of this study was to validate the sensitivity and specificity of the updated BIG (uBIG) for predicting the need for interhospital transfer in Canadian patients with complicated mTBI.
This study took place at three level I trauma centers. Consecutive medical records of patients with complicated mTBI (Glasgow Coma Scale score 13-15) who were aged ≥ 16 years and presented between September 2016 and December 2017 were retrospectively reviewed. Patients with a penetrating trauma and those who had a documented cerebral tumor or aneurysm we managed at their initial center without the need for transfer to a center with a higher level of neurotrauma care. Although the uBIG could decrease the number of transfers, further refinement of the criteria could improve its specificity.
Mental training is a promising method to improve motor skills. However, transfer of these improvements to different skills or functional activities is still unclear. The purpose of this study was to investigate the effects of mental balance training programs on motor coordination and skill transfer.
Randomized controlled trial.
Fifty-seven healthy adults (28 females and 29 males) aged between 18 and 25years participated in this study. Participants were randomly assigned to 3 groups virtual reality (VR) mental training group, conventional mental training group, and control group. The training program included action observation and motor imagery practice with balance exercise videos. Bulevirtide The VR mental training group trained with a VR head-mounted display and the conventional mental training group trained with a nonimmersive computer monitor for 30 minutes, 3 days per week, for 4 weeks. Coordination skills were tested with 2 separate custom-made obstacle course tests (OCT-1 and OCT-2). OCT tests included croun and skill transfer test results. In addition, VR mental training may have some advantages over conventional mental training. These findings are promising for the use of mental training for prevention and rehabilitation in special populations.
Our findings suggest that both training interventions can significantly improve coordination and skill transfer test results. In addition, VR mental training may have some advantages over conventional mental training. These findings are promising for the use of mental training for prevention and rehabilitation in special populations.Japan has become a super-aged society. To overcome the negative implications of this, practitioners are increasingly using exercise-based interventions to reduce the requirement for long-term care among Japanese older adults. However, no comprehensive means of assessing the wide range of exercise behavioral determinants exists for this population. Thus, the principle aim of this study was to develop a questionnaire based upon the theoretical domains framework-a framework that has synthesized a wide range of behavior change theories. Completed responses were received from 1,000 Japanese older adults who resided in the Kansai area of Japan. Findings were suggestive of good reliability and validity for seven unique psychological determinants of exercise. This study was the first to provide a measurement tool related to a distinct range of psychological determinants of exercise among Japanese older adults.Increasing evidence has suggested that physical activity may modulate gut microbiome composition. We investigated associations of long-term regular exercise with gut microbiota among middle-aged and older urban Chinese individuals. Gut microbiota was assessed using 16S ribosomal ribonucleic acid gene sequencing of stool samples from 2,151 participants from the Shanghai Women's Health Study and Shanghai Men's Health Study. Participants were free of cancer, diabetes, and cardiovascular diseases at the time of stool sample collection. Physical activity was assessed in repeat surveys between 1996 and 2015 using validated questionnaires. Regular exercise was defined as any type of leisure-time physical activity with a standard metabolic equivalent score >3.0. Stool samples were collected using the 95% ethanol method between 2015 and 2018 with an average of 3.0 years (SD = 0.9) after the latest exposure assessment. General linear regression and permutational multivariate analysis of variance were carried out to evaluate associations of microbial α- and β-diversity with regular exercise participation. Logistic regression and linear regression models were used to evaluate the prevalence and relative abundance of individual taxa in association with regular exercise. Regular exercise was significantly associated with β-diversity (Bray-Curtis and Jaccard dissimilarities, both false discovery rates = 0.03%, 0.12% and 0.09% variance explained, respectively) but not with α-diversity. Relative abundance of genus Ruminococcus was significantly lower among regular exercisers compared with nonexercisers (median relative abundance 0.64% vs. 0.81%, false discovery rate less then 0.10). Further studies are needed to validate the findings from this study and evaluate health benefits of regular exercise on gut microbiota.
Range of motion (ROM) and muscular strength are the main factors that affect athletic performance. Self-myofascial release is a flexibility technique, which is used to inhibit overactive muscle fibers.
To investigate the effects of the 8-week self-myofascial release on the isokinetic hamstrings-to-quadriceps strength ratio (H/QRatio) and the ROM of the knee joint among male athletes with the hamstring shortness.
A randomized controlled trial.
Research laboratory.
Twenty-four college-aged male athletes with hamstring shortness were selected for this study and were randomly assigned to a foam rolling group (FOAM, n = 12) and a control group (n = 12).
Participants in the FOAM group performed supervised self-myofascial release program 3 times per week for 8weeks. The control group received no intervention.
Data were analyzed via 2-way repeated-measure analysis of variance at the significance level of .05.
ROM and the H/QRatio at the velocities of 60°/s, 120°/s, and 180°/s were measured by an isokinetic dynamometer.
The results of 2-way repeated-measure analysis of variance demonstrated that hamstring ROM increased in FOAM group (P = .001). No significant changes were found in H/QRatio after self-myofascial release for FOAM group (P ≥ .05).
When compared with other methods of stretching, self-myofascial release with foam rolling may be beneficial in increasing ROM without decreasing H/QRatio in people with the hamstring shortness.
When compared with other methods of stretching, self-myofascial release with foam rolling may be beneficial in increasing ROM without decreasing H/QRatio in people with the hamstring shortness.
Quadriceps activation failure has been observed following various pathological conditions in a knee joint such as knee surgery, pain, effusion in knee, and osteoarthritis also could be aging matter. Those patients are unable to attain maximal quadriceps strength for a long period of time although their quadriceps itself is not damaged. This impairment is termed arthrogenic muscle inhibition (AMI). AMI has been of concern to clinicians because this weakness hinders the rehabilitation process considerably and delays recovery because strengthening protocols for the AMI could be largely ineffective. Clinically, it is important to understand neurophysiological mechanisms of the AMI to treat patients with the impairment.
This is a narrative review of the literature. The purpose of this review is to understand the following (1) Why investigations of only peripheral spinal reflexive pathways are not enough for elucidation of the mechanisms of the AMI? (2) What we know about the role of the gamma spindle system in AMI so far? (3) Could a dysfunctional gamma spindle system contribute to AMI lead neural changes in upper central nervous system? and (4) Concerns that a clinician should take into consideration when deciding whether to apply therapeutic interventions for AMI.
Here's my website: https://www.selleckchem.com/peptide/bulevirtide-myrcludex-b.html
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