Notes

Dirac semimetal phase as well as changing of wedding ring inversion in XMg2Bi2 (X = Ba and Sr).
Due to the agricultural labor supply in the province of Huelva, the immigrant population has been growing, establishing a situation of irregularity that favors precarious work and hinders access to decent housing. Therefore, our objective was to identify the socio-sanitary needs of the immigrant population facing the living conditions with which they live in the irregular settlements of the province of Huelva.

Cross-sectional descriptive study of mixed method on an estimated population of 2500 residents in 23 settlements. A quantitative study of socio-sanitary variables was carried out using a survey and observation guide, and a water, air and soil quality study. Semi-structured interviews were conducted with 13 inhabitants of the settlements until the saturation of the speeches.

The settlements were located far away from the towns. Surrounded by garbage, without running water, electricity, sewer, toilets or showers. Its residents were stocked up on purchased food and water from fields, wells and publicis key for them, preventing them regularized employment contracts and the perception of being able to access to a better future. Their self-perception of health is good and they do not make a greater use of health services, despite the conditions in which they live.
The success of policies to eradicate COVID-19 depends on the acceptance of vaccines among the population. This paper measures the influence on the intention to get vaccinated of three usual variables in studies on consumer behavior the perception of the efficiency and risk of the vaccine and the social influence.

It was used a survey of 600 residents in Spain that was answered during September 2020 has been used. That survey was conveniently stratified by age and monthly income. The impact of the explanatory variables on the intention to use the vaccine was measured with generalized linear models logistic regression and truncated negative binomial regression. Contro variables were gender, age and monthly income.

We have observed a positive (negative) influence of the variables efficacy perception and social influence (perception of risk), i.e. a ratio of rate use above (below) 1 that is statistically significant (p<0.01 in the case of the first two variables and p<0.05 in the third). Their importance follows the order described above. Neither gender nor age were significant in the intention to get vaccinated, but the income level was. We identified that at the highest income levels there was a greater propensity to reject the vaccine (p<0.1).

The results may be useful to guide the information policy that health authorities should carry out in order to induce the population to use the SARS-CoV-2 vaccine.
The results may be useful to guide the information policy that health authorities should carry out in order to induce the population to use the SARS-CoV-2 vaccine.
The viewing of mainstream pornography can in some situations be detrimental to the sexual and reproductive health of adolescents. This consumption generates gender inequalities by distorting the image of women. The aim of this study was to review the existing literature on the effects of mainstream pornography use on sexual and reproductive health in adolescents and university students.

A scoping review was conducted to examine the existing literature on the sexual and reproductive health effects of mainstream pornography use in adolescents and college students. The purpose of this review is to explore the evidence on this topic by assessing a wide range of articles and study designs. The proposed scoping review has been conducted in accordance with the Joanna Briggs Institute methodology (JBI).

We identified 14 studies showing that mainstream pornography consumption may have a short- and long-term impact on adolescent sexual health. Adolescent exposure to a sexualized media environment is associated with stronger beliefs that females are sexual objects.

Pornography viewing influences adolescent sexual and reproductive health. The sexual misrepresentation of women caused by viewing mainstream pornographic material is a serious problem that can increase gender inequality. Mainstream pornography should be addressed in sexual education programs in schools, as well as in the different Public Health institutions.
Pornography viewing influences adolescent sexual and reproductive health. The sexual misrepresentation of women caused by viewing mainstream pornographic material is a serious problem that can increase gender inequality. Mainstream pornography should be addressed in sexual education programs in schools, as well as in the different Public Health institutions.
The population-based Program for the Prevention of Colorectal Cancer (PPCRC) was implemented in 2005 in the Valencian Community, following the guidelines of the European Union. To achieve the desired effectiveness in these programs, it is necessary to achieve a series of requirements, assessable through the program indicators. The objective of this study was to analyze the evolution of the program indicators from 2006 to 2016.

The accumulated indicators for the period were calculated. The Poisson regression model was used to compare the indicators by age groups and sex, by type of screening, by type of fecal occult blood test (FOBT) and by year.

The number of people invited to participate was 1,934,266. The participation rate was 44.4%, being 87.6% in the subsequent screening and 33.7% in the initial one, with men over 60 having the lowest participation figures. Except for the positive predictive value (PPV) for low risk adenomas, which was higher in a group of men aged 50 to 59 years of successive screening, the detection rates and PPV for the different types of lesions were higher in the initial screening, with immunological test and in the group of men over 60 years old. Throughout the period, there was a decrease in the test positivity rates and in the advanced adenomas and cancers detection rates.

The PPCCR reaches levels of quality for which the effectiveness of the program is demonstrated. However, the insufficient participation of some population groups highlights the need to carry out studies to achieve the desired objectives in all population groups and thus result in greater effectiveness of the program.
The PPCCR reaches levels of quality for which the effectiveness of the program is demonstrated. However, the insufficient participation of some population groups highlights the need to carry out studies to achieve the desired objectives in all population groups and thus result in greater effectiveness of the program.BACKGROUND This study was designed to illustrate the effects and latent mechanism of lncRNA maternally expressed gene 3 (MEG3) on intracerebral hemorrhage (ICH)-induced brain injury. MATERIAL AND METHODS An ICH rat model was generated to determine the role of lncRNA MEG3 in ICH. The interaction between lncRNA MEG3 and microRNA (miR)-181b were confirmed by Starbase and dual-luciferase reporter assay. One hour (h) or 3 days after ICH stimulation, rat neurological injury was evaluated by modified Neurological Severity Score (mNSS). Brain water content and cell apoptosis were assessed using brain edema assessment and flow cytometry (FCM), respectively. Caspase3 activity was also determined. Enzyme-linked immunosorbent assay (ELISA) was applied to evaluate the levels of pro-inflammatory cytokines. Moreover, the representative biomarkers of oxidative stress were evidenced using detection kits. RESULTS The lncRNA MEG3 level in ICH rat brain tissues was higher than that in the sham group. miR-181b was a direct target of lncRNA MEG3 and it was downregulated in brain tissues of ICH rats. Notably, we found that neurobehavioral scores, brain water content, and neuronal apoptosis were decreased and caspase3 activity was reduced in MEG3-shRNA-treated ICH rats, while we observed the opposite result in ICH+MEG3-shRNA+miR-181b inhibitor rats. Further analyses revealed that MEG3-shRNA inhibited inflammatory cytokines release and reduced oxidative stress. All these results were reversed by miR-181b inhibitor. In addition, MEG3-shRNA activated the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway, which was reversed by miR-181b inhibitor. CONCLUSIONS MEG3-shRNA restrained oxidative stress and inflammation following ICH in an miR-181b-dependent manner.BACKGROUND Antituberculosis drug-induced hepatotoxicity (ADIH) is a possible adverse event of antitubercular treatment. There are still no official guidelines for ADIH management in children. Recurrent ADIH is infrequently reported. Lirametostat manufacturer CASE REPORT In this article, we report 6 unusual cases of recurrent ADIH in children. Five children developed ADIH during the intensive phase. Streptomycin and ethambutol were given to those with tuberculosis meningitis, urinary tract tuberculosis, and one patient with pulmonary tuberculosis with HIV infection and cardiac comorbidities. Five patients experienced a second ADIH episode after reintroduction. One patient developed ADIH symptoms again before reaching a full dose of isoniazid. The patient with pulmonary tuberculosis, HIV infection, and dilated cardiomyopathy experienced secondary episodes of ADIH and received levofloxacin and ethambutol as additional drugs. CONCLUSIONS Recurrent ADIH is relatively uncommon in children but may be encountered in daily practice. Reintroduction of previous treatment regimens should be tailored individually. There is an urgent need for standardized guidelines for ADIH in children.BACKGROUND Our kidney transplant waitlist includes 20% re-transplantations (TX2). Knowing what to expect is a clinical obligation. MATERIAL AND METHODS We compared graft and patient survival of all 162 TX2 patients, transplanted 2000 to 2009, with 162 patients after first transplantation (TX1) matched for age, sex, living/non-living donation, and transplantation date. Patient follow-up was 10 years. RESULTS TX2 graft and patient survivals were inferior to TX1 (p less then 0.001 and p=0.047). TX2 patients had a longer cumulative dialysis vintage, more human leucocyte antigen (HLA) mismatches, more panel-reactive HLA antibodies, more often received induction therapy with rabbit-antithymocyte globulin (rATG), and had a lower body mass index (all p less then 0.05). Death from infection and graft failure by rejection was more frequent after TX2 (both p less then 0.05) but not after TX1. Multivariable Cox regression analysis revealed that both cohorts had graft failure and death risk associated with infection and cardiovascular disease, and graft failure by humoral rejection. However, only TX2 patients had an additional risk of graft failure with early inferior graft function and of patient death with ≥2 comorbidities. Moreover, Kaplan-Meier analysis showed that TX2 and not TX1 patients had a lower graft and patient survival associated with infection and with ≥2 comorbidities (all p less then 0.05). CONCLUSIONS Re-transplantation is associated with worse graft outcomes mainly because of immunologic and graft-quality reasons, although the high number of comorbidities and infection severities aside from cardiovascular disease drive mortality. The more frequent rATG induction of TX2 patients could promote infection by enhancing immunosuppression. By addressing comorbidities, outcomes could possibly be improved.
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